MVP (NM_017458) Human Untagged Clone

CAT#: SC114118

MVP (untagged)-Human major vault protein (MVP), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MVP
• Synonyms: LRP; VAULT1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_017458 edited
  GAATTCGGCACGAGGGTTGCAGCTACCTGCACTTCTAGATTCATCTTCTTGTGAGCCCTG
  GGCTTAGGAGTCACCATGGCAACTGAAGAGTTCATCATCCGCATCCCCCCATACCACTAT
  ATCCATGTGCTGGACCAGAACAGCAACGTGTCCCGTGTGGAGGTCGGGCCAAAGACCTAC
  ATCCGGCAGGACAATGAGAGGGTACTGTTTGCCCCCATGCGCATGGTGACCGTCCCCCCA
  CGTCACTACTGCACAGTGGCCAACCCTGTGTCTCGGGATGCCCAGGGCTTGGTGCTGTTT
  GATGTCACAGGGCAAGTTCGGCTTCGCCACGCTGACCTCGAGATCCGGCTGGCCCAGGAC
  CCCTTCCCCCTGTACCCAGGGGAGGTGCTGGAAAAGGACATCACACCCCTGCAGGTGGTT
  CTGCCCAACACTGCCCTCCATCTAAAGGCGCTGCTTGATTTTGAGGATAAAGATGGAGAC
  AAGGTGGTGGCAGGAGATGAGTGGCTTTTCGAGGGACCTGGCACGTACATCCCCCGGAAG
  GAAGTGGAGGTCGTGGAGATCATTCAGGCCACCATCATCAGGCAGAACCAGGCTCTGCGG
  CTCAGGGCCCGCAAGGAGTGCTGGGACCGGGACGGCAAGGAGAGGGTGACAGGGGAAGAA
  TGGCTGGTCACCACAGTAGGGGCGTACCTCCCAGCGGTGTTTGAGGAGGTTCTGGATTTG
  GTGGACGCCGTCATCCTTACGGAAAAGACAGCCCTGCACCTCCGGGCTCGGCGGAACTTC
  CGGGACTTCAGGGGAGTGTCCCGCCGCACTGGGGAGGAGTGGCTGGTAACAGTGCAGGAC
  ACAGAGGCCCACGTGCCAGATGTCCACGAGGAGGTGCTGGGGGTTGTGCCCATCACCACC
  CTGGGCCCCCACAACTACTGCGTGATTCTCGACCCTGTCGGACCGGATGGCAAGAATCAG
  CTGGGGCAGAAGCGCGTGGTCAAGGGAGAGAAGTCTTTTTTCCTCCAGCCAGGAGAGCAG
  CTGGAACAAGGCATCCAGGATGTGTATGTGCTGTCGGAGCAGCAGGGGCTGCTGCTGAGG
  GCCCTGCAGCCCCTGGAGGAGGGGGAGGATGAGGAGAAGGTCTCACACCAGGCTGGGGAC
  CACTGGCTCATCCGCGGACCCCTGGAGTATGTGCCATCTGCCAAAGTGGAGGTGGTGGAG
  GAGCGCCAGGCCATCCCTCTAGACGAGAACGAGGGCATCTATGTGCAGGATGTCAAGACC
  GGAAAGGTGCGCGCTGTGATTGGAAGCACCTACATGCTGACCCAGGACGAAGTCCTGTGG
  GAGAAAGAGCTGCCTCCCGGGGTGGAGGAGCTGCTGAACAAGGGGCAGGACCCTCTGGCA
  GACAGGGGTGAGAAGGACACAGCTAAGAGCCTCCAGCCCTTGGCGCCCCGGAACAAGACC
  CGTGTGGTCAGCTACCGCGTGCCCCACAACGCTGCGGTGCAGGTGTACGACTACCGAGAG
  AAGCGAGCCCGCGTGGTCTTCGGGCCTGAGCTGGTGTCGCTGGGTCCTGAGGAGCAGTTC
