GPR37 (NM_005302) Human Untagged Clone

CAT#: SC112677

GPR37 (untagged)-Human G protein-coupled receptor 37 (endothelin receptor type B-like) (GPR37)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GPR37
• Synonyms: EDNRBL; hET(B)R-LP; PAELR
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112677 sequence for NM_005302 edited (data generated by NextGen Sequencing)
  ATGCGAGCCCCGGGCGCGCTTCTCGCCCGCATGTCGCGGCTACTGCTTCTGCTACTGCTC
  AAGGTGTCTGCCTCTTCTGCCCTCGGGGTCGCCCCTGCGTCCAGAAACGAAACTTGTCTG
  GGGGAGAGCTGTGCACCTACAGTGATCCAGCGCCGCGGCAGGGACGCCTGGGGACCGGGA
  AATTCTGCAAGAGACGTTCTGCGAGCCCGAGCACCCAGGGAGGAGCAGGGGGCAGCGTTT
  CTTGCGGGACCCTCCTGGGACCTGCCGGCGGCCCCGGGCCGTGACCCGGCTGCAGGCAGA
  GGGGCGGAGGCGTCGGCAGCCGGACCCCCGGGACCTCCAACCAGGCCACCTGGCCCCTGG
  AGGTGGAAAGGTGCTCGGGGTCAGGAGCCTTCTGAAACTTTGGGGAGAGGGAACCCCACG
  GCCCTCCAGCTCTTCCTTCAGATCTCAGAGGAGGAAGAGAAGGGTCCCAGAGGCGCTGGC
  ATTTCCGGGCGTAGCCAGGAGCAGAGTGTGAAGACAGTCCCCGGAGCCAGCGATCTTTTT
  TACTGGCCAAGGAGAGCCGGGAAACTCCAGGGTTCCCACCACAAGCCCCTGTCCAAGACG
  GCCAATGGACTGGCGGGGCACGAAGGGTGGACAATTGCACTCCCGGGCCGGGCGCTGGCC
  CAGAATGGATCCTTGGGTGAAGGAATCCATGAGCCTGGGGGTCCCCGCCGGGGAAACAGC
  ACGAACCGGCGTGTGAGACTGAAGAACCCCTTCTACCCGCTGACCCAGGAGTCCTATGGA
  GCCTACGCGGTCATGTGTCTGTCCGTGGTGATCTTCGGGACCGGCATCATTGGCAACCTG
  GCGGTGATGTGCATCGTGTGCCACAACTACTACATGCGGAGCATCTCCAACTCCCTCTTG
  GCCAACCTGGCCTTCTGGGACTTTCTCATCATCTTCTTCTGCCTTCCGCTGGTCATCTTC
  CACGAGCTGACCAAGAAGTGGCTGCTGGAGGACTTCTCCTGCAAGATCGTGCCCTATATA
  GAGGTCGCTTCTCTGGGAGTCACCACCTTCACCTTATGTGCTCTGTGCATAGACCGCTTC
  CGTGCTGCCACCAACGTACAGATGTACTACGAAATGATCGAAAACTGTTCCTCAACAACT
  GCCAAACTTGCTGTTATATGGGTGGGAGCTCTATTGTTAGCACTTCCAGAAGTTGTTCTC
  CGCCAGCTGAGCAAGGAGGATTTGGGGTTTAGTGGCCGAGCTCCGGCAGAAAGGTGCATT
  ATTAAGATCTCTCCTGATTTACCAGACACCATCTATGTTCTAGCCCTCACCTACGACAGT
  GCGAGACTGTGGTGGTATTTTGGCTGTTACTTTTGTTTGCCCACGCTTTTCACCATCACC
  TGCTCTCTAGTGACTGCGAGGAAAATCCGCAAAGCAGAGAAAGCCTGTACCCGAGGGAAT
  AAACGGCAGATTCAACTAGAGAGTCAGATGAACTGTACAGTAGTGGCACTGACCATTTTA
  TATGGATTTTGCATTATTCCTGAAAATATCTGCAACATTGTTACTGCCTACATGGCTACA
  GGGGTTTCACAGCAGACAATGGACCTCCTTAATATCATCAGCCAGTTCCTTTTGTTCTTT
  AAGTCCTGTGTCACCCCAGTCCTCCTTTTCTGTCTCTGCAAACCCTTCAGTCGGGCCTTC
  ATGGAGTGCTGCTGCTGTTGCTGTGAGGAATGCATTCAGAAGTCTTCAACGGTGACCAGT
  GATGACAATGACAACGAGTACACCACGGAACTCGAACTCTCGCCTTTCAGTACCATACGC
  CGTGAAATGTCCACTTTTGCTTCTGTCGGAACTCATTGCTGA
  
