RAB3IP (NM_022456) Human Untagged Clone

CAT#: SC112519

RAB3IP (untagged)-Human RAB3A interacting protein (rabin3) (RAB3IP), transcript variant alpha 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAB3IP
• Synonyms: RABIN3; RABIN8
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112519 sequence for NM_022456 edited (data generated by NextGen Sequencing)
  ATGGCTAATGATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCG
  GACCTTCTTGGTGTGTATGAATCAGGAACTCAAGAGCAGACTACCTCACCAAGTGTCATC
  TACCGGCCACACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCAAATGCATTAGATGTT
  TCTGAACTTCCTACACAACCCGTGTATTCATCCCCCAGACGTTTAAATTGTGCGGAAATA
  TCTAGTATCAGCTTTCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCT
  GGATTAACTAAATTAACTACAAGAAAGGACAACTATAATGCAGAGAGAGAGTTTTTACAG
  GGTGCTACTATAACAGAGGCTTGCGATGGCAGTGATGATATTTTTGGGTTGAGTACTGAT
  AGTCTGTCTCGTTTACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGA
  TTAAAAGAAGAACTCGCAAAAGCTCAGAGGGAACTGAAGTTAAAAGATGAAGAATGTGAG
  AGGCTTTCAAAAGTGCGAGATCAACTTGGACAGGAATTGGAAGAACTCACAGCTAGTCTA
  TTTGAGGAAGCTCATAAAATGGTGAGAGAAGCAAATATCAAGCAGGCAACAGCAGAAAAA
  CAGCTAAAAGAAGCACAAGGAAAAATTGATGTACTTCAAGCTGAAGTAGCTGCATTGAAG
  ACACTTGTATTGTCCAGTTCTCCAACATCACCTACGCAGGAGCCTTTGCCAGGTGGAAAG
  ACACCTTTTAAAAAGGGGCATACAAGAAATAAAAGCACAAGCAGTGCTATGAGTGGCAGT
  CATCAGGACCTCAGTGTGATACAGCCAATTGTAAAAGACTGCAAAGAGGCTGACTTATCC
  TTGTATAATGAATTCCGATTGTGGAAGGATGAGCCCACAATGGACAGGACGTGTCCTTTC
  TTAGACAAAATCTACCAGGAAGATATCTTTCCATGTTTAACATTCTCAAAAAGTGAGTTG
  GCTTCAGCTGTTCTGGAGGCTGTGGAAAACAATACTCTAAGCATTGAACCAGTGGGATTA
  CAACCTATCCGGTTTGTGAAAGCTTCTGCAGTTGAATGCGGAGGACCAAAAAAATGTGCT
  CTCACTGGCCAGAGTAAGTCCTGTAAACACAGAATTAAATTAGGGGACTCAAGCAACTAT
  TATTATATTTCTCCTTTTTGCAGATACAGGATCACTTCTGTATGTAACTTTTTTACATAC
  ATTCGATACATTCAGCAGGGACTCGTGAAACAGCAGGATGTTGATCAGATGTTTTGGGAG
  GTTATGCAGTTGAGAAAAGAGATGTCATTGGCAAAGCTGGGTTATTTCAAAGAGGAACTC
  TGA
  