  ACAGTGTTGTCCCTCTCAGCTGGGCGGCCCAAGCGTCCCCATGCCCGCCGTGCGCTCTGC
  CTGCTGCTGGGGCCTGACTTCTTCACAGACGTCATCACCATCGAAACGGCGGATCATGCC
  AGGCTGCAACTGCAGCTGGCCTACAACTGGCACTTTGAGGTGAATGACCGGAAGGACCCC
  CAAGAGACGGCCAAGCTCTTTTCAGTGCCAGACTTTGTAGGTGATGCCTGCAAAGCCATC
  GCATCCCGGGTGCGGGGGGCCGTGGCCTCTGTCACTTTCGATGACTTCCATAAGAACTCA
  GCCCGCATCATTCGCACTGCTGTCTTTGGCTTTGAGACCTCGGAAGCGAAGGGCCCCGAT
  GGCATGGCCCTGCCCAGGCCCCGGGACCAGGCTGTCTTCCCCCAAAACGGGCTGGTGGTC
  AGCAGTGTGGACGTGCAGTCAGTGGAGCCTGTGGATCAGAGGACCCGGGACGCCCTGCAA
  CGCAGCGTCCAGCTGGCCATCGAGATCACCACCAACTCCCAGGAAGCGGCGGCCAAGCAT
  GAGGCTCAGAGACTGGAGCAGGAAGCCCGCGGCCGGCTTGAGCGGCAGAAGATCCTGGAC
  CAGTCAGAAGCCGAGAAAGCTCGCAAGGAACTTTTGGAGCTGGAGGCTCTGAGCATGGCC
  GTGGAGAGCACCGGGACTGCCAAGGCGGAGGCCGAGTCCCGTGCGGAGGCAGCCCGGATT
  GAGGGAGAAGGGTCCGTGCTGCAGGCCAAGCTAAAAGCACAGGCCTTGGCCATTGAAACG
  GAGGCTGAGCTCCAGAGGGTCCAGAAGGTCCGAGAGCTGGAACTGGTCTATGCCCGGGCC
  CAGCTGGAGCTGGAGGTGAGCAAGGCTCAGCAGCTGGCTGAGGTGGAGGTGAAGAAGTTC
  AAGCAGATGACAGAGGCCATAGGCCCCAGCACCATCAGGGACCTTGCTGTGGCTGGGCCT
  GAGATGCAGGTAAAACTGCTCCAGTCCCTGGGCCTGAAATCAACCCTCATCACCGATGGC
  TCCACTCCCATCAACCTCTTCAACACAGCCTTTGGGCTGCTGGGGATGGGGCCCGAGGGT
  CAGCCCCTGGGCAGAAGGGTGGCCAGTGGGCCCAGCCCTGGGGAGGGGATATCCCCCCAG
  TCTGCTCAGGCCCCTCAAGCTCCTGGAGACAACCACGTGGTGCCTGTACTGCGCTAACTC
  CTGATTAATACAATGGAAGTTTCTGGGCATTTACAATTTCAAAAAAAAAAAAAAAAAACT
  CGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017458 unedited
  TTTGTACTACGATTTACTATAGGGCGGCCGCGCATTCGGCACGAGGGTTGCAGCTACCTG
  CACTTCTAGATTCATCTTCTTGTGAGCCCTGGGCTTAGGAGTCACCATGGCAACTGAAGA
  GTTCATCATCCGCATCCCCCCATACCACTATATCCATGTGCTGGACCAGAACAGCAACGT
  GTCCCGTGTGGAGGTCGGGCCAAAGACCTACATCCGGCAGGACAATGAGAGGGTACTGTT
  TGCCCCCATGCGCATGGTGACCGTCCCCCCACGTCACTACTGCACAGTGGCCAACCCTGT
  GTCTCGGGATGCCCAGGGCTTGGTGCTGTTTGATGTCACAGGGCAAGTTCGGCTTCGCCA
  CGCTGACCTCGAGATCCGGCTGGCCCAGGACCCCTTCCCCCTGTACCCAGGGGAGGTGCT
  GGAAAAGGACATCACACCCCTGCAGGTGGTTCTGCCCAACACTGCCCTCCATCTAAAGGC
