GSK3 alpha (GSK3A) (NM_019884) Human Untagged Clone

CAT#: SC112599

GSK3A (untagged)-Human glycogen synthase kinase 3 alpha (GSK3A)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GSK3A
• Synonyms: DKFZp686D0638
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_019884 edited
  ATGAGCGGCGGCGGGCCTTCGGGAGGCGGCCCTGGGGGCTCGGGCAGGGCGCGGACTAGC
  TCGTTCGCGGAGCCCGGCGGCGGAGGCGGAGGAGGCGGCGGCGGCCCCGGAGGCTCGGCC
  TCCGGCCCAGGCGGCACCGGCGGCGGAAAGGCATCTGTCGGGGCCATGGGTGGGGGCGTC
  GGGGCCTCGAGCTCCGGGGGTGGACCCGGCGGCAGCGGCGGAGGAGGCAGCGGAGGCCCC
  GGCGCAGGCACTAGCTTCCCGCCGCCCGGGGTGAAGCTGGGCCGTGACAGCGGGAAGGTG
  ACCACAGTCGTAGCCACTCTAGGCCAAGGCCCAGAGCGCTCCCAAGAAGTGGCTTACACG
  GACATCAAAGTGATTGGCAATGGCTCATTTGGGGTCGTGTACCAGGCACGGCTGGCAGAG
  ACCAGGGAACTAGTCGCCATCAAGAAGGTTCTCCAGGACAAGAGGTTCAAGAACCGAGAG
  CTGCAGATCATGCGTAAGCTGGACCACTGCAATATTGTGAGGCTGAGATACTTTTTCTAC
  TCCAGTGGCGAGAAGAAAGACGAGCTTTACCTAAATCTGGTGCTGGAATATGTGCCCGAG
  ACAGTGTACCGGGTGGCCCGCCACTTCACCAAGGCCAAGTTGACCATCCCTATCCTCTAT
  GTCAAGGTGTACATGTACCAGCTCTTCCGCAGCTTGGCCTACATCCACTCCCAGGGCGTG
  TGTCACCGCGACATCAAGCCCCAGAACCTGCTGGTGGACCCTGACACTGCTGTCCTCAAG
  CTCTGCGATTTTGGCAGTGCAAAGCAGTTGGTCCGAGGGGAGCCCAATGTCTCCTACATC
  TGTTCTCGCTACTACCGGGCCCCAGAGCTCATCTTTGGAGCCACTGATTACACCTCATCC
  ATCGATGTTTGGTCAGCTGGCTGTGTACTGGCAGAGCTCCTCTTGGGCCAGCCCATCTTC
  CCTGGGGACAGTGGGGTGGACCAGCTGGTGGAGATCATCAAGGTGCTGGGAACACCAACC
  CGGGAACAAATCCGAGAGATGAACCCCAACTACACGGAGTTCAAGTTCCCTCAGATTAAA
  GCTCACCCCTGGACAAAGGTGTTCAAATCTCGAACGCCGCCAGAGGCCATCGCGCTCTGC
  TCTAGCCTGCTGGAGTACACCCCATCCTCAAGGCTCTCCCCACTAGAGGCCTGTGCGCAC
  AGCTTCTTTGATGAACTGCGATGTCTGGGAACCCAGCTGCCTAACAACCGCCCACTTCCC
  CCTCTCTTCAACTTCAGTGCTGGTGAACTCTCCATCCAACCGTCTCTCAACGCCATTCTC
  ATCCCTCCTCACTTGAGGTCCCCAGCGGGCACTACCACCCTCACCCCGTCCTCACAAGCT
  TTAACTGAGACTCCGACCAGCTCAGACTGGCAGTCGACCGATGCCACACCTACCCTCACT
  AACTCCTCCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_019884 unedited
  ACACGCAATTCGCACGAGGCCGGAGCCCAAGCCAGAGCGGCGCGGCCTGGAAGAGGCCAG
  GGCCCGGGGGAGGCGGCGGCAGCGGCGGCGGCTGGGGCAGCCCGGGCAGCCCGAGCCCCG
  CAGCCTGGGCCTGTGCTCGGCGCCATGAGCGGCGGCGGGCCTTCGGGAGGCGGCCCTGGG
  GGCTCGGGCAGGGCGCGGACTAGCTCGTTCGCGGAGCCCGGCGGCGGAGGCGGAGGAGGC
  GGCGGCGGCCCCGGAGGCTCGGCCTCCGGCCCAGGCGGCACCGGCGGCGGAAAGGCATCT
  GTCGGGGCCATGGGTGGGGGCGTCGGGGCCTCGAGCTCCGGGGGTGGACCCGGCGGCAGC
  GGCGGAGGAGGCAGCGGAGGCCCCGGCGCAGGCACTAGCTTCCCGCCGCCCGGGGTGAAG
  CTGGGCCGTGACAGCGGGAAGGTGACCACAGTCGTAGCCACTCTAGGCCAAGGCCCAGAG
  CGCTCCCAAGAAGTGGCTTACACGGACATCAAAGTGATTGGCAATGGCTCATTTGGGGTC
  GTGTACCAGGCACGGCTGGCAGAGACCAGGGAACTAGTCGCCATCAAGAAGGTTCTCCAG
  GACAAGAGGTTCAAGAACCGAGAGCTGCAGATCATGCGTAAGCTGGACCACTGCAATATT
  GTGAGGCTGAGATACTTTTTCTACTCCAGTGGCGAGAAGAAAGACGAGCTTTACCTAAAT
  CTGGTGCTGGAATATGTGCCCGAGACAGTGTACCCGGGTGGCCCGCCACTTCACCAAGGC
  CAAGTTGACCATCCCTATCCTCTATGTCAAGGTGTACATGTACCAGCTCTTCCGCAGCTT
  GGCCTACATNCACTCCNAGGGCGTGTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_019884 unedited
  TTTTTTTTTTTTTTTTTCATGCCAATAATTTATTGAACGGAGGTCTGTACACAGGCAAAC
  CTTACTGTGGAAACTAAGACATCAGGAGCTCTCTCCACTCCCCTGGCCCTCCAGGGTGGG
  GTGAGGAGGGAGTAAACCTTGGGGGCAGAGGACAGGAGGGGAGTTACAGCTGTAGGAGGG
  GCGGGGCCAGGTTGGACGGTGCGAATCGACGTTTTCTTTAAGAAAAAAATTATAACAATC
  TATTTACACCCGGGGGCCAGGGAAGGGAAAAGGAGACGGGCTGGGCTGGTTCTATTTACA
  AGGGACACAGGAGGGGAGGGGGTCTGGAGGAGGTGGAGGTCTGGGGGAGGGGAGGCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_019884
• Insert Size: 2170 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_019884.2, NP_063937.2
• RefSeq Size: 2200 bp
• RefSeq ORF: 1452 bp
• Locus ID: 2931
• Cytogenetics: 19q13.2
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Chemokine signaling pathway
• Gene Summary: 'This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011]'