SCYL2 (NM_017988) Human Untagged Clone

CAT#: SC113782

SCYL2 (untagged)-Human SCY1-like 2 (S. cerevisiae) (SCYL2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SCYL2
• Synonyms: CVAK104
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113782 sequence for NM_017988 edited (data generated by NextGen Sequencing)
  ATGGAGTCCATGCTTAATAAATTGAAGAGTACTGTTACAAAAGTAACAGCTGATGTCACT
  AGTGCTGTAATGGGAAATCCTGTCACTAGAGAATTTGATGTTGGTCGACACATTGCCAGT
  GGTGGCAATGGGCTAGCTTGGAAGATTTTTAATGGCACAAAAAAGTCAACAAAGCAGGAA
  GTGGCAGTTTTTGTCTTTGATAAAAAACTGATTGACAAGTATCAAAAATTTGAAAAGGAT
  CAAATCATTGATTCTCTAAAACGAGGAGTCCAACAGTTAACTCGGCTTCGACACCCTCGA
  CTTCTTACTGTCCAGCATCCTTTAGAAGAATCCAGGGATTGCTTGGCATTTTGTACAGAA
  CCAGTTTTTGCCAGTTTAGCCAATGTTCTTGGTAACTGGGAAAATCTACCTTCCCCTATA
  TCTCCAGACATTAAGGATTATAAACTTTATGATGTAGAAACCAAATATGGTTTGCTTCAG
  GTTTCTGAAGGATTGTCATTCTTGCATAGCAGTGTGAAAATGGTGCATGGAAATATCACT
  CCTGAAAATATAATTTTGAATAAAAGTGGAGCCTGGAAAATAATGGGTTTTGATTTTTGT
  GTATCATCAACCAATCCTTCTGAACAAGAGCCTAAATTTCCTTGTAAAGAATGGGACCCA
  AATTTACCTTCATTGTGTCTTCCAAATCCTGAATATTTGGCTCCTGAATACATACTTTCT
  GTGAGCTGTGAAACAGCCAGTGATATGTATTCTTTAGGAACTGTTATGTATGCTGTATTT
  AATAAAGGGAAACCTATATTTGAAGTCAACAAGCAAGATATTTACAAGAGTTTCAGTAGG
  CAGTTGGATCAGTTGAGTCGTTTAGGATCTAGTTCACTTACAAATATACCTGAGGAAGTT
  CGTGAACATGTAAAGCTACTGTTAAATGTAACTCCGACTGTAAGACCAGATGCAGATCAA
  ATGACAAAGATTCCCTTCTTTGATGATGTTGGTGCAGTAACACTGCAATATTTTGATACC
  TTATTCCAAAGAGATAATCTTCAGAAATCACAGTTTTTCAAAGGACTGCCAAAGGTTCTA
  CCAAAACTGCCCAAGCGTGTCATTGTGCAGAGAATTTTGCCTTGTTTGACTTCAGAATTT
  GTAAACCCTGACATGGTACCTTTTGTTTTGCCCAATGTTYTACTTATTGCTGAGGAATGC
  ACCAAAGAAGAATATGTCAAATTAATTCTTCCTGAACTTGGCCCTGTGTTTAAGCAGCAG
  GAGCCAATCCAGATTTTGTTAATTTTCCTACAAAAAATGGATTTGCTACTAACCAAAACC
  CCTCCTGATGAGATAAAGAACAGTGTTCTACCCATGGTTTACAGAGCACTAGAAGCTCCT
  TCCATTCAGATCCAGGAGCTCTGTCTAAACATCATTCCAACCTTTGCAAATCTTATAGAC
  TACCCATCCATGAAAAACGCTTTGATACCAAGAATTAAAAATGCTTGTCTACAAACATCT
  TCCCTTGCGGTTCGTGTAAATTCATTAGTGTGCTTAGGAAAGATTTTGGAATACTTGGAT
  AAGTGGTTTGTACTTGATGATATCCTACCCTTCTTACAACAAATTCCATCCAAGGAACCT
  GCGGTCCTCATGGGAATTTTAGGTATTTACAAATGTACTTTTACTCATAAGAAGTTGGGA
  ATCACCAAAGAGCAGCTGGCCGGAAAAGTGTTGCCTCATCTTATTCCCCTGAGTATTGAA
  AACAATCTTAATCTTAATCAGTTCAATTCTTTCATTTCCGTCATAAAAGAAATGCTTAAT
  AGATTGGAGTCTGAACATAAGACTAAACTGGAGCAACTTCATATAATGCAAGAACAGCAG
  AAATCTTTGGATATAGGAAATCAAATGAATGTTTCTGAGGAGATGAAAGTTACAAATATT
  GGGAATCAGCAAATTGACAAAGTTTTTAACAACATTGGAGCAGACCTTCTGACTGGCAGT
  GAGTCCGAAAATAAAGAGGACGGGTTACAGAATAAACATAAAAGAGCATCACTTACACTT
  GAAGAAAAACAAAAATTAGCAAAAGAACAAGAGCAGGCACAGAAGCTGAAAAGCCAGCAG
  CCTCTTAAACCCCAAGTGCACACACCTGTTGCTACTGTTAAACAGACTAAGGACTTGACA
  GACACACTGATGGATAATATGTCATCCTTGACCAGCCTTTCTGTTAGTACCCCTAAATCT
  TCTGCTTCAAGTACTTTCACTTCTGTTCCTTCCATGGGCATTGGTATGATGTTTTCTACA
  CCAACTGATAATACAAAGAGAAATTTGACAAATGGCCTAAATGCCAATATGGGCTTTCAG
  ACTTCAGGATTCAACATGCCCGTTAATACAAACCAGAACTTCTACAGTAGTCCAAGCACA
  GTTGGAGTGACCAAGATGACTCTGGGAACACCTCCCACTTTGCCAAACTTCAATGCTTTG
  AGTGTTCCTCCTGCTGGTGCAAAGCAGACCCAACAAAGACCCACAGATATGTCTGCCCTT
  AATAATCTCTTTGGCCCTCAGAAACCCAAAGTTAGCATGAACCAGTTATCACAACAGAAA
  CCAAATCAGTGGCTTAATCAGTTTGTACCTCCTCAAGGTTCTCCAACTATGGGCAGTTCA
  GTAATGGGGACACAGATGAACGTGATAGGACAATCTGCTTTTGGTATGCAGGGTAATCCT
  TTCTTTAACCCACAGAACTTTGCACAGCCACCAACTACTATGACCAATAGCAGTTCAGCT
  AGCAATGATTTAAAAGATCTTTTTGGGTGA
  
