SLCO1B3 (NM_019844) Human Untagged Clone

CAT#: SC113235

SLCO1B3 (untagged)-Human solute carrier organic anion transporter family, member 1B3 (SLCO1B3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLCO1B3
• Synonyms: HBLRR; LST-2; LST-3TM13; LST3; OATP-8; OATP1B3; OATP8; SLC21A8
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_019844, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACCAACATCAACATTTGAATAAAACAGCAGAGTCAGCATCTTCAGAGAAAAAGAAAACAAGACGCT
  GCAATGGATTCAAGATGTTCTTGGCAGCCCTGTCATTCAGCTATATTGCTAAAGCACTAGGTGGAATCAT
  TATGAAAATTTCCATCACTCAAATAGAAAGGAGATTTGACATATCCTCTTCTCTTGCTGGTTTAATTGAT
  GGAAGCTTTGAAATTGGAAATTTGCTTGTGATTGTATTTGTAAGTTACTTTGGATCTAAACTACACAGAC
  CGAAGTTAATTGGAATTGGTTGTCTCCTTATGGGAACTGGAAGTATTTTGACATCTTTACCACATTTCTT
  CATGGGATATTATAGGTATTCTAAAGAAACCCATATTAATCCATCAGAAAATTCAACATCAAGTTTATCA
  ACCTGTTTAATTAATCAAACCTTATCATTCAATGGAACATCACCTGAGATAGTAGAAAAAGATTGTGTAA
  AGGAATCTGGGTCACACATGTGGATCTATGTCTTCATGGGGAATATGCTTCGTGGCATAGGGGAAACCCC
  CATAGTACCATTGGGGATTTCATACATTGATGATTTTGCAAAAGAAGGACATTCTTCCTTGTATTTAGGT
  AGTTTGAATGCAATAGGAATGATTGGTCCAGTCATTGGCTTTGCACTGGGATCTCTGTTTGCTAAAATGT
  ACGTGGATATTGGATATGTAGATCTGAGCACTATCAGAATAACTCCTAAGGACTCTCGTTGGGTTGGAGC
  TTGGTGGCTTGGTTTCCTTGTGTCTGGACTATTTTCCATTATTTCTTCCATACCATTTTTTTTCTTGCCG
  AAAAATCCAAATAAACCACAAAAAGAAAGAAAAATTTCACTATCATTGCATGTGCTGAAAACAAATGATG
  ATAGAAATCAAACAGCTAATTTGACCAACCAAGGAAAAAATGTTACCAAAAATGTGACTGGTTTTTTCCA
  GTCTTTGAAAAGCATCCTTACCAATCCCCTGTATGTTATATTTCTGCTTTTGACATTGTTACAAGTAAGC
  AGCTTTATTGGTTCTTTTACTTACGTCTTTAAATATATGGAGCAACAGTACGGTCAGTCTGCATCTCATG
  CTAACTTTTTGTTGGGAATCATAACCATTCCTACGGTTGCAACTGGAATGTTTTTAGGAGGATTTATCAT
  TAAAAAATTCAAATTGTCTTTAGTTGGAATTGCCAAATTTTCATTTCTTACTTCGATGATATCCTTCTTG
  TTTCAACTTCTATATTTCCCTCTAATCTGCGAAAGCAAATCAGTTGCCGGCCTAACCTTGACCTATGATG
  GAAATAATTCAGTGGCATCTCATGTAGATGTACCACTTTCTTATTGCAACTCAGAGTGCAATTGTGATGA
  AAGTCAGTGGGAACCAGTCTGTGGGAACAATGGAATAACTTACCTGTCACCTTGTCTAGCAGGATGCAAA
  TCCTCAAGTGGTATTAAAAAGCATACAGTGTTTTATAACTGTAGTTGTGTGGAAGTAACTGGTCTCCAGA
  ACAGAAATTACTCAGCACACTTGGGTGAATGCCCAAGAGATAATACTTGTACAAGGAAATTTTTCATCTA
  TGTTGCAATTCAAGTCATAAACTCTTTGTTCTCTGCAACAGGAGGTACCACATTTATCTTGTTGACTGTG
  AAGATTGTTCAACCTGAATTGAAAGCACTTGCAATGGGTTTCCAGTCAATGGTTATAAGAACACTAGGAG
  GAATTCTAGCTCCAATATATTTTGGGGCTCTGATTGATAAAACATGTATGAAGTGGTCCACCAACAGCTG
  TGGAGCACAAGGAGCTTGTAGGATATATAATTCCGTATTTTTTGGAAGGGTCTACTTGGGCTTATCTATA
  GCTTTAAGATTCCCAGCACTTGTTTTATATATTGTTTTCATTTTTGCTATGAAGAAAAAATTTCAAGGAA
  AAGATACCAAGGCATCGGACAATGAAAGAAAAGTAATGGATGAAGCAAACTTAGAATTCTTAAATAATGG
  TGAACATTTTGTACCTTCTGCTGGAACAGATAGTAAAACATGTAATTTGGACATGCAAGACAATGCTGCT
  GCCAACTAA
  
  
• Restriction Sites: NotI-NotI
• ACCN: NM_019844
• ORF Size: 2109 bp
• Insert Size: 3000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_019844.1, NP_062818.1
• RefSeq Size: 2646
• RefSeq ORF: 2109
• Locus ID: 28234
• Domains: OATP_N, OATP_C
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
  Transcript Variant: This variant (1) encodes the longer isoform (1), which is highly expressed in the liver. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.