Cytohesin 2 (CYTH2) (NM_017457) Human Untagged Clone

CAT#: SC114117

CYTH2 (untagged)-Human cytohesin 2 (CYTH2), transcript variant 1


  "NM_017457" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CYTH2
Synonyms ARNO; CTS18; CTS18.1; cytohesin-2; PSCD2; PSCD2L; SEC7L; Sec7p-L; Sec7p-like
Vector pCMV6-XL6
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC114117 sequence for NM_017457 edited (data generated by NextGen Sequencing)
ATGGAGGACGGCGTCTATGAACCCCCAGACCTGACTCCGGAGGAGCGGATGGAGCTGGAG
AACATCCGGCGGCGGAAGCAGGAGCTGCTGGTGGAGATTCAGCGCCTGCGGGAGGAGCTC
AGTGAAGCCATGAGCGAGGTGGAGGGGCTGGAGGCCAATGAGGGCAGTAAGACCTTGCAA
CGGAACCGGAAGATGGCAATGGGCAGGAAGAAGTTCAACATGGACCCCAAGAAGGGGATC
CAGTTCTTGGTGGAGAATGAACTGCTGCAGAACACACCCGAGGAGATCGCCCGCTTCCTG
TACAAGGGCGAGGGGCTGAACAAGACAGCCATCGGGGACTACCTGGGGGAGAGGGAAGAA
CTGAACCTGGCAGTGCTCCATGCTTTTGTGGATCTGCATGAGTTCACCGACCTCAATCTG
GTGCAGGCCCTCAGGCAGTTTCTATGGAGCTTTCGCCTACCCGGAGAGGCCCAGAAAATT
GACCGGATGATGGAGGCCTTCGCCCAGCGATACTGCCTGTGCAACCCTGGGGTTTTCCAG
TCCACAGACACGTGCTATGTGCTGTCCTTCGCCGTCATCATGCTCAACACCAGTCTCCAC
AATCCCAATGTCCGGGACAAGCCGGGCCTGGAGCGCTTTGTGGCCATGAACCGGGGCATC
AACGAGGGCGGGGACCTGCCTGAGGAGCTGCTCAGGAACCTGTACGACAGCATCCGAAAT
GAGCCCTTCAAGATTCCTGAGGATGACGGGAATGACCTGACCCACACCTTCTTCAACCCG
GACCGGGAGGGCTGGCTCCTGAAGCTGGGAGGGGGCCGGGTGAAGACGTGGAAGCGGCGC
TGGTTTATCCTCACAGACAACTGCCTCTACTACTTTGAGTACACCACGGACAAGGAGCCC
CGAGGAATCATCCCCCTGGAGAATCTGAGCATCCGAGAGGTGGACGACCCCCGGAAACCG
AACTGCTTTGAACTTTACATCCCCAACAACAAGGGGCAGCTCATCAAAGCCTGCAAAACT
GAGGCGGACGGCCGAGTGGTGGAGGGAAACCACATGGTGTACCGGATCTCGGCCCCCACG
CAGGAGGAGAAGGACGAGTGGATCAAGTCCATCCAGGCGGCTGTGAGTGTGGACCCCTTC
TATGAGATGCTGGCAGCGAGAAAGAAGCGGATTTCAGTCAAGAAGAAGCAGGAGCAGCCC
TGA

