EBP50 (SLC9A3R1) (NM_004252) Human Untagged Clone

CAT#: SC112667

SLC9A3R1 (untagged)-Human solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (SLC9A3R1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC9A3R1
• Synonyms: EBP50; NHERF; NHERF-1; NHERF1; NPHLOP2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_004252 edited
  GGGCGGCCGCGAATTCGCACGAGGGTCTGTGCTCCTCTCTCGGCTCCTCGCGGCTCGCGG
  CGGCCGACGGTTCCTGGGACACCTGCTTGCTTGGCCCGTCCGGCGGCTCAGGGCTTCTCT
  GCTGCGCTCCCGGTTCGCTGGACGGGAAGAAGGGCTGGGCCGTCCCGTCCCGTCCCCATC
  GGAACCCCAAGTCGCGCCGCTGACCCGTCGCAGGGCGAGATGAGCGCGGACGCAGCGGCC
  GGGGCGCCCCTGCCCCGGCTCTGCTGCCTGGAGAAGGGTCCGAACGGCTACGGCTTCCAC
  CTGCACGGGGAGAAGGGCAAGTTGGGCCAGTACATCCGGCTGGTGGAGCCCGGCTCGCCG
  GCCGAGAAGGCGGGGCTGCTGGCGGGGGACCGGCTGGTGGAGGTGAACGGCGAAAACGTG
  GAGAAGGAGACCCACCAGCAGGTGGTGAGCCGCATCCGCGCCGCACTCAACGCCGTGCGC
  CTGCTGGTGGTCGACCCCGAGACGGACGAGCAGCTGCAGAAGCTCGGCGTCCAGGTCCGA
  GAGGAGCTGCTGCGCGCCCAGGAAGCGCCGGGGCAGGCCGAGCCGCCGGCCGCCGCCGAG
  GTGCAGGGGGCTGGCAACGAAAATGAGCCTCGCGAGGCCGACAAGAGCCACCCGGAGCAG
  CGCGAGCTTCGGCCTCGGCTCTGTACCATGAAGAAGGGCCCCAGTGGCTATGGCTTCAAC
  CTGCACAGCGACAAGTCCAAGCCAGGCCAGTTCATCCGGTCAGTGGACCCAGACTCCCCG
  GCTGAGGCTTCAGGGCTCCGGGCCCAGGATCGCATTGTGGAGGTGAACGGGGTCTGCATG
  GAGGGGAAGCAGCATGGGGACGTGGTGTCCGCCATCAGGGCTGGCGGGGACGAGACCAAG
  CTGCTGGTGGTGGACAGGGAAACTGACGAGTTCTTCAAGAAATGCAGAGTGATCCCATCT
  CAGGAGCACCTGAATGGTCCCCTGCCTGTGCCCTTCACCAATGGGGAGATACAGAAGGAG
  AACAGTCGTGAAGCCCTGGCAGAGGCAGCCTTGGAGAGCCCCAGGCCAGCCCTGGTGAGA
  TCCGCCTCCAGTGACACCAGCGAGGAGCTGAATTCCCAAGACAGCCCCCCAAAACAGGAC
  TCCACAGCGCCCTCGTCTACCTCCTCCTCCGACCCCATCCTAGACTTCAACATCTCCCTG
  GCCATGGCCAAAGAGAGGGCCCACCAGAAACGCAGCAGCAAACGGGCCCCGCAGATGGAC
  TGGAGCAAGAAAAACGAACTCTTCAGCAACCTCTGAGCGCCCTGCTGCCACCCAGTGACT
  GGCAGGGCCGAGCCAGCATTCCACCCCACCTTTTTCCTTCTCCCCAATTACTCCCCTGAA
  TCAATGTACAAATCAGCACCCACATCCCCTTTCTTGACAAATGATTTTTCTAGAGAACTA
  TGTTCTTCCCTGACTTTAGGGAAGGTGAATGTGTTCCCGTCCTCCCGCAGTCAGAAAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004252 unedited
  GTTTCCGTTTTGTAATACGACTTACTATAGGGCGGCCGCGCAATTCGCACGAGGGTCTGT
  GCTCCTCTCTCGGCTCCTCGCGGCTCGCGGCGGCCGACGGTTCCTGGGACACCTGCTTGC
  TTGGCCCGTCCGGCGGCTCAGGGCTTCTCTGCTGCGCTCCCGGTTCGCTGGACGGGAAGA
  AGGGCTGGGCCGTCCCGTCCCGTCCCCATCGGAACCCCAAGTCGCGCCGCTGACCCGTCG
  CAGGGCGAGATGAGCGCGGACGCAGCGGCCGGGGCGCCCCTGCCCCGGCTCTGCTGCCTG
  GAGAAGGGTCCGAACGGCTACGGCTTCCACCTGCACGGGGAGAAGGGCAAGTTGGGCCAG
  TACATCCGGCTGGTGGAGCCCGGCTCGCCGGCCGAGAAGGCGGGGCTGCTGGCGGGGGAC
  CGGCTGGTGGAGGTGAACGGCGAAAACGTGGAGAAGGAGACCCACCAGCAGGTGGTGAGC
  CGCATCCGCGCCGCACTCAACGCCGTGCGCCTGCTGGTGGTCGACCCCGAGACGGACGAG
  CAGCTGCAGAAGCTCGGCGTCCAGGTCCGAGAGGAGCTGCTGCGCGCCCAGGAAGCGCCG
  GGGCAGGCCGAGCCGCCGGCCGCCGCCCGAGTGCATGGGGCTGGCAACGATAATGAGCCT
  TGCGAGGCCGACAAGAGCCACCCGGAGCAGCGCGAGCTTCGGCCTCGGCTCTGTACCATG
  AAAGAGGGCCCCCATTGGCTATGGCTTCAACCTGCCCAGCGACCAGTTCAAGCCAGGCCC
  ATTCATCCCGTCCGTGGACCCCAAACTCCCCGGCTGGAGCTTCAGGGCTCCGGGCCCAGG
  ATCGCTTGGGGAGGTGACCGCGGTCTGCTGGGGGGGAAGCCAGCTGGGGACTTGTGGTCC
  GCCTTCAGGGCTGGCGGGACCAAACCAACA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004252 unedited
  GCCGCAATTAGAGTCGAGNNTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGG
  AGGAACCAACTGAATTTCTGAAAGTGTTTCCTTACAATGGGGGGACCTGGCTTAAGGATG
  GGCAGGGGTAACCAAACCCTTCCCGTGCTGCCCAATTTGCTGAGGGGGGGAGTAGGAACA
  AAAGTTTAAAGGTGAGGCCACTGCCATGCCCTGGATGTAACAACCAGGAAAATCATGTTT
  ATCAAGGAAACAAAAATTCCTTTAAACTCTGCAATACTGCACTTTTAACAAAAATCAAAT
  GAAAACAAGACGTGTTTGCCACAGGTCTTAAGATAACAAATGCCCTGTCCACTGAAAACG
  GGAGTTCTGTAGTCAAAGTTCTTTGATCAACCCTGGACCCATTTATTACATGGGGGACGA
  ACGGATGGCGTTCCCCTCCCTGCTCACCTTATCTCCCTGTTTTCTCCCTTTTTCCGTCCC
  TTCCTTGCTCCTCCCTTCTCCTTTCTCTCTTCCCTCCTTCCTTGTTTCTTTCTGCCCTCT
  CACTTTCCTCCTTCCTCTCTCGATATTCTCTCCTTTTTCTCTCTTCCCTATCTCTCTTTC
  CCCCCTCCACCATTTCCTTTCTCCCTCTTCCTCCCCCCTTATTCTCCTGCATCCCCATTA
  TTTCCTCTTCTTCTCCCTCTTTTCTTCCCAGACTTTATACCCCTTCACGTCATTTCTAAT
  TCATTCTCTTTCTCTATATCCCTACTTTACCTTCTCACTATTTCTTTTCCCCCCCCCTCT
  TTACCCCATTCTTATTCCCCCCTTCTTTCCTTCTTTCCCCTTTTCCTTCCTTCCTCTTCC
  TTCCTTCATCCCCACCCCTTTTTCTACCCCCTTCCCTTTGTCCCTCCCTTTCCTTTCCCC
  TTTTTCTTCTCTCATCTTCCTTTTCCGATCCCATCCCCTCTCCTTCTTTTTCCTTCTCCT
  TCTTTTTCCTCCCCTTTCCACTCTCCCCCTTTCTTCCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004252
• ORF Size: 1077 bp
• Insert Size: 2060
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004252.1, NP_004243.1
• RefSeq Size: 2000
• RefSeq ORF: 1077
• Locus ID: 9368
• Domains: PDZ
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer. [provided by RefSeq, Sep 2009]