SECISBP2 (NM_024077) Human Untagged Clone

CAT#: SC112316

SECISBP2 (untagged)-Human SECIS binding protein 2 (SECISBP2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SECISBP2
• Synonyms: SBP2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112316 sequence for NM_024077 edited (data generated by NextGen Sequencing)
  ATGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTC
  AAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCA
  TGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACA
  GAGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTAT
  TTATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCCTTGACTCCACA
  CAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGA
  GGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAA
  GCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGAC
  AGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCAT
  TTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGG
  AAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTTACCACA
  CTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCC
  AAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAA
  CCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAATCTGTA
  ACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATG
  GGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACT
  TCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGTATACCA
  TCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCT
  ACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAG
  AATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAAGAGCCT
  CCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGAC
  AGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAAT
  GTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCCCTGGAG
  AAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGTTGGA
  GCAGTGCCAGTCCTTTCCAAAGAATGTGCATCAGGGGAGAGAGGCCGCCGCATGAGTCAA
  ATGAAGACCCCGCACAATCCCTTGGACTCCAGCGCCCCACTGATGAAGAAAGGGAAGCAG
  AGGGAGATCCCCAAGGCCAAGAAGCCAACCTCACTGAAGAAGATTATTTTGAAAGAACGG
  CAAGAGAGAAAGCAGCGTCTCCAAGAAAATGCTGTGAGTCCAGCTTTTACCAGTGATGAC
  ACACAAGATGGAGAGAGTGGTGGTGATGACCAGTTTCCCGAGCAGGCAGAGCTGTCAGGG
  CCAGAGGGGATGGACGAACTGATCTCCACTCCTTCGGTTGAGGACAAGTCTGAAGAGCCA
  CCAGGCACAGAGCTCCAGAGGGACACAGAGGCCTCCCACCTTGCTCCCAATCACACCACC
  TTCCCTAAGATCCACAGCCGCAGATTCAGGGATTACTGCAGCCAGATGCTTAGTAAAGAA
  GTGGATGCTTGTGTTACCGACCTACTCAAAGAACTGGTCCGTTTCCAAGACCGTATGTAC
  CAGAAAGATCCAGTCAAGGCCAAGACTAAACGTCGACTTGTGTTGGGGTTGAGGGAGGTT
  CTCAAACACCTGAAGCTCAAAAAACTGAAATGTGTCATTATTTCTCCCAACTGTGAGAAG
  ATACAGTCAAAAGGTGGGCTGGATGACACTTTGCACACAATTATTGATTATGCCTGTGAG
  CAGAACATTCCCTTTGTGTTTGCTCTCAACCGCAAAGCTCTGGGGCGCAGTTTGAATAAG
  GCAGTTCCTGTCAGTGTGGTGGGGATCTTCAGCTATGATGGGGCCCAGGATCAGTTCCAC
  AAGATGGTTGAGCTGACAGTGGCGGCCCGACAGGCGTACAAGACCATGCTGGAGAATGTG
  CAGCAGGAGCTGGTGGGAGAGCCCAGGCCTCAGGCACCTCCCAGCCTACCCACACAGGGC
  CCCAGCTGCCCTGCAGAAGATGGCCCCCCAGCCCTGAAAGAAAAAGAAGAGCCACACTAC
  ATTGAAATCTGGAAAAAACATCTGGAAGCATACAGTGGATGTACCCTGGAGCTAGAAGAA
  TCCTTGGAGGCTTCAACCTCTCAAATGATGAATTTGAATTTATGA
  
  Clone variation with respect to NM_024077.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024077 unedited
  ATAGGCGGGCCGCGAATTCGCACGAGGGTCGCCTGCGGGGGCGGAAACGCTTTGTCTGTC
  CGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCA
  TGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCA
  AACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCAT
  GTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAG
  AGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATT
  TATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCCTTGACTCCACAC
  AGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAG
  GTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAG
  CTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGACA
  GTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATT
  TGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGA
  NATCCAGAATCATTGCANAAAATGTATCTACCTNCAAACCTGAGTTTGAAATTACCACAC
  TGGNACTTNTCCTGAACTGCANGGTGCANAGNNACATATGTCAGAGATACAGAAGCAACC
  CNAGTGGGGACCCTGTNCACTCTGNCTCTACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_024077 unedited
  TGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTAATAATTACT
  CTTTATTTAAAATAAATAAGCCCTCTTACTTACAGGGNAAAATATGAAAGCAAACTCTGT
  CCTCCTGGTCTAAGACAGAAACCACATTCAGAATATGTTCATTGAAAAAGGAAAGATTTG
  TTGATTATCAAACAAATCTAGGTACTTCAATACACATTGTTTCTTTGAAAAATAAAGACT
  GAAAGGAATAATTCATTTCAAAAAGTCACAGGTTAGAAAACCAATTTTCCTTCTGAGGCT
  CATTTTAGCAAATCCTCCAAGTGTTCCCAAATCTTTTAAAAAAGCTACATCCCCTGAGAA
  AGGGCCCTTTCCCTGTAGCCCTCTTGCTCTGACACCAGCAGCCCTGCACCCTTCTGCCAA
  GTGGCTCCCTGCAGGACGGTGCTGTTGCCGGGCAGGAATGGCCCTCCATGGCAACCTCCA
  GCAGGCAGGAGCTCACCACCTGCTTTCTGCAAACTCACTCACTTGGCTCAGCTATTCTGC
  AATGGAGAGGAAGTTTCCTTAGCAGCCAAAGTATTCTAAGTATCACATTTTCCAGTATTT
  TCCAGATCCGTAGTGTGCTCAGAAAGCCAGAGCTGTATCACCAGGCTTTTAGAGAAGATT
  AACACCTGCACATCTGAGTGACCTTTAACAGGCTNCGCAGCACTGAACGCCTGCAGACAC
  TGCTTTATGTGCCCCTTAATGCTGATCAATTTCCAGATTCAACAGTTACACAATTACATT
  GTCATGAAAAACCAGAGAAAAAGCCCCAAGTCTTTTTCAGACCTTCCCTCCTTACCCAAA
  TACAGACCCCAGGCAGAACTTTATAAATTCAATTCATCATTGGGAGGTTGAACCTTCAGG
  TATTTTTAGCTCCGGGACATCCCTGATGCTTCAAAGATTTTTCAATTAAAGAAGGGGTTT
  TCTTTTTTTAGGCGGGGGCTTTTTCAGGACTGGGCCTGGGGAACTTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_024077
• ORF Size: 2565 bp
• Insert Size: 3630
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_024077.2, NP_076982.2
• RefSeq Size: 3457
• RefSeq ORF: 2565
• Locus ID: 79048
• Domains: Ribosomal_L7Ae
• Gene Summary: The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
  Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.