  GCTGCTTGATTTTGAGGATAAAGATGGAGACAAGGTGGTGGCAGGAGATGAGTGGCTTTT
  CGAGGGACCTGGCACGTACATCCCCCGGAAGGAAGTGGAGGTCGTGGAGATCATTCAGGC
  CACCATCATCAGGCAGAACCAGGCTCTGCGGCTCAGGGCCCGCAAGGAGTGCTGNGACCG
  NGACGGCAAGGAGAGGGTGACAGGGGAAGAATGGCTGGTCACCACAGTANGGGCGTACCT
  CCCAGCGTGTTGGAAGAGGGTCTGGATTTGGTGGACCCCGCATCCTTACGGAAAGACAGC
  CCTGCACCTCCGGGCTCGGGGGAACTCCGGNACTTCAAGGGGAGGGGNCCGNCCCCTGGN
  NGAGGGAGGGNNGGNCACAGNNNCACGCCCNCNAGCCACCGNCCACAAGGCCNNNNCCAG
  GCCCAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017458 unedited
  AAAAAAACCTTACTTGNACCCGGCCGCATTCTAAGATCGGTTTTTTTTTTTTTTTTTTGA
  AATGTAAATGCCCAAAAACTTCCTTGTATTAATCAGGAGTTAGCGCAGTACAGGCACCAC
  GTGGTTGTCTCCAGGAGCTTGAGGGGCCTGAGCAGACTGGGGGGATATCCCCTCCCCCAG
  GCTGGGCCCACTGGCCACCCTTCTGCCCAGGGGCTGACCCTTGGTGCCCATTCCCAGAAG
  CCCCAAAGCTGGGTTGAAAAAGGTTGACGGCAAGTGGAACCCCCCCCTGATTGAAGGGTT
  GATTTTCACGCCCACGGCACTGGAGCACACTATTTCCTGGTTTTTTAAGCCCCCCCCCCC
  CCCATTGGTCCCTTTTTGGGGGCCGGGGGCCCTTTGTCCCCCTCTCTACAACCCCCCTTG
  GACTCCTTGTTTTCGCGCCCCCCCCCCCTCGCCCCTTTTCCGTCCAACTCTCTGCTCCCT
  CCCCCCACCCCCACCCCTGTACCCCGGTTTCTTAATACCTTCTCCCCTTCCTCCGCCCCT
  CTCTGCCACCTCCCGTGAGCCTCCCCCCCCCTCCTTTTTAACAGCGCGCCACCAACCTGC
  CTCCTTTCTCACTGCGGGCCTCTGACCAACCACCACCACCTCTCCCCCCCCATCCTTTAT
  CTGCTCTCTTTCTCCTCCCCCCATGCTCCTCACCCCCCCCCCCCCGTCCATTCTCACCCG
  TCCTTTTTTTTCTCGCCCATCGCGTCCCGACACCCTCCCCTCTTACTAACAAATTCCCTC
  CCTTCTTACCCCTTTTTCCCTCCCTCTTCACCACTCCGACATACTCCTTTCTTCTTCCCC
  TCTCCTCCCTCCTACTCGGCCCCTCTTTCTTCCTTTTCACCCCCCCCTACCTCTCCCACT
  CTCCTCCACCCGACCTCCTCCCTCCTCCTCTCGCTGCGATCCATTTTACCCATATCTTCC
  ATCCACTCGCTTTCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017458
• ORF Size: 2682 bp
• Insert Size: 2820
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017458.2, NP_059447.2
• RefSeq Size: 2857
• RefSeq ORF: 2682
• Locus ID: 9961
• Domains: Vault
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (1, also known as L-MVP) is the longest transcript. Variants 1 and 2 encode the same isoform 1.