  Clone variation with respect to NM_022456.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022456 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCTCGTGCCGAATTC
  GGCACGAGGGCGTAGTGAGCCCGCCGCCGTGGAGTGTAGCGGAGAGGGCTCGCCGTCCTC
  CTCCGTTTCTCGCTGCTTCGGGACGCGCTCTCTGCGGCTCTGTGAGCGCCCCTGAGCGCC
  GGCAGCGGCCGCGGTGGGTTCTTCAGGTTATCTTATGATGAGGCTTTTGCTATGGCTAAT
  GATCCCTTGGAAGGCTTCCATGAAGTAAACCTTGCTTCACCTACTTCTCCGGACCTTCTT
  GGTGTGTATGAATCAGGAACTCAAGAGCAGACTACCTCACCAAGTGTCATCTACCGGCCA
  CACCCTTCAGCTTTATCCTCTGTACCTATCCAGGCAAATGCATTAGATGTTTCTGAACTT
  CCTACACAACCCGTGTATTCATCCCCCAGACGTTTAAATTGTGCGGAAATATCTAGTATC
  AGCTTTCATGTTACAGACCCAGCCCCTTGCTCTACCTCTGGAGTCACAGCTGGATTAACT
  AAATTAACTACAAGAAAGGACAACTATAATGCAGAGAGAGAGTTTTTACAGGGTGCTACT
  ATAACAGAGGCTTGCGATGGCAGTGATGATATTTTTGGGTTGAGTACTGATAGTCTGTCT
  CGTTTACGAAGCCCATCTGTTTTGGAAGTTAGAGAAAAGGGCTATGAACGATTAAAAGAA
  GAACTCGCANAAGCTCAGAGGGAACTGAAGTTAAAGATGAAGATGTGAGNAGGCTTCAAA
  GTGCGAGNATCACTTGGACAGGGATTGGAGAACTACAGCTAGTCTATTGAGAAGCTCAAA
  NATGGTGAGAGAGCAATATCAGCAGGGCACAGCGAAAACAGCTAAGAGCCAGGGAAATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022456 unedited
  ACGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTCAATCTAACATTTATTTATTTCAG
  GTTTTTTTTTTTTTTGGCAACTATAAATTACATTCACTAGTACACCTGGAATTCTTCATA
  GTGTGTTCAACTAAAGAATAAGCAAACACAGCATAGATCAGTTTAAAAGAAATCATGGTA
  CTTCTTAAAGCAATTTGCAAAAGGGGAAAAAAGTCTTAGGCTCACTCCTTGGAAATAAAT
  ATCAAGTAACCATAAAAATATTCAGCCATTTTTCAGTTATTCGGGGAGTTCAGGCATGGT
  CCCACGCAAAGCATCAAAGTTCCTCTTTGAAATAACCCAGCTTTGCCAATGACATCTCTT
  TTCTCAACTGCATAACCTCCCAAAACATCTGATCAACATCCTGCTGTTTCACGAGTCCCT
  GCTGAATGTATCGAATGTATGTAAAAAAGTTACATACAGAAGTGATCCTGTATCTGCAAA
  AAGGAGAAATATAATAATAGTTGCTTGAGTCCCCTAATTTAATTCTGTGTTTACAGGACT
  TACTCTGGCCAGTGAGAGCACATTTTTTTGGTCCTCCGCATTCAACTGCAGAAGCTTTCA
  CAAACCGGATAGGTTGTAATCCCACTGGTTCAATGCTTAAAGTATTGTTTTCCACAGCCT
  CCAGAACAGCTGAAGCCAACTCACTTTTTGAGAATGTTAAACATGGAAAGATATCTTCCT
  GGTAGATTTTGTCTAAGAAGGACACGTNCTGTCCATTGTGGGCTCATCCCTTTCCACATC
  GGATTCATTATACAGGGGATAGTCAGCCTCTTTGCAGTCTTTTACAATTGGCTGTATCAC
  ACTGAGTCCTGATGACTGCCACTCATAGCACTGCTTGAGCTTTTATTTCTGGNATGCACC
  TTTTAAAAGGTNGTCTTNCACTGCAAAGGCTCTGCGTAGTGATGTGGAAACTGACATACA
  GGTCTCATGCACTACTAGCTGAGACACAATTTNCCTGAGCTCTTTACAGTTTCTGCGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_022456
• ORF Size: 1383 bp
• Insert Size: 1840
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_022456.2, NP_071901.2
• RefSeq Size: 1855
• RefSeq ORF: 1383
• Locus ID: 117177
• Gene Summary: Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (alpha 1) has a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant alpha 2. The resulting isoform (alpha 1) has a shorter N-terminus, compared to isoform alpha 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.