TRIB3 (NM_021158) Human Untagged Clone

CAT#: SC112991

TRIB3 (untagged)-Human tribbles homolog 3 (Drosophila) (TRIB3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRIB3
• Synonyms: C20orf97; NIPK; SINK; SKIP3; TRB3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_021158 edited
  ATGCGAGCCACCCCTCTGGCTGCTCCTGCGGGTTCCCTGTCCAGGAAGAAGCGGTTGGAG
  TTGGATGACAACTTAGATACCGAGCGTCCCGTCCAGAAACGAGCTCGAAGTGGGCCCCAG
  CCCAGACTGCCCCCCTGCCTGTTGCCCCTGAGCCCACCTACTGCTCCAGATCGTGCAACT
  GCTGTGGCCACTGCCTCCCGTCTTGGGCCCTATGTCCTCCTGGAGCCCGAGGAGGGCGGG
  CGGGCCTACCAGGCCCTGCACTGCCCTACAGGCACTGAGTATACCTGCAAGGTGTACCCC
  GTCCAGGAAGCCCTGGCCGTGCTGGAGCCCTACGCGCGGCTGCCCCCGCACAAGCATGTG
  GCTCGGCCCACTGAGGTCCTGGCTGGTACCCAGCTCCTCTACGCCTTTTTCACTCGGACC
  CATGGGGACATGCACAGCCTGGTGCGAAGCCGCCACCGTATCCCTGAGCCTGAGGCTGCC
  GTGCTCTTCCGCCAGATGGCCACCGCCCTGGCGCACTGTCACCAGCACGGTCTGGTCCTG
  CGTGATCTCAAGCTGTGTCGCTTTGTCTTCGCTGACCGTGAGAGGAAGAAGCTGGTGCTG
  GAGAACCTGGAGGACTCCTGCGTGCTGACTGGGCCAGATGATTCCCTGTGGGACAAGCAC
  GCGTGCCCAGCCTACGTGGGACCTGAGATACTCAGCTCACGGGCCTCATACTCGGGCAAG
  GCAGCCGATGTCTGGAGCCTGGGCGTGGCGCTCTTCACCATGCTGGCCGGCCACTACCCC
  TTCCAGGACTCGGAGCCTGTCCTGCTCTTCGGCAAGATCCGCCGCGGGGCCTACGCCTTG
  CCTGCAGGCCTCTCGGCCCCTGCCCGCTGTCTGGTTCGCTGCCTCCTTCGTCGGGAGCCA
  GCTGAACGGCTCACAGCCACAGGCATCCTCCTGCACCCCTGGCTGCGACAGGACCCGATG
  CCCTTAGCTCCAACCCGATCCCATCTCTGGGAGGCTGCCCAGGTGGTCCCTGATGGACTG
  GGGCTGGACGAAGCCAGGGAAGAGGAGGGAGACAGAGAAGTGGTTCTGTATGGCTAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021158 unedited
  NGGTTCACATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGTGCGAT
  CCCGGGCCCGAGGGCATCAGACGGCGGCTGATTAGCTCCGGTTTGCATCACCCGGACCGG
  GGGATTAGCTCCGGTTTGCATCACCCGAACCGGGGGATTAGCTCCGGTTTGCATCACCCG
  GACCGGGGGCCGGGCGCGCACGAGACTCGCAGCGGAAGTGGAGGCGGCTCCGCGTGCGTC
  CGCTGCTAGGACCCGGGCAGGGCTGGAGCTGGGCTGGGATCCCGAGCTCGGCAGCAGCGC
  AGCGGGCCGGCCCACCTGCTGGTGCCCTGGAGGCTCTGAGCCCCGGCGGCGCCCGGGCCC
  ACGCGGAACGACGGGGCGAGATGCGAGCCACCCCTCTGGCTGCTCCTGCGGGTTCCCTGT
  CCAGGAAGAAGCGGTTGGAGTTGGATGACAACTTAGATACCGAGCGTCCCGTCCAGAAAC
