TMPRSS3 (NM_024022) Human Untagged Clone

CAT#: SC111838

TMPRSS3 (untagged)-Human transmembrane protease, serine 3 (TMPRSS3), transcript variant A

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TMPRSS3
• Synonyms: DFNB8; DFNB10; ECHOS1; TADG12
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_024022, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGGAAAATGATCCGCCTGCTGTTGAAGCCCCCTTCTCATTCCGATCGCTTTTTGGCCTTGATGATT
  TGAAAATAAGTCCTGTTGCACCAGATGCAGATGCTGTTGCTGCACAGATCCTGTCACTGCTGCCATTGAA
  GTTTTTTCCAATCATCGTCATTGGGATCATTGCATTGATATTAGCACTGGCCATTGGTCTGGGCATCCAC
  TTCGACTGCTCAGGGAAGTACAGATGTCGCTCATCCTTTAAGTGTATCGAGCTGATAGCTCGATGTGACG
  GAGTCTCGGATTGCAAAGACGGGGAGGACGAGTACCGCTGTGTCCGGGTGGGTGGTCAGAATGCCGTGCT
  CCAGGTGTTCACAGCTGCTTCGTGGAAGACCATGTGCTCCGATGACTGGAAGGGTCACTACGCAAATGTT
  GCCTGTGCCCAACTGGGTTTCCCAAGCTATGTGAGTTCAGATAACCTCAGAGTGAGCTCGCTGGAGGGGC
  AGTTCCGGGAGGAGTTTGTGTCCATCGATCACCTCTTGCCAGATGACAAGGTGACTGCATTACACCACTC
  AGTATATGTGAGGGAGGGATGTGCCTCTGGCCACGTGGTTACCTTGCAGTGCACAGCCTGTGGTCATAGA
  AGGGGCTACAGCTCACGCATCGTGGGTGGAAACATGTCCTTGCTCTCGCAGTGGCCCTGGCAGGCCAGCC
  TTCAGTTCCAGGGCTACCACCTGTGCGGGGGCTCTGTCATCACGCCCCTGTGGATCATCACTGCTGCACA
  CTGTGTTTATGACTTGTACCTCCCCAAGTCATGGACCATCCAGGTGGGTCTAGTTTCCCTGTTGGACAAT
  CCAGCCCCATCCCACTTGGTGGAGAAGATTGTCTACCACAGCAAGTACAAGCCAAAGAGGCTGGGCAATG
  ACATCGCCCTTATGAAGCTGGCCGGGCCACTCACGTTCAATGAAATGATCCAGCCTGTGTGCCTGCCCAA
  CTCTGAAGAGAACTTCCCCGATGGAAAAGTGTGCTGGACGTCAGGATGGGGGGCCACAGAGGATGGAGCA
  GGTGACGCCTCCCCTGTCCTGAACCACGCGGCCGTCCCTTTGATTTCCAACAAGATCTGCAACCACAGGG
  ACGTGTACGGTGGCATCATCTCCCCCTCCATGCTCTGCGCGGGCTACCTGACGGGTGGCGTGGACAGCTG
  CCAGGGGGACAGCGGGGGGCCCCTGGTGTGTCAAGAGAGGAGGCTGTGGAAGTTAGTGGGAGCGACCAGC
  TTTGGCATCGGCTGCGCAGAGGTGAACAAGCCTGGGGTGTACACCCGTGTCACCTCCTTCCTGGACTGGA
  TCCACGAGCAGATGGAGAGAGACCTAAAAACCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024022 unedited
  ACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGGTTTATGGGAAGCCAGTAACACT
  GTGGCCTACTATCTCTTCCGTGGTGCCATCTACATTTTTGGGACTCGGGAATTATGAGGT
  AGAGGTGGAGGCGGAGCCGGATGTCAGAGGTCCTGAAATAGTCACCATGGGGGAAAATGA
  TCCGCCTGCTGTTGAAGCCCCCTTCTCATTCCGATCGCTTTTTGGCCTTGATGATTTGAA
  AATAAGTCCTGTTGCACCAGATGCAGATGCTGTTGCTGCACAGATCCTGTCACTGCTGCC
  ATTGAAGTTTTTTCCAATCATCGTCATTGGGATCATTGCATTGATATTAGCACTGGCCAT
  TGGTCTGGGCATCCACTTCGACTGCTCAGGGAAGTACAGATGTCGCTCATCCTTTAAGTG