  Clone variation with respect to NM_005302.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005302 unedited
  TACTATATGGCGGCCGCGAATTCCCGGGATGGGGTTGGAATCCCGCTTCTCCTCGGCAGC
  AGTAGGCTCGCAAGTCGCTGGGGTTAGGTGGGGCAAGGGTTTCGCCGGCGCATCAGCGCT
  GCTTCGGACTGTTTGCAACGTGTTTCCAGCGAGCTGGGAGCGGGGTTGTGACTGCGAGTC
  GTCTGGGGGAGGGGGACTTGTTTTTCTTTTCCTCTAGAGACCTCGGCTTGCAACTGGATC
  AAACGCTGTCGAAAGGATGTAAATAGGCAGAGCAACTGTTACCAAGAAGGCCACCACCCC
  CACCCAAAGGCAGTGAGGAGTGTGGGGCTTCGTCTGGGCTCCCCCGAGTCTCAACAGTAA
  TCAACAGTCAGGTGTTGATTGCAACTTTTCAAGGTCAGCCACCGGGAGTAGCCTATTCCC
  TCTAGGAACCTTGGAGGGCATACCTTGCTGGGACTCAACTTGGCTGAGAAATGCACAAGA
  TGCCAAAGGAGGAAGGATTATAGGGGGCGTGTGTGTGACCCCCAAGACCGATCTTCCGCT
  ATCACCCTAATCTCCGGTTCCCCGCTACCCGGGCGGGGGTGAGTATGTGACATGTGCCTA
  ACTCTCAGCAGCAACTTCGGCAGCAGGTGTCGATCCTAACTAAGCAGGAGCTGCGGCTGC
  CGGGTGTGCCCTCACCAAGCCATGCGAGCCCCGGGCGCGCTTCTCGCCCGCATGTCGCGG
  CTACTGCTTCTGCTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005302 unedited
  AAAAGACATTGGGGGCGGGCCAAACTCCGGGCCAGGNGATGGCAATGGGGGAGGGGCTCA
  ACAGGGACTGCACCCGGGCTCTGCTCGGAACCGCCTATGACCGCGGCCCGCCCCCACCAA
  AAAAAAAACCCCCCCCCCACCCCCCCCCCCCCCCCCCCCCCTTCCTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  AAAAAAAAAAAAGGTTTTTTTTTTTGGGGCCTTTTTGGGAAGGCTTCCAAGTCAAAATCC
  CCCCAAAAAACCATAAAAAAAATTTTTTTAACCCCACCTCAAATTTAAAAAACCCCAAAA
  AACCCCTTTTTTTAAAAAAAAAAAAAAAATTTTTTTTTTTAAAAAAAAAAAAAACCTTCC
  CATTTTTAAATTAAGTTGCAAAAATTTTTTTAAAAAAAAATTTTCCCCCCCCCCCCAAAA
  AAAAAATCAAAAATTTTGGGCCTTTCCTTTTTTTTTAAAAAAAAAAAAGAAAATTTTTTT
  TACAAGCCCATATTTATTTTGGAAATCCCCTTTCCCCGGAATAAAAATTTCTCTCTTTTA
  GGGTTTCTTTTTTGCCTTTTCCCCCGGGGGGGGAAAATTTGTATTATAAACTTTTCCGGG
  GGGTGTGGAAAACCCCAAAAAATTTTTTCGCCCCCCCCAAATGTTTCTCCCCTTTCCCCA
  TGGGGTTTCCCCCCAAAACCAAAAAGGGGGTCTTTTCCCGCCCCTTTTTTTTTCTGGGGG
  GGGGAGAAATTTTTTCTTTTCTCGGGGGGGGGCCCCCCTTTTCTTNNNNNNCCCCCCCCN
  NGGCCGCCCCCNAAAAAAAACAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_005302
• Insert Size: 3000 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005302.2, NP_005293.1
• RefSeq Size: 3058 bp
• RefSeq ORF: 1842 bp
• Locus ID: 2861
• Cytogenetics: 7q31.33
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Parkinson's disease
• Gene Summary: 'This gene is a member of the G protein-coupled receptor family. The encoded protein contains seven transmembrane domains and is found in cell and endoplasmic reticulum membranes. G protein-coupled receptors are involved in translating outside signals into G protein mediated intracellular effects. This gene product interacts with Parkin and is involved in juvenile Parkinson disease. [provided by RefSeq, Oct 2012]'