  Clone variation with respect to NM_017988.4
  1180 c=>y
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017988 unedited
  CTATAGGGGCGGCCGCGATTCGGCACGAGGCCCCTCCCCACCCCTTTCCTTCTAGCTCCG
  ACGTTTGCGGCCGCGGGGGCGGCGGAGGATATGGAGTAAAGCCAGAGTCAGTGGCCAGGC
  ACGAAGGCAGAGCAGGAACAGCCAGGAGGCGTTTATTAGGGGGGCGGGGGGAAAGAGCCC
  CAGCACCGCCCCTCCTGGAAGAAGGAAGAGGTAACTATAACTACCCAATATTGCAGCCAT
  GGAGTCCATGCTTAATAAATTGAAGAGTACTGTTACAAAAGTAACAGCTGATGTCACTAG
  TGCTGTAATGGGAAATCCTGTCACTAGAGAATTTGATGTTGGTCGACACATTGCCAGTGG
  TGGCAATGGGCTAGCTTGGAAGATTTTTAATGGCACAAAAAAGTCAACAAAGCAGGAAGT
  GGCAGTTTTTGTCTTTGATAAAAAACTGATTGACAAGTATCAAAAATTTGAAAAGGATCA
  AATCATTGATTCTCTAAAACGAGGAGTCCAACAGTTAACTCGGCTTCGACACCCTCGACT
  TCTTACTGTCCAGCATCCTTTAGAAGAATCCAGGGATTGCTTGGCATTNTGTACAGAACC
  AGTTTTTGCCAGTTTAGCCAATGTTCTTGGTAACTGGGAAAATCTACCTTCCCCTATATC
  TCCAGACATTAAGGATTATAAACTTTATGATGTAGAAACCAAATATGGGTTGCTTCAGGT
  TTCTGAAGGATTGTCATTCTTGCATAGCAGTGTGAAAATGGTGCATGGAAATATCACTCC
  TGAAAATATATTTTGAATANAGTGGAGCCTGAANATAATGGGGTTTTGATTTTGTGTATC
  ATCACCAATCCTTCTGACAGAGCCTAAATTCCTTGTAAGAATGGACCAAATTACCTTCAT
  GGGTCTCCAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017988 unedited
  TCCTCTGCCGCACTCNANAGTTGAGTTTATTTCTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTGAAAGGTTACTCCTAAATATAGTTTAATTCTTACAAATCTTC
  TTTTGAAAAGGCAATTCATATTTGCTGCACCCCCAAAAGTTTGAATTTGAAATGAAATAT
  GAAGGGAGTAGTCAGGGAAGTCACATCATTTTGCCTTGGCAAATTTCCAAACAAATGGGG
  CCATCCCTTTTCCTTGTTACGGGGGGAAAAAAGGGTTTTTAAATTTTTCCAAGGGAATGC
  CAAAAAATCCTTTTCTTTTTGGGGCCAACCCTGCTAAAATATAATTTACAAGGATTAGTT
  TGCCCTTAAAAGGGTTAAAAACCCTTTTAACCCCATGAAATGAAGGTTAAGTTGAATTTT
  GGAGTATTTGCTCAGTCTTTGGCCTAAACAATAGTTCATTTGAAAAGTTTGGAAAAAGCA
  AATAACCGGGAACTTCTCTTTATGCTTATAATTTTCCCACGGGCATCTTAAAGGCCAACA
  AATCAATCCCGCTTCAAGATTTTTTCCCTTTTAAAATGAAGACTAATGCCTCTTAGACTG
  GGTCCCATATAGTACTTAAAAGATGAGCTTGGAAGGACCCTCCCCTCATTTTTTAAATAC
  CCCGAGTTCCCCAGGCAAAAAAAACTTTGGTTTAAAAGTTTTGTTATTCAGAAACCCCGG
  TTCCTTTTTCTTTTGAAATGGGAAGGGCTGGTCTTAAAAACCGAAAGAGTTGGAAGAGAA
  AAAACCTCAGCTTAAAAACTCCCTGGTAAAGTCTACACTCTTGCTGCCTGGCAAAAGTTT
  CTGGCCAAATGTACTTTCCATAAAATCTCCCCCGCCCCTTTTAGAAGGAAACCCCCCCCT
  GTTGAACCGAAAACCTTCAAAAAAGAAACCTTCCCCAAATTTTAATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017988
• ORF Size: 2790 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017988.4, NP_060458.3
• RefSeq Size: 3818
• RefSeq ORF: 2790
• Locus ID: 55681
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]
  Transcript Variant: This variant (1) encodes isoform 1. Both variants 1 and 2 encode the same protein.