POT1 (NM_015450) Human Untagged Clone

CAT#: SC112647

POT1 (untagged)-Human protection of telomeres 1 homolog (S. pombe) (POT1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POT1
• Synonyms: CMM10; GLM9; HPOT1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112647 sequence for NM_015450 edited (data generated by NextGen Sequencing)
  ATGTCTTTGGTTCCAGCAACAAATTATATATATACACCCCTGAATCAACTTAAGGGTGGT
  ACAATTGTCAATGTCTATGGTGTTGTGAAGTTCTTTAAGCCCCCATATCTAAGCAAAGGA
  ACTGATTATTGCTCAGTTGTAACTATTGTGGACCAGACAAATGTAAAACTAACTTGCCTG
  CTCTTTAGTGGAAACTATGAAGCCCTTCCAATAATTTATAAAAATGGAGATATTGTTCGC
  TTTCACAGGCTGAAGATTCAAGTATATAAAAAGGAGACTCAGGGTATCACCAGCTCTGGC
  TTTGCATCTTTGACGTTTGAGGGAACTTTGGGAGCCCCTATCATACCTCGCACTTCAAGC
  AAGTATTTTAACTTCACTACTGAGGACCACAAAATGGTAGAAGCCTTACGTGTTTGGGCA
  TCTACTCATATGTCACCGTCTTGGACATTACTAAAATTGTGTGATGTTCAGCCAATGCAG
  TATTTTGACCTGACTTGTCAGCTCTTGGGCAAAGCAGAAGTGGACGGAGCATCATTTCTT
  CTAAAGGTATGGGATGGCACCAGGACACCATTTCCATCTTGGAGAGTCTTAATACAAGAC
  CTTGTTCTTGAAGGTGATTTAAGTCACATCCATCGGCTACAAAATCTGACAATAGACATT
  TTAGTCTACGATAACCATGTTCATGTGGCAAGATCTCTGAAGGTTGGAAGCTTTCTTAGA
  ATCTATAGCCTTCATACCAAACTTCAATCAATGAATTCAGAGAATCAGACAATGTTAAGT
  TTAGAGTTTCATCTTCATGGAGGTACCAGTTACGGTCGGGGAATCAGGGTCTTGCCAGAA
  AGTAACTCTGATGTGGATCAACTGAAAAAGGATTTAGAATCTGCAAATTTGACAGCCAAT
  CAGCATTCAGATGTTATCTGTCAATCAGAACCTGACGACAGCTTTCCAAGCTCTGGATCA
  GTATCATTATACGAGGTAGAAAGATGTCAACAGCTATCTGCTACAATACTTACAGATCAT
  CAGTATTTGGAGAGGACACCACTATGTGCCATTTTGAAACAAAAAGCTCCTCAACAATAC
  CGCATCCGAGCAAAATTGAGGTCATATAAGCCCAGAAGACTATTTCAGTCTGTTAAACTT
  CATTGCCCTAAATGTCATTTGCTGCAAGAAGTTCCACATGAGGGCGATTTGGATATAATT
  TTTCAGGATGGTGCAACTAAAACCCCAGATGTCAAGCTACAAAATACATCATTATATGAT
  TCAAAAATCTGGACCACTAAAAATCAAAAAGGACGAAAAGTAGCAGTTCATTTTGTGAAA
  AATAATGGTATTCTCCCGCTTTCAAATGAATGTCTACTTTTGATAGAAGGAGGTACACTC
  AGTGAAATTTGCAAACTCTCGAACAAGTTTAATAGTGTAATTCCTGTGAGATCTGGCCAC
  GAAGACCTGGAACTTTTGGACCTTTCAGCACCATTTCTTATACAAGGAACAATACATCAC
  TATGGATGTAAACAGTGTTCTAGTTTGAGATCCATACAAAATCTAAATTCCCTGGTTGAT
  AAAACATCGTGGATTCCTTCTTCTGTGGCAGAAGCACTGGGTATTGTACCCCTCCAATAT
  GTGTTTGTTATGACCTTTACACTTGATGATGGAACAGGAGTACTAGAAGCCTATCTCATG
  GATTCTGACAAATTCTTCCAGATTCCAGCATCAGAAGTTCTGATGGATGATGACCTTCAG
  AAAAGTGTGGATATGATCATGGATATGTTTTGTCCTCCAGGAATAAAAATTGATGCATAT
  CCGTGGTTGGAATGCTTCATCAAGTCATACAATGTCACAAATGGAACAGATAATCAAATT
  TGCTATCAGATTTTTGACACCACAGTTGCAGAAGATGTAATCTAA
  