  GAGCTCGAAGTGGGCCCCAGCCCAGACTGCCCCCCTGCCTGTTGCCCCTGAGCCCACCTA
  CTGCTCCAGATCGTGCAACTGCTGTGGCCACTGCCTCCCGTCTTGGGCCCTATGTCCTCC
  TGGAGCCCGAGGAGGGGCGGGCGGGCCTACCAGGCCCTGCACTGCCCTACAGGCACTGAG
  TATACCTGCAAGGTGTACCCCGTCCAGGAAGCCCTGGCCGTGCTGGAGCCCTACGCGCGG
  CTGCCCCCGCACAAGCATGTGGCTCGGCCCACTGAGGTCCTGGCTGGTACCCAGCTCCTC
  TACGCCTTTTTCACTCGGACCCATGGNGACATGCACAGCCTGGTGCGAAGCCGCCACCGT
  ATCCCTGAGCCTGAGGCTGCCGTGCTCTTCCGCCAGATGCCACCGCCCTGGCGCACTGTA
  CCAGCACCGTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021158 unedited
  AAGGCCGCACGTGAGAGTCGAGTTTTTTTCTTTTTTTTTTATTTCATAATTCTCCTTTAT
  TAGGCACAGGTAAACATACATACTCATGGTATCCAAAACCTAGAGTATGGACCTGGGATT
  GTGGACCCCAAGTGTCCCCAGAAGAGTCCCACCTGGGACTTTCCAGGTGGCCACAGGACA
  GACCCTGCCTAATCCTGTCCCTCAACCTTGGTGCTCAGGTCAGAAGCCCCATGGTTGACA
  GGCCTGGACCCTCATTCCAGAACAGTCTTGAGTTAGACAAGAACTAGCCTCATAGTTTGG
  ATTCTTATCTCTGGCCCAAATCCCAGGCTTAGGCCTGGAAGGAGAATCTCTTAATCAAGA
  GGACAGAGATGCTGGGAACACAGTTCCCAGAGTGAGCTGGGCTTGGGTCCTGAGTTGCAG
  GGGAGAGGCCTAGAGCCTTTGGCACAGGGATACCTCCCTTTCTCTGAAAAGGTACAAGAT
  ACAAAGGCAGCTGGTTTGTTTGTGAAAGGGATTGTCCTTGGACAGAGGTGCCTGAGCACC
  AGCATCAGTGGAGGCCGACACTGGTACAAAGTGTACCCAGTGTAGACAGTGACCTATGGT
  CATGGAAAAGTGCTGTCACCTCCAGGATGCCAGCTTGTCCTCTCTGCGAGCAGGGAACAT
  TGGCTCCTTTGCTCACTGCTGGGACTCCCAGCACCGGAAACAGGCCTTGGCACCTGATAA
  CACCCCAAGCAAGAACTGGCTGTGGTGTGGGACAAACCAGATGGGTCACCGGACACCCCC
  ACCAAGGCTCCTGCCCTTNTCCCCTTCTGGAAGGCCCTCGAAGTTTCGCCTCACCTCAAA
  GCCCGGAGAAGGGCTGGAGCCTCCCCCCAACCTCACCCCCTGTGGCCCCTAGCCTGCACT
  ACGCGTGTCCTAACATAAAAACCCTTTCCNTGGCCCCTCCCCTTCCTGGTTCGGACCACC
  CCAAACATAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_021158
• ORF Size: 1077 bp
• Insert Size: 2210
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_021158.3, NP_066981.2
• RefSeq Size: 2469
• RefSeq ORF: 1077
• Locus ID: 57761
• Domains: pkinase, S_TKc
• Protein Families: Druggable Genome, Protein Kinase, Transcription Factors
• Gene Summary: The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (1, also known as 1A) represents the longest transcript and encode the predominant isoform (1).