  TATCGAGCTGATAGCTCGATGTGACGGAGTCTCGGATTGCAAAGACGGNGAGGACGAGTA
  CCGCTGTGTCCGGGTGGGTGGTCAGAATGCCGTGCTCCAGGTGTTCACAGCTGCTTCGTG
  GAAGACCATGTGCTCCGATGACTGGAAGGGTCACTACGCAAATGTTGCCTGTGCCCAACT
  GGGTTTCCCAAAGCTATGTAGNTCAGATAACCTCAGAGTGAGCTCGCTGGAGGGGCAGTT
  CCGGGGAGAGTTTGTGTCCATCGATCACCTCTTGCCAGATGACANGGTGACTGCATTACA
  CCACTCAGTATATGTGAGGGAGGGATGTGCCCTCTGCCACGTGGTTACCTTGCAGTGCAC
  AGCCTGTGGTCATAGAAGGGGCTACAGCTCACGCATCGTGGGNTGAAACATGTNCTTGCT
  CTCGCAGTGGCCCTGGCANGCCANNCTTCAGTCCAGGGCTACCCACTGTGCGGNGGCTCT
  GCATCACGCCCCTGTGATATACTGCTGCCACTGNGTTATGACTNGACCTCCCAAGTCATG
  ACANCAGGTGGTCTAGNTTCCTGTTGACAATCANNCATCCACTGNTGGAAAAATGTTACC
  CGCAGACAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_024022 unedited
  ACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGAGGGAAGGAAACATA
  TTATTTGGAATCAAAGGACAATAATACGTCAAGCACCAAATGCTACAAAGAAATCATGAA
  AATAGGCCTTAAACGAGTCATTCCTAGATTAACCTCCCCACATGTGAAAATAAGTCTTGG
  AAGTAGAAAGGGTGGGTTTGGTTCTGGTCCCTAGAGATGAAAACGTGCAGTGACTGCAGT
  TCTGCACTTCTGGGCTGGTGCGTCTTTTCTGAGTGGCTGTTGGTGGCTTTGCACGTGAGG
  TCACATAACTGCTTATCTCGTCAGGAATTTTGCAAGACCCCTGGAGAGAAAACCAGATGG
  ACCAGTGGGAAAGGCCGCCCTTGCAAGTTGCTGCTTCTTTTGTTCTTAGTGAAGATCAAA
  AAGGAGCGTGAGGCTAGGCGTGGTGGCCCATGCCTGTAATCCCAGCACTGTGGGAGGCTG
  AAGCAGGCACATCATTTGAGGTCAGGGGTTTGAGAGCAGCCTGGCCAACATGGTGAAACC
  CTGTCTCTACTAAAAATACAAAAATTATTTGGGTGTGGTGGCGGGCACCTGTGGTCCCAG
  CTACTGGGGAAGCTGAAGCAAGAGAATCCCTTGCACCATGGAAGCGGAGGCTCGCATGAG
  CAGGGATTTCTCACTGACTTCAGCCTGGCCACAGAACCAGACTCCCTTTAAAAAAACACA
  AACCAAAACCACTTTGAAGGTTGCGCCGGATCACATGGAAGGTGCCTCTTTTCGGCCTTG
  TTCTTGGGCCCGGACTTAAACCTCCAAGGTGCCTGCTCTGCCGCGGTTCTTCCCCGGCAT
  CCCAGGGGGAATCGGCTCTTTTCTTACCTAGGAACCCAGGGGCTTCTTGCCCCTCCCTTC
  CAGGTCCCGGGTTTCTTCCTCTGCTTTGCCCTCTCCCGAACGAGTCACCGCCGCTCCCTT
  CCTTTCCCTTCGCTTCCCGCCATTTCCCCCCCCCTCTTCCCTTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_024022
• ORF Size: 1365 bp
• Insert Size: 2550
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_024022.1, NP_076927.1
• RefSeq Size: 2468
• RefSeq ORF: 1365
• Locus ID: 64699
• Domains: SR, Tryp_SPc, ldl_recept_a
• Protein Families: Druggable Genome, Protease, Transmembrane
• Gene Summary: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
  Transcript Variant: This variant (A) encodes the longest isoform (1).