  Clone variation with respect to NM_015450.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015450 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGCAAGTTGTCAGAT
  TCCCTAGTTGAATTTGCTTTGGACATCAGTGTGAAGCAGAACTGATATGCCACTTGAATT
  AATAAAGGAAGTCAATGGGGTGCCTGAAGTTCAGCCGCTGAGTAAATTACATAAAGTAGA
  TTTCGGATCCCTACAGCCAGGTTACAATTATAGCAAGAAATATATTCAGGGAAAACTTTC
  ACTTATCTCTTCTTTAACTTATCGTGGAAATAAAACAGCTGTTTTGCAGATTGGACTACA
  AGGACACCATTGCAGTGGCTAGATTTATTGTTTTTTTAGCTTCTTCATCTACAAGCAGAG
  ATGGTAAACCTTGCATATTTTTGAAAGCATTTGAAGACCTCAAATCAACTGTTTATGTTT
  ATGTCAAATCTTTAAGAGATTTTTCTACAGAATCAATGTCTTTGGTTCCAGCAACAAATT
  ATATATATACACCCCTGAATCAACTTAAGGGTGGTACAATTGTCAATGTCTATGGTGTTG
  TGAAGTTCTTTAAGCCCCCATATCTAAGCAAAGGAACTGATTATTGCTCAGTTGTAACTA
  TTGTGGACCAGACAAATGTAAAACTAACTTGCCTGCTCTTTAGTGGAAACTATGAAGCCC
  TTCCAATAATTTATAAAAATGGAGATATTGTTCGCTTTCACAGGCTGAAGATTAAGTATA
  TAAAAAGGAGACTCAGGNTATCACCAGCTCTGGCTTTGCATCTTTGACGTTTGAGGGAAC
  TTGGGNAGCCCTATCATACCTCGCACTTCAAGCAGTATTTTAACTTCACTACTGAGACAC
  ANATGTAGAAGCCTTACTGTTTGGGCACTACTATATGCACCGTCTGGACATACTAAATGT
  GGGATGTCACCAAGCGTTTTTGACTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015450 unedited
  TCTATGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAACATTATA
  AATCTGACCACTTTTATTAGGTTGAGGTGAAATAGAGAAATCTCTACTATCCTGGAGAGA
  AACAAGCAATAAAACCATGTATTACAAGTTTAAAGAAATGAATTTATCCTAAAATCATCA
  GTATCAGCACCCCAACAAAGCAACTTTGCCATTTCTACTTAAAGTACACTGTAGCTTGAT
  CAGACACTTATCTCAGCAGTACTTGTTTAAGCAGGTCTCTTTGTACAAAAGCAAAACAGA
  AAGCAAAACAAAATCCATAGCCATTATTTACCTTGCACCCAGTAAAAGCCAAGAGATTTA
  AGGTAAGGACATTTTCTAATCCCATACCCATGCTAACATCATCAACATTGCTGATACAAA
  ACTCAGGTCAGGAAAAGAAGCTCAAACAGGGAAGGTGAGTGGCAACATTTTATGTATGCT
  AAATTGGATGGCAATATTAGATTACATCTTCTGCAACTGTGGTGTCAAAAATCTGATAGC
  AAATTTGATTATCTGTTCCATTTGTGACATTGTATGACTTGATGAAGCATTCCAACCACG
  GATATGCATCAATTTTTATTCCTGGAGGACAAAACATATCCATGATCATATCCACACTTT
  TCTGAAGGTCATCATCCATCAGAACTTCTGATGCTGGAATCTGGAAGAATTTGTCAGAAT
  CCATGAGATAGGCTTCTAGTACTCCTGTTCCATCATCAAGTGTAAGGTCATAACAACACA
  TATGGNAGGGGTACATACCCAGTGCTTCTGCCACAGAGAAGGATCCACCGATGTTTATCA
  CCANGGAATTTAGATTTGNATNGATCTCAAACTAAACACTGNTACATCCTAGGGATGNAT
  TGGTCCTTGGATAAAAATGGGGCTGAAAGGTNCAAAGGTTCAGTNCTTCTGGGCCGATCT
  TCACGGATACACTTATAAACTTGTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015450
• ORF Size: 1905 bp
• Insert Size: 2930
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015450.1, NP_056265.1
• RefSeq Size: 2631
• RefSeq ORF: 1905
• Locus ID: 25913
• Gene Summary: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1).