Clone variation with respect to NM_017457.5
>OriGene 5' read for NM_017457 unedited
CCCGCCCCGTTGACGCAATTGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAG
TTTATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATT
CGGCACGAGGTGAGGAGGCGGCGGTGGCTCCCGGGGCGTTTGAGCGGGCTCACCCGAGCC
CGCGGGCCAACGCGGATCCAGGCCCGACTGGCGGGACCGCCCCGGATTCCCCGCGGGCCT
TCCTAGCCGCCATGGAGGACGGCGTCTATGAACCCCCAGACCTGACTCCGGAGGAGCGGA
TGGAGCTGGAGAACATCCGGCGGCGGAAGCAGGAGCTGCTGGTGGAGATTCAGCGCCTGC
GGGAGGAGCTCAGTGAAGCCATGAGCGAGGTGGAGGGGCTGGAGGCCAATGAGGGCAGTA
AGACCTTGCAACGGAACCGGAAGATGGCAATGGGCAGGAAGAAGTTCAACATGGACCCCA
AGAAGGGGATCCAGTTCTTGGTGGAGAATGAACTGCTGCAGAACACACCCGAGGAGATCG
CCCGCTTCCTGTACAAGGGCGAGGGGCTGAACAAGACAGCCATCGGGGACTACCTTGGGG
AGAGGGAAGAACTGAACCTGGCAGTGCTCCATGCTTTTGTGGATCTGCATGAGTTCACCG
ACCTCAATCTGGTGCAGGCCCTCAGGCAGTTTCTATGGAGCTTTCGCCTACCCGGAGAGG
CCCCAGAAATTGACCGGATGATGGAGGCCTTTCGCCAGCGATACTGCCTGTGCACCCNTG
GGTTTTNCAGTCACAGACACTGCTATGTGCTGTCCTTTCGCGNATCATGCTCACACCAGT
CTNCACATCCNATGTNCGGNACANGCGGNCCTGNAGCGCTTTGTGGCATGACCGNGCATC
ACGAGGGCCGGGACCTGCTGAGAGCTGTCAGAACCTGTCACAGCATCGATGAGCCTTAGA
TCCTGAGTTGACAGGATGACTGACACC
>OriGene 3' read for NM_017457 unedited
TTTTTGGATTTAGCTATGNNACCGCGGCCGCTTNCTANGATCGAGTTTTTTTTTTTTTTT
TTTGCTGGGGGTTAGGATTTTAATATAAAGTTTTTTGTGGGGGTGGGGGAGACACAATTT
GATCCGTGCTGAGTCCATTTTGTGTTGCTCTGACAGAAGACCTGAGGCTGGGTCTTTATA
AAGGAAGAGGTTGATTTGGCTCAGATTCTGATGGCTGGAAGGTTCAAGACTGGGCAGGTG
CACTCACTGAGGACCTCCCTCATCCCTGAGGCTGCTGCTGCTTCTGGGGGAGGGCAGAAG
GATGCAGCTGTGTGCACAGAGATCACATGGTGCTGAAGGAAGCAAGGGAGAGAAAACCAA
ATTCCCAAATTCCCAAGGGTGAGCACTCACTCACCCCTTAAGGCAGGCATTAATCTATCC
ATGAGGACTCCACCTCCAAGACCACACAGCTCCTATGAGGCCCCACATCCCAACACCTGC
CACACTGGGGGCTCGAATCTCAACATGAATTTTAGTGAAGACAAACGATATCCAAACCAT
TGCCACCCAAAAGAAGTGGGGCTGAAGCCTGGCGCGGTGGCTCACACCTGTAATCCCCAC
ACTTTTGGGAGGCTGAAACAAATGGGTCCCCCTGAAGTCAAGAATTTCCAGACCAGCTTG
GGCCATATGGGGAAACCCCCTCTTTTCTAAAATCCCAAATTTGCTGGGTACGGGGCTCCC
ATCTTTAATCCCACTTCCCCGGAAACTTAGCCAGGGAAATCCTTTGCCCTCGGGAGTGGA
GGGTTCACATAAACCCAAATGGCCCCTTTGCCCTCCCGTTTTAGGCACAAATGGTGACCT
CCCTTTCAAAAAAAAAAAAAAAAAAAAAC
Restriction Sites NotI-NotI     
ACCN NM_017457
ORF Size 1203 bp
Insert Size 4700
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_017457.3, NP_059431.1
RefSeq Size 1545
RefSeq ORF 1203
Locus ID 9266
Domains Sec7, PH
Protein Families Druggable Genome
Gene Summary The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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