RNF86 (TRIM2) (NM_015271) Human Untagged Clone

CAT#: SC112638

TRIM2 (untagged)-Human tripartite motif containing 2 (TRIM2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIM2
• Synonyms: CMT2R; RNF86
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015271, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCACAGGAGTGGCCGTTATGGAACGCAGCAGCAGCGTGCAGGGTCAAAGACAGCCGGCCCCCCATGTC
  AGTGGTCTAGGATGGCCAGTGAAGGCACCAACATCCCAAGTCCTGTGGTGCGCCAGATTGACAAGCAGTT
  TCTGATTTGCAGTATATGCCTGGAACGGTACAAGAATCCCAAGGTTCTCCCCTGTCTGCACACTTTCTGC
  GAGAGGTGCCTGCAGAACTACATTCCTGCCCACAGTTTAACCCTCTCCTGCCCAGTGTGCCGCCAGACCT
  CCATCCTGCCCGAGAAAGGGGTGGCCGCGCTCCAGAACAATTTCTTCATCACAAACCTGATGGACGTGCT
  GCAGCGAACTCCAGGCAGCAACGCTGAGGAGTCTTCCATCCTGGAGACAGTCACTGCTGTGGCTGCGGGA
  AAGCCTCTCTCTTGCCCAAACCACGATGGGAATGTGATGGAATTTTACTGCCAGTCCTGTGAGACTGCCA
  TGTGTCGGGAGTGCACGGAGGGGGAGCACGCAGAGCACCCCACAGTTCCACTCAAGGATGTGGTGGAACA
  GCACAAGGCCTCGCTCCAGGTCCAGCTGGATGCTGTCAACAAAAGGCTCCCAGAAATAGATTCTGCTCTT
  CAGTTCATCTCTGAAATCATTCATCAGTTAACCAACCAAAAGGCCAGCATCGTGGATGACATTCATTCCA
  CCTTTGATGAGCTCCAGAAGACTTTAAATGTGCGCAAGAGTGTGCTGCTTATGGAATTGGAGGTCAACTA
  TGGCCTCAAACACAAAGTCCTCCAGTCGCAGCTGGATACTCTGCTCCAGGGGCAGGAGAGCATTAAGAGC
  TGCAGCAACTTCACAGCGCAGGCCCTCAACCATGGCACGGAGACCGAGGTCCTACTGGTGAAGAAGCAGA
  TGAGCGAGAAGCTGAACGAGCTGGCCGACCAGGACTTCCCCTTGCACCCGCGGGAGAACGACCAGCTGGA
  TTTCATCGTGGAAACCGAGGGGCTGAAGAAGTCCATCCACAACCTCGGGACGATCTTAACCACCAACGCC
  GTTGCCTCAGAGACAGTGGCCACGGGCGAGGGGCTGCGGCAGACCATCATCGGGCAGCCCATGTCCGTCA
  CCATCACCACCAAGGACAAAGACGGTGAGCTGTGCAAAACCGGCAACGCCTACCTCACCGCCGAACTGAG
  CACCCCCGACGGGAGCGTGGCAGACGGGGAGATCCTGGACAACAAGAACGGCACCTATGAGTTTTTGTAC
  ACTGTCCAGAAGGAAGGGGACTTTACCCTGTCTCTGAGACTCTATGACCAGCACATCCGAGGCAGCCCGT
  TTAAGCTGAAAGTGATCCGATCCGCTGATGTGTCTCCCACCACAGAAGGCGTGAAGAGGCGCGTTAAGTC
  CCCGGGGAGCGGCCACGTCAAGCAGAAAGCTGTGAAAAGACCCGCAAGCATGTACAGCACTGGAAAACGA
  AAAGAGAATCCCATCGAAGACGATTTGATCTTTCGAGTGGGTACCAAAGGAAGAAATAAAGGAGAGTTTA
  CAAATCTTCAGGGGGTAGCTGCATCTACAAATGGAAAGATATTAATTGCAGACAGTAACAACCAATGTGT
  GCAGATATTTTCCAATGATGGCCAGTTCAAAAGTCGTTTTGGCATACGGGGACGCTCTCCGGGGCAGCTG
  CAGCGGCCCACAGGAGTGGCTGTACATCCCAGTGGGGACATAATCATTGCCGATTATGATAATAAATGGG
  TCAGCATTTTCTCCTCCGATGGGAAATTTAAGACAAAAATTGGATCAGGAAAGCTGATGGGACCCAAAGG
  AGTTTCTGTGGACCGCAATGGGCACATTATTGTTGTGGACAACAAGGCGTGCTGCGTGTTTATCTTCCAG
  CCAAACGGGAAAATAGTCACCAGGTTTGGTAGCCGAGGAAATGGGGACAGGCAGTTTGCAGGTCCCCATT
  TTGCAGCTGTAAATAGCAATAATGAGATTATTATTACAGATTTCCATAATCATTCTGTCAAGGTGTTTAA
  TCAGGAAGGAGAATTCATGTTGAAGTTTGGCTCAAATGGAGAAGGAAATGGGCAGTTTAATGCTCCAACA
  GGTGTAGCAGTGGATTCAAATGGAAACATCATTGTGGCCGACTGGGGAAACAGCAGGATCCAGGTTTTTG
