SARS2 (NM_017827) Human Untagged Clone

CAT#: SC113914

SARS2 (untagged)-Human seryl-tRNA synthetase 2, mitochondrial (SARS2), nuclear gene encoding mitochondrial protein, transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SARS2
• Synonyms: mtSerRS; SARS; SARSM; SerRS; SerRSmt; SERS; SYS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017827, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTGCGTCCATGGCGCGGCGCTTGTGGCCTTTGCTGACTCGTCGGGGGTTCCGGCCCCGGGGAGGCT
  GCATCTCCAACGATAGTCCAAGGAGAAGTTTCACTACAGAGAAACGAAACCGGAACCTCCTGTACGAGTA
  TGCGCGCGAGGGCTACAGCGCACTCCCTCAGCTGGACATAGAGCGGTTCTGCGCATGCCCAGAAGAGGCC
  GCACACGCCCTGGAGCTCCGCAAGGGGGAGCTGCGCTCGGCGGACCTGCCCGCGATCATCTCGACATGGC
  AGGAGCTGAGGCAGCTGCAGGAGCAGATCCGGAGCCTGGAGGAAGAGAAGGCAGCTGTGACTGAGGCAGT
  GCGGGCCCTGCTGGCAAACCAGGACAGTGGTGAAGTGCAGCAGGACCCCAAGTACCAGGGTCTGCGGGCA
  CGTGGCCGGGAGATCCGGAAGGAGCTTGTTCACCTGTACCCCAGGGAGGCCCAGCTTGAGGAGCAGTTCT
  ACCTGCAGGCGCTGAAGCTGCCCAACCAGACCCACCCAGACGTGCCCGTCGGGGATGAGAGCCAGGCTCG
  AGTGCTCCACATGGTCGGAGACAAGCCAGTTTTCTCCTTCCAACCTCGGGGCCACCTGGAAATTGGCGAG
  AAACTCGACATCATCCGTCAGAAGCGCCTGTCCCACGTGTCTGGCCACCGGTCCTATTACCTGCGCGGGG
  CTGGAGCCCTCCTGCAGCACGGCCTGGTCAACTTCACATTCAACAAGCTTCTCCGCCGGGGCTTCACCCC
  CATGACGGTGCCAGACCTTCTCCGCGGAGCAGTGTTTGAAGGCTGTGGGATGACACCAAATGCCAACCCA
  TCCCAAATTTACAACATCGACCCTGCCCGCTTCAAAGATCTCAACCTGGCTGGAACAGCGGAGGTGGGGC
  TTGCAGGCTACTTCATGGACCACACCGTGGCCTTCAGGGACCTGCCAGTCAGGATGGTTTGCTCCAGCAC
  CTGCTACCGGGCAGAGACAAACACGGGACAGGAACCCCGGGGGCTGTATCGAGTACACCACTTCACCAAG
  GTGGAGATGTTTGGGGTGACAGGCCCTGGGCTGGAGCAGAGCTCACAGCTGCTGGAGGAGTTCCTGTCCC
  TTCAGATGGAGATCTTGACAGAGCTGGGCTTGCACTTCCGGGTCCTGGATATGCCCACCCAAGAACTGGG
  CCTCCCCGCCTACCGCAAGTTTGACATTGAGGCCTGGATGCCAGGCCGAGGCCGCTTTGGAGAGGTCACC
  AGTGCTTCCAACTGCACAGACTTCCAGAGCCGCCGCCTCCACATCATGTTCCAGACCGAGGCTGGGGAGC
  TGCAGTTTGCCCACACGGTGAACGCCACCGCCTGTGCTGTCCCCCGCCTTCTCATCGCGCTCCTGGAGAG
  TAACCAGCAGAAGGACGGCTCAGTGCTCGTGCCCCCTGCCCTCCAGTCCTACCTCGGCACTGATCGGATC
  ACAGCCCCTACCCACGTGCCTCTCCAGTACATCGGCCCCAACCAGCCCCGGAAGCCTGGGCTGCCTGGCC
  AGCCTGCTGTAAGCTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017827 unedited
  TTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGTCCAAGATGGCTG
  CGTCCATGGCGCGGCGCTTGTGGCCTTTGCTGACTCGTCGGGGGTTCCGGCCCCGGGGAG
  GCTGCATCTCCAACGATAGTCCAAGGAGAAGTTTCACTACAGAGAAACGAAACCGGAACC
  TCCTGTACGAGTATGCGCGCGAGGGCTACAGCGCACTCCCTCAGCTGGACATAGAGCGGT
  TCTGCGCATGCCCAGAAGAGGCCGCACACGCCCTGGAGCTCCGCAAGGGGGAGCTGCGCT
  CGGCGGACCTGCCCGCGATCATCTCGACATGGCAGGAGCTGAGGCAGCTGCAGGAGCAGA
  TCCGGAGCCTGGAGGAAGAGAAGGCAGCTGTGACTGAGGCAGTGCGGGCCCTGCTGGCAA
  ACCAGGACAGTGGTGAAGTGCAGCAGGTACTGTGAAGAGTTGATGTCCTATCCAGGGTTG
  GGGGTGGGCAGGGAGGATACCCTGCCAGTCACGATTCTACTATTGTAACAGAAAAACAAC
  TCAAACAGGTTTAAGGGGAAAAAAAAATAGGCTCTATTGATGCATGAAACTATAACTGGC
  TTCAGGTGCGGCTGGATCCAGGTGCCTGCTCCATATTTGGTCCTACGTTCCTCCCATTCC
  CAGGCCAGTTTCTCCTCTTGTGTAAGGACGAGGCAAAGCCAAGCCCGCCTTTCTGATAGT
  CCAGTTAAGTCCTGGGCTGGATTTCATGATTCAACTGAATCAGGTGCCTGTCTCTGAACA
  GCCATTGCGGCCAGGGCATAAACGTTCTAGTTGGCCGGCCTGATTTTTTCCCACAAACTG
  CCTGGGGGGGAGGGAAATCTGGAAAAATTAGGATCCGGCCCTGAAAAAGCTCACGCCACC
  CGGGCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017827 unedited
  GCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGTCCTGACCATTTATTGGGGACT
  TTTTGCTCAGCACTGTAGGAGGAAAGAAGGAAGGAGGGATGGAAGCCTCTTCCTCTGCTT
  CTCCTGTCCCTAGAACCGTAAAGCCCAGACGTCCTGCTTCCCACTGGGACCCTCAATGAT
  AACAGGGTCAGTGACTGACTCTGAGGCAGCAAGGACAGAGGAGAGGTGGACCCCGTGGTC
  CAGGGGCCCGGGCGTGGAGCTGACAGGAAGAACACAGATGTCAGGACGGGCTCAGCAACA
  CAGGTCCCAGGTGTCCGGGGTCTCCTGAACTCCAGGAAGCAGTGACACCCCCGAGGGCTG
  CTGTGGGTGGGTTCTTAGCTTACAGCAGGCTGGCCAGGCAGCCCAGGCTTCCGGGGCTGG
  TTGGGGCCGATGTACTGGAGAGGCACGTGGGTAGGGGCTGTGATCCGATCAGTGCCGAGG
  TAGGACTGGAGGGCAGGGGGCACGAGCACTGAGCCGTCCTTCTGCTGGTTACTCTCCAGG
  AGCGCGATGAGAAGGCGGGGGACAGCACAGGCGGTGGCGTTCACCGTGTGGGCAAACTGC
  AGCTCCCCAGCCTCGGTCTGGAACATGATGTGGAGGCGGCCGCTCTGGAAGTCTGTGCAG
  TTGGAAGCACTGTGACCTCTCCAAAACGGGCTCGGGCTGGCATCCAGGCCTTAATGGAAA
  ACTTGCGGTAAGGGGNGAAGGCCCATTTCTTGGGTGGGCATATCCAGGACCCGGGAAGGG
  CAGCCCCCGCTCTGTACAGATCTCCATCTGAAGGACCAGGAACTCTCTCCACCAACTGGT
  GAACTCTGGTCCCAACCAAGGCCTGGTACCCCAAACATTTTCCCTCTGGTGAAATGGGGG
  TCCTCAAATAACCCCCCTGGGTGTCCTGCTCCCGTTTTGCCTTTGCCGCGAACAGGGCCG
  GAACAAACTATCTCGACGGACGGTCCCTGAAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017827
• ORF Size: 1557 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017827.2, NP_060297.1
• RefSeq Size: 2067
• RefSeq ORF: 1557
• Locus ID: 54938
• Domains: tRNA-synt_2b
• Protein Pathways: Aminoacyl-tRNA biosynthesis
• Gene Summary: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
  Transcript Variant: This variant (2) lacks an alternate exon and uses an alternate splice site in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform b which is 2 aa shorter than isoform a.