SECISBP2 (NM_024077) Human Untagged Clone

CAT#: SC112316

SECISBP2 (untagged)-Human SECIS binding protein 2 (SECISBP2)


  "NM_024077" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SECISBP2
Synonyms SBP2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC112316 sequence for NM_024077 edited (data generated by NextGen Sequencing)
ATGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTC
AAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCA
TGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACA
GAGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTAT
TTATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCCTTGACTCCACA
CAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGA
GGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAA
GCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGAC
AGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCAT
TTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGG
AAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTTACCACA
CTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCC
AAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAA
CCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAATCTGTA
ACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATG
GGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACT
TCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGTATACCA
TCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCT
ACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAG
AATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAAGAGCCT
CCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGAC
AGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAAT
GTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCCCTGGAG
AAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGTTGGA
GCAGTGCCAGTCCTTTCCAAAGAATGTGCATCAGGGGAGAGAGGCCGCCGCATGAGTCAA
ATGAAGACCCCGCACAATCCCTTGGACTCCAGCGCCCCACTGATGAAGAAAGGGAAGCAG
AGGGAGATCCCCAAGGCCAAGAAGCCAACCTCACTGAAGAAGATTATTTTGAAAGAACGG
CAAGAGAGAAAGCAGCGTCTCCAAGAAAATGCTGTGAGTCCAGCTTTTACCAGTGATGAC
ACACAAGATGGAGAGAGTGGTGGTGATGACCAGTTTCCCGAGCAGGCAGAGCTGTCAGGG
CCAGAGGGGATGGACGAACTGATCTCCACTCCTTCGGTTGAGGACAAGTCTGAAGAGCCA
CCAGGCACAGAGCTCCAGAGGGACACAGAGGCCTCCCACCTTGCTCCCAATCACACCACC
TTCCCTAAGATCCACAGCCGCAGATTCAGGGATTACTGCAGCCAGATGCTTAGTAAAGAA
GTGGATGCTTGTGTTACCGACCTACTCAAAGAACTGGTCCGTTTCCAAGACCGTATGTAC
CAGAAAGATCCAGTCAAGGCCAAGACTAAACGTCGACTTGTGTTGGGGTTGAGGGAGGTT
CTCAAACACCTGAAGCTCAAAAAACTGAAATGTGTCATTATTTCTCCCAACTGTGAGAAG
ATACAGTCAAAAGGTGGGCTGGATGACACTTTGCACACAATTATTGATTATGCCTGTGAG
CAGAACATTCCCTTTGTGTTTGCTCTCAACCGCAAAGCTCTGGGGCGCAGTTTGAATAAG
GCAGTTCCTGTCAGTGTGGTGGGGATCTTCAGCTATGATGGGGCCCAGGATCAGTTCCAC
AAGATGGTTGAGCTGACAGTGGCGGCCCGACAGGCGTACAAGACCATGCTGGAGAATGTG
CAGCAGGAGCTGGTGGGAGAGCCCAGGCCTCAGGCACCTCCCAGCCTACCCACACAGGGC
CCCAGCTGCCCTGCAGAAGATGGCCCCCCAGCCCTGAAAGAAAAAGAAGAGCCACACTAC
ATTGAAATCTGGAAAAAACATCTGGAAGCATACAGTGGATGTACCCTGGAGCTAGAAGAA
TCCTTGGAGGCTTCAACCTCTCAAATGATGAATTTGAATTTATGA

Clone variation with respect to NM_024077.3
>OriGene 5' read for NM_024077 unedited
ATAGGCGGGCCGCGAATTCGCACGAGGGTCGCCTGCGGGGGCGGAAACGCTTTGTCTGTC
CGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCA
TGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCA
AACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCAT
GTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAG
AGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATT
TATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCCTTGACTCCACAC
AGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAG
GTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAG
CTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGACA
GTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATT
TGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGA
NATCCAGAATCATTGCANAAAATGTATCTACCTNCAAACCTGAGTTTGAAATTACCACAC
TGGNACTTNTCCTGAACTGCANGGTGCANAGNNACATATGTCAGAGATACAGAAGCAACC
CNAGTGGGGACCCTGTNCACTCTGNCTCTACC
>OriGene 3' read for NM_024077 unedited
TGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTAATAATTACT
CTTTATTTAAAATAAATAAGCCCTCTTACTTACAGGGNAAAATATGAAAGCAAACTCTGT
CCTCCTGGTCTAAGACAGAAACCACATTCAGAATATGTTCATTGAAAAAGGAAAGATTTG
TTGATTATCAAACAAATCTAGGTACTTCAATACACATTGTTTCTTTGAAAAATAAAGACT
GAAAGGAATAATTCATTTCAAAAAGTCACAGGTTAGAAAACCAATTTTCCTTCTGAGGCT
CATTTTAGCAAATCCTCCAAGTGTTCCCAAATCTTTTAAAAAAGCTACATCCCCTGAGAA
AGGGCCCTTTCCCTGTAGCCCTCTTGCTCTGACACCAGCAGCCCTGCACCCTTCTGCCAA
GTGGCTCCCTGCAGGACGGTGCTGTTGCCGGGCAGGAATGGCCCTCCATGGCAACCTCCA
GCAGGCAGGAGCTCACCACCTGCTTTCTGCAAACTCACTCACTTGGCTCAGCTATTCTGC
AATGGAGAGGAAGTTTCCTTAGCAGCCAAAGTATTCTAAGTATCACATTTTCCAGTATTT
TCCAGATCCGTAGTGTGCTCAGAAAGCCAGAGCTGTATCACCAGGCTTTTAGAGAAGATT
AACACCTGCACATCTGAGTGACCTTTAACAGGCTNCGCAGCACTGAACGCCTGCAGACAC
TGCTTTATGTGCCCCTTAATGCTGATCAATTTCCAGATTCAACAGTTACACAATTACATT
GTCATGAAAAACCAGAGAAAAAGCCCCAAGTCTTTTTCAGACCTTCCCTCCTTACCCAAA
TACAGACCCCAGGCAGAACTTTATAAATTCAATTCATCATTGGGAGGTTGAACCTTCAGG
TATTTTTAGCTCCGGGACATCCCTGATGCTTCAAAGATTTTTCAATTAAAGAAGGGGTTT
TCTTTTTTTAGGCGGGGGCTTTTTCAGGACTGGGCCTGGGGAACTTA
Restriction Sites NotI-NotI     
ACCN NM_024077
ORF Size 2565 bp
Insert Size 3630
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_024077.2, NP_076982.2
RefSeq Size 3457
RefSeq ORF 2565
Locus ID 79048
Domains Ribosomal_L7Ae
Gene Summary The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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