WFDC1 (NM_021197) Human Untagged Clone

CAT#: SC112956

WFDC1 (untagged)-Human WAP four-disulfide core domain 1 (WFDC1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WFDC1
• Synonyms: PS20
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112956 sequence for NM_021197 edited (data generated by NextGen Sequencing)
  ATGCCTTTAACCGGCGTGGGGCCGGGCAGCTGCAGGAGGCAGATCATCCGGGCTCTGTGC
  CTCTTGCTACTTCTCCTCCACGCCGGCTCTGCCAAGAATATCTGGAAACGGGCATTGCCT
  GCGAGGCTGGCCGAGAAATCCCGTGCCGAGGAGGCGGGCGCGCCCGGCGGCCCCCGGCAG
  CCCCGAGCAGACCGCTGCCCGCCGCCTCCGCGGACGCTGCCCCCCGGCGCCTGCCAGGCC
  GCGCGCTGTCAGGCGGACTCCGAGTGCCCGCGGCACCGGCGCTGCTGCTACAACGGATGC
  GCCTACGCCTGCCTAGAAGCTGTGCCGCCCCCGCCAGTCTTAGACTGGCTGGTGCAGCCG
  AAACCTCGATGGCTTGGTGGCAATGGCTGGCTCCTGGATGGCCCTGAGGAGGTGTTACAA
  GCAGAGGCGTGCAGCACCACGGAGGATGGGGCCGAACCCCTGCTCTGTCCCTCGGGCTAT
  GAGTGCCACATCCTGAGCCCAGGTGACGTGGCCGAAGGTATCCCCAACCGTGGGCAGTGC
  GTCAAGCAGCGCCGGCAAGCAGATGGGCGAATCCTACGACACAAACTTTACAAAGAATAT
  CCAGAAGGTGACTCAAAGAATGTGGCAGAACCTGGAAGGGGACAACAGAGGCACTTTCAG
  TAA
  
  Clone variation with respect to NM_021197.2
  650 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021197 unedited
  AAATGTACAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACCAGGACAGGC
  CACTCCCGGCCACGTCTCCAAGCAAGCCGGTGCCCCCTCCTCCTGCTGCCACCGCCCACT
  GAGCTGCCTGGGCTGCAGACGCCCTGGTCGGAGCGTCTGGGGCCAGATGTTATAGGGCAA
  GCTAAAAATAACCGGGCAGGCCAGCCACCATCGAGGAAGGGGCATGTGCTGGACGCGGAC
  ACATGATCCGAGGGACCCTGCTGGGTGGAACTAAGAAAGTCCAGCAGACTGTGCATGCTC
  CTGTCCCCACTCACAGGCCCACGCAGCGAGGGGGGCCCCTCTTCTGTGTGCGTCTGGAAG
  GTCGCTGCCCAGGGAGGAAATGCCTTTAACCGGCGTGGGGCCGGGCAGCTGCAGGAGGCA
  GATCATCCGGGCTCTGTGCCTCTTGCTACTTCTCCTCCACGCCGGCTCTGCCAAGAATAT
  CTGGAAACGGGCATTGCCTGCGAGGCTGGCCGAGAAATCCCGTGCCGAGGAGGCGGGCGC
  GCCCGGCGGCCCCCGGCAGCCCCGAGCAGACCGCTGCCCGCCGCCTCCGCGGACGCTGCC
  CCCCGGCGCCTGCCAGGCCGCGCGCTGTCAGGCGGACTCCGAGTGCCCGCGGCACCGGCG
  CTGCTGCTACAACGGATGCGCCTACGCCTGCCTAGAAGCTGTGCCGCCCCCGCCAGTCTT
  AGACTGGCTGGTGCAGCCGAAACCTCGATGGCTTGGTGGCAATGGCTGGCTCCTGGATGG
  CCTGAAGGAGGTGTTACAGCCAGAGCGTGCAGCACACGGAGGATGGGGGCCGACCCCTGC
  TCTGCCCTCGGCTATTAGGCCACACCTGACCCAGTGACGGGCCCGAAGGATCCAACCTGG
  GCAGAGCG
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021197
• ORF Size: 663 bp
• Insert Size: 1600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021197.2, NP_067020.2
• RefSeq Size: 1396
• RefSeq ORF: 663
• Locus ID: 58189
• Domains: WAP
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform.