RIC3 (NM_024557) Human Untagged Clone

CAT#: SC112180

RIC3 (untagged)-Human resistance to inhibitors of cholinesterase 3 homolog (C. elegans) (RIC3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RIC3
• Synonyms: AYST720; PRO1385
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112180 sequence for NM_024557 edited (data generated by NextGen Sequencing)
  ATGGCGTACTCCACAGTGCAGAGAGTCGCTCTGGCTTCTGGGCTTGTCCTGGCTCTGTCG
  CTGCTGCTGCCCAAGGCCTTCCTGTCCCGCGGGAAGCGGCAGGAGCCGCCGCCGACACCT
  GAAGGAAAATTGGGCCGATTTCCACCTATGATGCATCATCACCAGGCACCCTCAGATGGC
  CAGACTCCTGGGGCTCGTTTCCAGAGGTCTCACCTTGCCGAGGCATTTGCAAAGGCCAAA
  GGATCAGGTGGAGGTGCTGGAGGAGGAGGTAGTGGAAGAGGTCTGATGGGGCAGATTATT
  CCAATCTACGGTTTTGGGATTTTTTTATATATACTGTACATTCTATTTAAGCTCTCAAAG
  GGGAAAACAACTGCAGAGGATGGGAAATACTATACTGCCATGCCTGGAAACACCCACAGG
  AAAATTACCAGTTTTGAGCTTGCTCAACTGCAAGAAAAACTGAAGGAGACAGAAGCAGCC
  ATGGAAAAATTAATCAACAGAGTGGGACCTAATGGTGAGAGAGCACAGACTGTGACTTCT
  GACCAAGAGAAACGGTTGCTACATCAGCTCCGAGAAATCACCAGGGTCATGAAAGAAGGA
  AAATTCATTGACAGATTTTCTCCAGAGAAAGAAGCTGAGGAGGCCCCTTACATGGAGGAC
  TGGGAAGGTTACCCTGAAGAGACTTACCCAATTTATGACCTTTCAGACTGTATCAAGCGT
  AGGCAAGAAACAATCTTGGTGGATTACCCTGACCCAAAAGAACTTTCTGCTGAAGAAATA
  GCTGAAAGAATGGGAATGATAGAAGAGGAAGAATCAGATCATTTGGGTTGGGAAAGTCTG
  CCCACTGACCCCAGAGCCCAGGAAGATAATTCTGTTACCTCGTGTGATCCAAAGCCAGAA
  ACATGTTCCTGCTGTTTTCATGAAGACGAGGATCCTGCTGTCTTGGCAGAGAATGCTGGA
  TTCAGTGCAGATAGCTACCCTGAGCAAGAGGAAACCACCAAAGAAGAGTGGTCCCAAGAC
  TTTAAAGATGAAGGGTTGGGCATCAGCACCAATAAAGCATATACAGGCAGCATGCTGAGG
  AAGCGTAACCCCCAGGGTTTAGAGTGA
  
  Clone variation with respect to NM_024557.3
  389 g=>a;1051 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024557 unedited
  GTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGCTGGCGTC
  TGCACCTGCGACCACCGTGAGCAGTCATGGCGTACTCCACAGTGCAGAGAGTCGCTCTGG
  CTTCTGGGCTTGTCCTGGCTCTGTCGCTGCTGCTGCCCAAGGCCTTCCTGTCCCGCGGGA
  AGCGGCAGGAGCCGCCGCCGACACCTGAAGGAAAATTGGGCCGATTTCCACCTATGATGC
  ATCATCACCAGGCACCCTCAGATGGCCAGACTCCTGGGGCTCGTTTCCAGAGGTCTCACC
  TTGCCGAGGCATTTGCAAAGGCCAAAGGATCAGGTGGAGGTGCTGGAGGAGGAGGTAGTG
  GAAGAGGTCTGATGGGGCAGATTATTCCAATCTACGGTTTTGGGATTTTTTTATATATAC
  TGTACATTCTATTTAAGCTCTCAAAGGGGAAAACAACTGCAGAGGATGGGAAATACTATA
  CTGCCATGCCTGGAAACACCCACAGGAAAATTACCAGTTTTGAGCTTGCTCAACTGCAAG
  AAAAACTGAAGGAGACAGAAGCAGCCATGGAAAAATTAATCAACAGAGTGGGACCTAATG
  GTGAGAGAGCACAGACTGTGACTTCTGACCAAGAGAAACGGTTGCTACATCAGCTCCGAG
  AAATCACCAGGGTCATGAAAGAAGGAAAATTCATTGACAGATTTTCTCCAGAGAAGAAGC
  TGANGAGGCCCCTTACATGGANGACTGNGAAGGTTACCCTGAAGAGACTTACCCATTTAT
  GACCTTTCAGACTGTATCAAGCGTAGGCAAGAAACATCTGGTGGATTACCCTGACCAAAA
  GACTTTCTGCTGAAGAATANCTGAAGAATGGGATGATAGAGAGGAGAATAGATCATTTGG
  TG
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_024557 unedited
  GTTAAAAACCTTTTTTTTTGGCAACAAAAACCTGACCCATGATTTTGTCATCCTGGGTTG
  TATATACACATATAACTGTCATCCCCAAAGGATAAAATAATTCTGGAAAATCCAAAAAGA
  ATTTTCTAAATCCTAAATAACTGAAAGGTACATCCAAATGTCTGATATATAAATACACAA
  ATATATTCCTTATATATAAACCAACCAAGAGCTAGGGCAGGAAGAACCACCATAAGGGCT
  TAGTACTTCTGGCAGGAATTTCCATAAGCCAATTTTCCCCAAAGACCAACAACACTTTAC
  ATAACAGCCTCACCAAAATACTTGAACATCCATGTATTTTCACACCCTACTGCTTTTTTC
  AACAACTCTTTCTGCCAAGAGTGTCCTCTCTTCTTTGCCTACCTGAAGAAGTTCTTTGCA
  TGCCTCAAGGCCCACCTCCCAAGAAACTGTGAAGTTTCTTGGCAATACTTTAGCAAAAAC
  AATTTATCTTTCCTGTAGTTTTGGGCCCATGTCTGAATTACAGCATAGCCCTTATAATAA
  AAACATAATTACCACTTAATGAGTGGTTATCATGTATGAGCTAGAACCAATGCTGTTTTA
  CACACACTGATGATTTCATTTAACCAGGACCTTTAATACCCCTCCCTTTACTACCCTGAA
  GCCAAAGCTCAGACCAGTTAAGGAGCTGACCCAAGATTCCACAGCTAGGAAATGCAGGGA
  CAGATCATGGCTCATGTTTCTCTGCCTGCAAGATTCACCAATCTGAGCCCTCTTACAGGG
  GCATAGTTCATTTTATCTGGCAAGCTCTCTCTCGTCACACTGAGTTTTTTGAGGGTAGAG
  ATTGACCTCTGTTCCTAAACCCGGCACTGAACATTGACTGCTTAATGATGAATGAACTTC
  AGAAACCACCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_024557
• ORF Size: 1107 bp
• Insert Size: 4400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_024557.2, NP_078833.2
• RefSeq Size: 2907
• RefSeq ORF: 1107
• Locus ID: 79608
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a member of the resistance to inhibitors of cholinesterase 3-like family which functions as a chaperone of specific 5-hydroxytryptamine type 3 receptor and nicotinic acetylcholine receptor subtypes. The encoded protein influences the folding and assembly of these receptor subunits in the endoplasmic reticulum and expression on the cell surface. This protein contains an N-terminal transmembrane domain, a proline-rich spacer, and a cytosolic C-terminal coiled-coil domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
  Transcript Variant: This variant (1) encodes isoform c. The isoform designation was changed from 'a' to 'c' to be consistent with isoforms cited in PMID 18691158. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.