  ATGGGAGTGGATCATTTTTGTCCTACATTAACACATCTGCTGACCCACTCTATGGCCCCCAAGGCCTGGC
  CCTAACTTCAGATGGTCATGTTGTGGTTGCAGACTCTGGAAATCACTGTTTCAAAGTCTATCGATACTTA
  CAGTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015271 unedited
  CCGTCACATGTGTAACCTACTCATATAGGCGGCCGCCAATCGGCACGAGGTCTGCGGGCT
  GCGGGGAGCTAAGTCCCCAGATGGCGGAGGCTGGCTCTGGTCTTCGATGCACAGGAGTGG
  CCGTTATGGAACGCAGCAGCAGCGTGCAGGGTCAAAGACAGCCGGCCCCCCATGTCAGTG
  GTCTAGGATGGCCAGTGAAGGCACCAACATCCCAAGTCCTGTGGTGCGCCAGATTGACAA
  GCAGTTTCTGATTTGCAGTATATGCCTGGAACGGTACAAGAATCCCAAGGTTCTCCCCTG
  TCTGCACACTTTCTGCGAGAGGTGCCTGCAGAACTACATTCCTGCCCACAGTTTAACCCT
  CTCCTGCCCAGTGTGCCGCCAGACCTCCATCCTGCCCGAGAAAGGGGTGGCCGCGCTCCA
  GAACAATTTCTTCATCACAAACCTGATGGACGTGCTGCAGCGAACTCCAGGCAGCAACGC
  TGAGGAGTCTTCCATCCTGGAGACAGTCACTGCTGTGGCTGCGGGAAAGCCTCTCTCTTG
  CCCAAACCACGATGGGAATGTGATGGAATTTTACTGCCAGTCCTGTGAGACTGCCATGTG
  TCGGGAGTGCACGGAGGGGGAGCACGCTGAGCACCCCACAGTTCCACTCAAGGATGTGGT
  GGCACAGCACAAGGCCTCGCTCCAGGTCCAGCTGGATGCTGTCAACAAAAGGCTCCCAGA
  CATAGATTCTGCTCTTCAGTTCATCTTTGAAATCATTCATCAGTTTACCCAACCAAAGGG
  CCAGCATCGTTGGATGACATTTATTCCACCTTTGATGAGCTCCAGAAGACTTTAAATGTG
  CGCAAGAGTGTGCTGTTTATGGAAATTGAGGTAACTATGGTCTTTAACACCAAGTCCTTC
  CGTCGCAGCTGGATACTTCTGTCN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015271 unedited
  CCGCGGGCCGCATTTTAGNATCGAGTTTTTTTTTTTTTTTTTTGAAAGCCAGAAGGCCAT
  TTTCTGACTAAAAGCCACCACCGTCATTCTTGGAAAATGGCAAAAATTAAATCTGCTTTA
  GGGCTTGCTCCACTAGGACGGCTTTAAACTGCTTAGTAAAGGAATGTGCTGAAGAGTGGC
  TGGACGAAGCTTCTGTCTTTCAGAGTGCTGCCTATTTCAATACACCAAAGATTCAGCTAT
  ATATATGTGTGTGTGTATATATATATATATATATAATACATTCTATCTTACCCTAATCAT
  GTATACATAGTCCCTTGACACCTCTACTATTCATTAAACAATGATAAATAACCATAACAT
  GCCCTTACCTGTAATGCTTTCAAGATAACACAACTTTGGTAACACTTGCTTTCTAAGGGG
  GAATCATTAATCAATCACATGCCTTTGGTTGACACCATCAGTCCTCCAAAGGGCTACTTA
  TGGCTCTCTGTCCTAGGATACTGGTGTCCTACTACATGTGCTGACATTTGCAGGAGGTAA
  AGCTTTCGCTTTCAGGAAGTCGAAGAGAAGAGACACGTGTGAAAACATGGTACATAAAAC
  ATGACTAACTTTCTTGATTACATTCCAGTGCAATGATCTGGAGTTAACAGGGCAGTTTGT
  TTCCCAAAAGGTAGCATTACTTTTGTAATATGCTTTTCAAGGCATTAGAAATTTCAGGTT
  TCCCTGAAGAAGTACTTTGTTTGCTGATACAAGGTGAGCCAAAGGGGGTGGTGAAAAGAA
  CACCACAAAAAGATCTTTGTCTAACCAGAAAGGTGAGAAATTTGACTGATACTTAGTTCT
  GACTCCAGAGGCTGCTATAGAGCTGGGATCTTTGCAGACGCCTACTTTTNCAAGTAATTA
  TATTTAGTGTGATACCAAAAAGNCCAGAGTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015271
• ORF Size: 2235 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015271.2, NP_056086.1
• RefSeq Size: 6757
• RefSeq ORF: 2235
• Locus ID: 23321
• Domains: zf-B_box, NHL, Filamin, RING, BBC
• Gene Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
  Transcript Variant: This variant (1) encodes the longest isoform (1).