UBE2W (NM_018299) Human Untagged Clone

CAT#: SC113604

UBE2W (untagged)-Human ubiquitin-conjugating enzyme E2W (putative) (UBE2W), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBE2W
• Synonyms: UBC-16; UBC16
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_018299, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTGAGCCCCCGCGGCGTGACGCGAGCACGGCAGCTCCTCCCCCTGCGTCTCTGGCCTCGCCGGTCTT
  GGGGGGATGGTTCCATCATGGCGTCAATGCAGAAACGACTACAGAAAGAACTGTTGGCTTTGCAAAATGA
  CCCACCTCCTGGAATGACCTTAAATGAGAAGAGTGTTCAAAATTCAATTACACAGTGGATTGTAGACATG
  GAAGGTGCACCAGGTACCTTATATGAAGGGGAAAAATTTCAACTTCTATTTAAATTTAGTAGTCGATATC
  CTTTTGACTCTCCTCAGGTCATGTTTACTGGTGAAAATATTCCTGTTCATCCTCATGTTTATAGCAATGG
  TCATATCTGTTTATCCATTCTAACAGAAGACTGGTCCCCAGCGCTCTCAGTCCAATCAGTTTGTCTTAGC
  ATTATTAGCATGCTTTCCAGCTGCAAGGAAAAGAGACGACCACCGGATAATTCTTTTTATGTGCGAACAT
  GTAACAAGAATCCAAAGAAAACAAAATGGTGGTATCATGATGATACTTGTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018299 unedited
  ATAGGCCGGCCGCGAATTCGCACGAGGCTCTGGCCTCGCCGGTCTTGGGGGGATGGTTCC
  ATCATGGCGTCAATGCAGAAACGACTACAGAAAGAACTGTTGGCTTTGCAAAATGACCCA
  CCTCCTGGAATGACCTTAAATGAGAAGAGTGTTCAAAATTCAATTACACAGTGGATTGTA
  GACATGGAAGGTGCACCAGGTACCTTATATGAAGGGGAAAAATTTCAACTTCTATTTAAA
  TTTAGTAGTCGATATCCTTTTGACTCTCCTCAGGTCATGTTTACTGGTGAAAATATTCCT
  GTTCATCCTCATGTTTATAGCAATGGTCATATCTGTTTATCCATTCTAACAGAAGACTGG
  TCCCCAGCGCTCTCAGTCCAATCAGTTTGTCTTAGCATTATTAGCATGCTTTCCAGCTGC
  AAGGAAAAGAGACGACCACCGGATAATTCTTTTTATGTGCGAACATGTAACAAGAATCCA
  AAGAAAACAAAATGGTGGTATCATGATGATACTTGTTGATGCCACTGTTATCATCCTCCT
  AGCAAAGATAGTCCTACTGAGAAAATGAGCACTTTGATCATTCAGTCTTTGAACTTTTAC
  CTTTGCTGGNAAGTGACCTATAGGCAATGAAGACTACTNTCTTTTACTGCATTTTTACCT
  CGTGTGCATTCTGGGCGCTTGTTGATCCCTGGGGTTCAATCCAGGCAACTGACATGCTTT
  NATTAGTCATACAGTATATGGGGCAGGTGTAGGAAATGTCAATATAATTCCATTNTTTAT
  TTTTTATTTTTTTTAAGCTTTTGAAAGCCTCCAGTCCCTCCTGGGTATGTGCATAACATA
  CTTCTTTGTGGGGGGGGGNTGTGGGGCCCTCTATGCGCAGGGGGGGGGTTGACAAAAAAA
  AAAGAGTTATTTTACTCTGCCTTCATGATATGCCCGAAAAGGCCATGAATACATACTGTT
  TTTTGGGGGAGATAAATAAAAGGGGGGGGGGCCCCCTTTTTTTAATTCCCCCCCGCTTTT
  TTTTGATTTTCCCCGGGGCCCCCCCGGGGACACGATAACAACCCTTTTTGGAGGGGGGGA
  GAAAATATA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018299 unedited
  TATGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTAGGGACACTGAATTCTTTATTTAAAAAAATTTTTGGAACACACAGTACCTC
  CTCTTCTCTTCTATTTTTAGGAAAAAGTTATAACAAGTTTTAAATATCTCAATTCTGAAA
  AACAATAGGCTTCTTAAAAAATAAGACTTGATTACCAGAAACAAGTAATATGGAGTTACA
  TAACCATTTTCATATCACTACTCATTTCCATTATTTACCAATTCATCTTTGATGCAACTT
  GGAAACAATTAAGCAGTCACTAAACACCTGTTTTAAAATCTGAAGAAATTATTATCCACC
  ACAGGAATCTAATGATATATATATTTGCATATATTTAAAATTTCATGAGGGAAAAGGGAA
  TAAACTATTCTAGTTATTTTATACCAAATATTGATATTCCTAGCCAAAACAACAAGGAAT
  TAAGATCTTTCTCCAGGGGAACTGCTGACTATATAAAAGCTATTTCCAGCACTTTCTTCT
  GGGGATTAAAAATGATTTATTTCCCTGCTGGCTAAAATGATAAATTATATATTACAAGTA
  AGCCCTTCAGAAGGGAATATTAATTCCTTAAGAGAACCATAAAATGTATTTTTAAAAAAT
  TCTCTTAAAAACTGAAAACAATCCTTCTCTCTAAACCTATGGCATTAATCCCTACTTGAC
  CAAAGAAAAAAAAAAAAAAGAAGGGCATCATGTTCATGATCTAAGCATGCCTAAATAAGG
  AAGCAAATGTATCACTGCCTTAATAGATTTGGNCAACCAGAAGATGGCCTANNAATANNT
  AATAATTAATAAAGAAGAAGGGCGGTCCTTATCTTCTAGNATGAAAGTCTAATCTGTAGG
  CCTATGTCGCAATATGGCCCACGAGAATGCNGGAGGNAGCAGNANCAATTCCTATTACAT
  TCTGAAATCCGGGGGGCTTCACAAGCTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018299
• ORF Size: 456 bp
• Insert Size: 3780
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_018299.2, NP_060769.2
• RefSeq Size: 4024
• RefSeq ORF: 456
• Locus ID: 55284
• Domains: UBCc
• Protein Families: Transcription Factors
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. CCDS Note: The coding region has been updated to shorten the N-terminus to one that is more supported by conservation.