MCCC1 (NM_020166) Human Untagged Clone

CAT#: SC113201

MCCC1 (untagged)-Human methylcrotonoyl-CoA carboxylase 1 (alpha) (MCCC1), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MCCC1
• Synonyms: MCC-B; MCCA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113201 sequence for NM_020166 edited (data generated by NextGen Sequencing)
  ATGGCGGCGGCCTCTGCGGTGTCGGTGCTGCTGGTGGCGGCGGAGAGGAACCGGTGGCAT
  CGTCTCCCGAGCCTGCTCCTGCCGCCGAGGACATGGGTGTGGAGGCAAAGAACCATGAAG
  TACACAACAGCCACAGGAAGAAACATTACCAAGGTCCTCATTGCAAACAGAGGAGAAATT
  GCCTGCAGGGTGATGCGCACAGCCAAAAAACTGGGTGTACAGACTGTGGCGGTTTATAGT
  GAGGCTGACAGAAATTCCATGCATGTAGATATGGCAGATGAAGCATATTCCATCGGCCCC
  GCTCCCTCCCAGCAGAGCTACCTATCTATGGAGAAAATCATTCAAGTGGCCAAGACCTCT
  GCTGCACAGGCTATCCATCCAGGATGCGGTTTTCTTTCAGAAAACATGGAATTTGCTGAA
  CTTTGTAAGCAAGAAGGAATTATTTTTATAGGCCCTCCTCCATCTGCAATTAGAGACATG
  GGTATAAAGAGCACATCCAAATCCATAATGGCTGCTGCTGGAGTACCTGTTGTGGAGGGT
  TATCATGGTGAGGACCAATCAGACCAGTGCCTGAAGGAACACGCCAGGAGAATTGGCTAT
  CCTGTCATGATTAAAGCCGTCCGGGGTGGAGGAGGAAAAGGAATGAGGATTGTTAGATCA
  GAACAAGAATTTCAAGAACAGTTAGAGTCAGCACGGAGAGAAGCTAAGAAGTCTTTCAAT
  GATGATGCTATGCTGATCGAGAAGTTTGTAGACACACCGAGGCATGTAGAAGTCCAGGTG
  TTTGGTGATCACCATGGCAATGCTGTGTACTTGTTTGAAAGAGACTGTAGTGTGCAGAGG
  CGACATCAGAAGATCATTGAGGAGGCCCCAGCGCCTGGTATTAAATCTGAAGTAAGAAAA
  AAGCTGGGAGAAGCTGCAGTCAGAGCTGCTAAAGCTGTAAATTATGTTGGAGCAGGGACT
  GTGGAGTTTATTATGGACTCAAAACATAATTTCTGTTTCATGGAGATGAATACAAGGCTG
  CAAGTGGAACATCCTGTTACTGAGATGATCACAGGAACTGACTTGGTGGAGTGGCAGCTT
  AGAATTGCAGCAGGAGAGAAGATTCCTTTGAGCCAGGAAGAAATAACTCTGCAGGGCCAT
  GCCTTCGAAGCTAGAATATATGCAGAAGATCCTAGCAATAACTTCATGCCTGTGGCAGGC
  CCATTAGTGCACCTCTCTACTCCTCGAGCAGACCCTTCCACCAGGATTGAAACTGGAGTA
  CGGCAAGGAGACGAAGTTTCCGTGCATTATGACCCCATGATTGCGAAGCTGGTCGTGTGG
  GCAGCAGATCGCCAGGCGGCATTGACAAAACTGAGGTACAGCCTTCGTCAGTACAATATT
  GTTGGACTGCCCACCAACATTGACTTCTTACTCAACCTGTCTGGCCACCCAGAGTTTGAA
  GCTGGGAACGTGCACACTGATTTCATCCCTCAACACCACAAACAGTTGTTGCTCAGTCGG
  AAGGCTGCAGCCAAAGAGTCTTTATGCCAGGCAGCCCTGGGTCTCATCCTCAAGGAGAAA
  GCCATGACCGACACTTTCACTCTTCAGGCACATGATCAATTCTCTCCATTTTCGTCTAGC
  AGTGGAAGAAGACTGAATATCTCGTATACCAGAAACATGACTCTTAAAGATGGTAAAAAC
  AATGTAGCCATAGCTGTAACGTATAACCATGATGGGTCTTATAGCATGCAGATTGAAGAT
  AAAACTTTCCAAGTCCTTGGTAATCTTTACAGCGAGGGAGACTGCACTTACCTGAAATGT
  TCTGTTAATGGAGTTGCTAGTAAAGCGAAGCTGATTATCCTGGAAAACACTATTTACCTA
  TTTTCCAAGGAAGGAAGTATTGAGATTGACATTCCAGTCCCCAAATACTTATCTTCTGTG
  AGCTCACAAGAAACTCAGGGCGGCCCCTTAGCTCCTATGACTGGAACCATTGAAAAGGTG
  TTTGTCAAAGCTGGAGACAAAGTGAAAGCGGGAGATTCCCTCATGGTTATGATCGCCATG
  AAGATGGAGCATACCATAAAGTCTCCAAAGGATGGCACAGTAAAGAAAGTGTTCTACAGA
  GAAGGTGCTCAGGCCAACAGACACACTCCTTTAGTCGAGTTTGAGGAGGAAGAATCAGAC
  AAAAGGGAATCGGAATAA
  
  Clone variation with respect to NM_020166.3
  396 c=>t;1391 a=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020166 unedited
  GGTTGTTCAGNNATATTTGTNAATACGCACTTCACTATAGNNGGCGGCCGCGCAATTCGG
  CACGAGGGCCCGCGGGGGTCACGAGGCTTCGTAGTGGAGGAACGGGTTTGGCGTGTGGGA
  CGCAGCTGCCTCTGTACTGGGGAGTCACGGAGTGGCCGGGCTCCAGGGACATGGCGGCGG
  CCTCTGCGGTGTCGGTGCTGCTGGTGGCGGCGGAGAGGAACCGGTGGCATCGTCTCCCGA
  GCCTGCTCCTGCCGCCGAGGACATGGGTGTGGAGGCAAAGAACCATGAAGTACACAACAG
  CCACAGGAAGAAACATTACCAAGGTCCTCATTGCAAACAGAGGAGAAATTGCCTGCAGGG
  TGATGCGCACAGCCAAAAAACTGGGTGTACAGACTGTGGCGGTTTATAGTGAGGCTGACA
  GAAATTCCATGCATGTAGATATGGCAGATGAAGCATATTCCATCGGCCCCGCTCCCTCCC
  AGCAGAGCTACCTATCTATGGAGAAAATCATTCAAGTGGCCAAGACCTCTGCTGCACAGG
  CTATCCATCCAGGATGCGGTTTTCTTTCAGAAAACATGGAATTTGCTGAACTTTGTAAGC
  AAGAAGGAATTATTTTTATAGGCCCTCCTCCATCTGCAATTAGAGACATGGGTATAAAGA
  GCACATCCAAATCCATAATGGCTGCTGCTGGAGTACCTGTTGTGGCACGGTTATCATGGT
  GAGGACCAATCAGACCAGTGCCTGGAGGAACACGCCAGNAGAATTGGCTATCCTGTCATG
  ATTAAAGCCGCCCGGGCTGGGAGGAAGGAAAATGATTGGACGCATTGGTTCCACCCCGAA
  ACAAGAATTTCTCAGAACCCGTTCACAGCCACGCACGGAAAGGAGCTTCAAAAACCTCTT
  TCAACGGATGACGCCTATGCCTGATTCGAAAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020166 unedited
  GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTCCCAAAAAAAAAAATTCACTTTTTTTATTTT
  AAAATTTTTGGAAAAAATTAGGGCCCCAAAGGCTTGATTTTCCAATTTAAAGGGGGTTCA
  CCTTAACCTTCCAATTTTTTAAAAAAACTGTTTTTTATAAAACCCCCAAAAAAGCGGGGG
  GCCTTTCTTTTTTTTGGGGGAAAAAAAAAACCTTTTTTAACGGGCCTTTTCTTTGGGGGA
  GTTAATCCCAATCCCCTTTGGGCGGATTTTTCCTCCCAAAACTCAATTAAAGGAGGGTGT
  TTTTTGGCCTAACCCCCTTTTTTGAAAAACATTTTTTTTACTGGGCCTTCTTTTGAAAAC
  TTTAGGGGAGCCCCCATTTTCGGGGGGATCTTAACCTTGGGGGAATCTCCCGTTTTCATT
  TTGTCCCCAGTTTTAAAAAACACCTTTTAAAGGGTTCCAACCATAGAACCTAAGGGGCCC
  CCCTGATTTTTTTGGGACCCCACAAAAAATAATTTTTGGGGGACGGGAATGCCAATCCCA
  ATACTTCCTTCCTTGAAAAAAGGAAAATAGGGTTTCCCAGAAAAAATCACTTTCTTTTTA
  CTACCAACTCCTTTAAAAAAACATTTAGGGTAAGGGCAGCCCCCCTCGCTGAAAAAATAC
  CAAGGCCTTGGAAAGTTTTATCTCAATTTGCTTGCTATAAAACCCCCAGGGTTATCCCTA
  CACCTATGGCTACTTGTTTTCCACATTTTTAAAAAACATGTTTCGGAGTAACAAGATATT
  AATTTTTTTTCACTGTGTAACAAAATGGGAAAATTTTCTTTTGTCCCGAAAAAGGAAAGT
  TCCGCCTTGGTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020166
• ORF Size: 2178 bp
• Insert Size: 2620
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020166.2, NP_064551.2
• RefSeq Size: 2528
• RefSeq ORF: 2178
• Locus ID: 56922
• Domains: biotin_lipoyl, CPSase_L_D2, CPSase_L_chain, Biotin_carb_C
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Valine, leucine and isoleucine degradation
• Gene Summary: This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1).