DUS2L (DUS2) (NM_017803) Human Untagged Clone

CAT#: SC113958

DUS2L (untagged)-Human dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae) (DUS2L)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DUS2
• Synonyms: DUS2L; SMM1; URLC8
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113958 sequence for NM_017803 edited (data generated by NextGen Sequencing)
  ATGATTTTGAATAGCCTCTCTCTGTGTTACCATAATAAGCTAATCCTGGCCCCAATGGTT
  CGGGTAGGGACTCTTCCAATGAGGCTGCTGGCCCTGGATTATGGAGCGGACATTGTTTAC
  TGTGAGGAGCTGATCGACCTCAAGATGATTCAGTGCAAGAGAGTTGTTAATGAGGTGCTC
  AGCACAGTGGACTTTGTCGCCCCTGATGATCGAGTTGTCTTCCGCACCTGTGAAAGAGAG
  CAGAACAGGGTGGTCTTCCAGATGGGGACTTCGGACGCAGAGCGAGCCCTTGCTGTGGCC
  AGGCTTGTAGAAAATGATGTGGCTGGTATTGATGTCAACATGGGCTGTCCAAAACAATAT
  TCCACCAAGGGAGGAATGGGAGCTGCCCTGCTGTCAGACCCTGACAAGATTGAGAAGATC
  CTCAGCACTCTTGTTAAAGGGACACGCAGACCTGTGACCTGCAAGATTCGCATCCTGCCA
  TCGCTAGAAGATACCCTGAGCCTTGTGAAGCGGATAGAGAGGACTGGCATTGCTGCCATC
  GCAGTTCATGGGAGGAAGCGGGAGGAGCGACCTCAGCATCCTGTCAGCTGTGAAGTCATC
  AAAGCCATTGCTGATACCCTCTCCATTCCTGTCATAGCCAACGGAGGATCTCATGACCAC
  ATCCAACAGTATTCGGACATAGAGGACTTTCGACAAGCCACGGCAGCCTCTTCCGTGATG
  GTGGCCCGAGCAGCCATGTGGAANNCATCTATCTTCCTCAAGGAGGGTCTGCGGCCCCTG
  GAGGAGGTCATGCAGAAATACATCAGATACGCGGTGCAGTATGACAACCACTACACCAAC
  ACCAAGTACTGCTTGTGCCAGATGCTACGAGAACAGCTGGAGTCGCCCCAGGGAAGGTTG
  CTCCATGCTGCCCAGTCTTCCCGGGAAATTTGTGAGGCCTTTGGCCTTGGTGCCTTCTAT
  GAGGAGACCACACAGGAGCTGGATGCCCAGCAGGCCAGGCTCTCAGCCAAGACTTCAGAG
  CAGACAGGGGAGCCAGCTGAAGATACCTCTGGTGTCATTAAGATGGCTGTCAAGTTTGAC
  CGGAGAGCATACCCAGCCCAGATCACCCCTAAGATGTGCCTACTAGAGTGGTGCCGGAGG
  GAGAAGTTGGCACAGCCTGTGTATGAAACGGTTCAACGCCCTCTAGATCGCCTGTTCTCC
  TCTATTGTCACCGTTGCTGAACAAAAGTATCAGTCTACCTTGTGGGACAAGTCCAAGAAA
  CTGGCGGAGCAGGCTGCAGCCATCGTCTGTCTGCGGAGCCAGGGCCTCCCTGAGGGTCGG
  CTGGGTGAGGAGAGCCCTTCCTTGCACAAGCGAAAGAGGGAGGCTCCTGACCAAGACCCT
  GGGGGCCCCAGAGCTCAGGAGCTAGCACAACCTGGGGATCTGTGCAAGAAGCCCTTTGTG
  GCCTTGGGAAGTGGTGAAGAAAGCCCCCTGGAAGGCTGGTGA
  
  Clone variation with respect to NM_017803.3
  273 a=>g;744 c=>n;745 c=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017803 unedited
  ACATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGGCACGAGGGTACGGTGTGTG
  GAGCTGGAGCACCGTGAGGAAGAAGCGAGGTTCTTTTTAAGAGTTCAGCTGCGAGATATC
  AAACAAAGAATTACTCTGTACAAAGCCAGAACACATATATCAAAGTAATCCTGAAGTATC
  AGAACAAAATAATAGGCTGTAACAGAGGAGGAAATGATTTTGAATAGCCTCTCTCTGTGT
  TACCATAATAAGCTAATCCTGGCCCCAATGGTTCGGGTAGGGACTCTTCCAATGAGGCTG
  CTGGCCCTGGATTATGGAGCGGACATTGTTTACTGTGAGGAGCTGATCGACCTCAAGATG
  ATTCAGTGCAAGAGAGTTGTTAATGAGGTGCTCAGCACAGTGGACTTTGTCGCCCCTGAT
  GATCGAGTTGTCTTCCGCACCTGTGAAAGAGAGCAGAACAGGGTGGTCTTCCAGATGGGG
  ACTTCGGACGCAGAGCGAGCCCTTGCTGTGGCCAGGCTTGTAGAAAATGATGTGGCTGGT
  ATTGATGTCAACATGGGCTGTCCAAAACAATATTCCACCAAGGGAGGAATGGGAGCTGCC
  CTGCTGTCAGACCCTGACAAGATTGAGAAGATCCTCAGCACTCTTGTTAAAGGGACACGC
  AGACCTGTGACCTGCAAGATTCGCATCCTGCCATCGCTAGAAGAACCCTGAGCCTTGTGA
  AGCGGATAGAGAGGACTGGCATTGCTGCCATCGCAGNTCATGGGAGGAAAGCGGAGGAGC
  GACCTCACCATCCTGTCAGCTGTGAAGTCATCAAAGCCATTGCTGATACCCTCTCCATTC
  CTGTCATAGCCAACGGAGGATCTCATGACCACATTCCACAGTATTCGGACATAGAGGACT
  TTCGACAGCCACGGCAGCCTCTTNCGTGATGGTGGCCCGAGCAGCCATGTTGAACCATCT
  ATCTTCTN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017803 unedited
  TCTATGAACCGCAGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTATGAAGATG
  CCCAAGGCTGAAGCAGCCAGCCGTGGGTGAGGGTAGGGGGTGTCTTTATTGCACAGTACC
  AATGTCAGGTTGGGGAGTTACCACCTGAAAAGCTCCTGTTTTCAAAGAGAACTTGACCCT
  GTCACTCAGATCCACCAAAGGGGCCAGGATCCACCCCTGGGCGGCCCCTGGTCCATGCTC
  TAGGCTGATGGCCCCTGCCAGGACATCTAACTTCTGCCAGGCAAGACCAGCAAACTGTTC
  AACGGCATCTGGTTCATGCTGTGGCATCCACAGCCACCTTAGCACCAGGCCCATGGAGGG
  GTGACTAAGGCAGGAAGAGTAGTCACCAGCCTTCCAGGGGGCTTTCTTCACCACTTCCCA
  AGGCCACAAAGGGCTTCTTGCACAGATCCCCAGGTTGTGCTAGCTCCTGAGCTCTGGGGC
  CCCCAGGGTCTTGGTCAGGAGCCTCCCTCTTTCGCTTGTGCAAGGAAGGGCTCTCCTCAC
  CCAGCCGACCCTCAGGGAGGCCCTGGCTCCGCAGACAGACGATGGCTGCAGCCTGCTCCG
  CCAGTTTCTTGGACTTGTCCCACAAGGTAGACTGATACTTTTGTTCAGCAACGGTGACAA
  TAGAGGAGAACAGGCGATCTAGAGGGCGTTGAACCGTTTCATACACAGGCTGTGCCAACT
  TCTCCCTCCGGCACCACTCTAGTAAGCACATCTTANGGGTGATCTGGGCTGGGTATGCTC
  TCCGGTCAAACTTGACAGCCATCTTAATGACACCAGAGGTATCTTCAGCTGGCTCCCCTG
  TCTGCTCTGAAATCTTGGCTGAAAGCCTTGGCTGCTGGGCATCCAGCTTCTGTGTGGGTC
  TCTCATAGAAGCACCAAGGCCAAAGCCCTACAATTTCCCGGNAAGACTGGCANCATGGAG
  CAACCTTCCTTGGGCGACTCCGCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017803
• ORF Size: 1482 bp
• Insert Size: 2190
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017803.3, NP_060273.1
• RefSeq Size: 1999
• RefSeq ORF: 1482
• Locus ID: 54920
• Domains: DSRM, Dus
• Gene Summary: This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).