SHC3 (NM_016848) Human Untagged Clone

CAT#: SC114141

SHC3 (untagged)-Human SHC (Src homology 2 domain containing) transforming protein 3 (SHC3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SHC3
• Synonyms: N-Shc; NSHC; RAI; SHCC
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114141 sequence for NM_016848 edited (data generated by NextGen Sequencing)
  ATGCTTCCACGCACCAAGTATAACCGCTTCAGGAATGACTCGGTGACATCGGTCGATGAC
  CTTCTCCACAGCCTGTCGGTGAGCGGCGGCGGAGGCAAGGTTTCGGCGGCGCGCGCGACC
  CCGGCGGCGGCTCCCTACTTGGTGTCCGGCGAGGCGCTGCGCAAGGCGCCCGACGATGGG
  CCCGGCAGCCTGGGCCACCTGCTCCACAAGGTGTCCCACCTGAAACTCTCCAGCTCGGGC
  CTCCGCGGCCTGTCGTCGGCCGCCCGGGAGCGGGCGGGCGCGCGGCTCTCGGGCAGCTGC
  AGCGCGCCCAGCCTGGCCGCCCCGGACGGCAGTGCGCCCTCGGCGCCCCGCGCCCCGGCC
  ATGAGCGCCGCCAGGAAGGGCCGGCCCGGCGACGAGCCGCTGCCCAGGCCCCCTCGGGGG
  GCGCCGCACGCCAGCGACCAGGTGCTGGGGCCCGGAGTCACCTACGTGGTCAAGTACTTG
  GGGTGCATTGAAGTTCTGCGCTCAATGAGGTCTCTTGACTTCAGTACAAGAACACAAATT
  ACCAGGGAAGCCATCAGCCGCGTCTGTGAAGCTGTGCCTGGTGCGAAGGGAGCCTTCAAG
  AAGAGAAAGCCTCCAAGCAAAATGCTGTCCAGCATCTTGGGAAAGAGCAACCTCCAGTTT
  GCGGGAATGAGCATCTCTCTGACCATCTCCACGGCCAGTCTGAACCTGCGAACTCCGGAC
  TCCAAACAGATCATAGCGAATCACCACATGCGGTCCATCTCCTTCGCCTCTGGGGGAGAC
  CCGGACACAACTGACTATGTTGCATATGTGGCTAAGGACCCTGTTAATCGCAGAGCTTGT
  CACATTTTGGAATGCTGTGATGGGCTGGCCCAGGATGTCATCGGCTCCATCGGACAAGCC
  TTTGAGCTCCGGTTTAAGCAATATTTACAGTGTCCTACCAAGATTCCCGCTCTCCATGAT
  CGAATGCAGAGTCTGGATGAGCCATGGACGGAAGAGGAGGGAGATGGCTCAGACCACCCA
  TACTACAACAGCATCCCAAGCAAGATGCCTCCTCCAGGGGGCTTTCTTGATACTAGACTG
  AAACCCAGACCCCATGCTCCTGACACAGCCCAGTTTGCAGGAAAAGAGCAGACTTATTAC
  CAGGGAAGACACTTAGGAGACACTTTTGGCGAAGACTGGCAGCAAACACCTTTAAGGCAA
  GGGTCCTCGGACATCTACAGCACGCCAGAAGGGAAACTGCACGTGGCCCCCACGGGAGAA
  GCACCCACCTACGTCAACACTCAGCAGATCCCACCACAGGCCTGGCCGGCTGCGGTCAGC
  AGTGCTGAGAGCAGCCCGAGGAAAGACCTCTTTGACATGAAACCTTTTGAAGATGCTCTC
  AAGAACCAGCCCTTGGGGCCCGTGTTAAGCAAGGCAGCCTCCGTGGAGTGCATCAGCCCT
  GTGTCACCTAGAGCCCCAGATGCCAAGATGCTGGAGGAACTGCAAGCCGAGACTTGGTAC
  CAAGGAGAGATGAGCAGGAAGGAGGCAGAGGGGCTGCTGGAGAAAGACGGAGACTTCCTG
  GTCAGGAAGAGCACCACCAACCCGGGCTCCTTTGTCCTCACGGGCATGCACAATGGCCAG
  GCCAAGCACCTGCTGCTCGTGGACCCAGAAGGCACGATCCGGACAAAGGACAGAGTCTTT
  GACAGTATCAGCCACCTCATCAACCACCACCTAGAAAGCAGCCTGCCCATTGTCTCTGCA
  GGGAGTGAGCTGTGTCTCCAGCAGCCAGTGGAGAGGAAGCAGTGA
  
  Clone variation with respect to NM_016848.5
  1338 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016848 unedited
  NGGGTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTCAGAG
  TGAGTCATGCTTTTGCTGTGAGCAGCCCCAAGCAGCTGGGCGCTCCATCAGAGGCAACTA
  TGACTTTTGCAAAGCAAACGTGCAACCCCAAGCAGCGGTCTCCCGGGCCGGGGCTGCGCG
  GCCGCCGCTGTGCTGGCTTTTAACGGTGGGAGGGCACCATCCTCTTGCTCTGCTCTCGTT
  CTCCAGAAGGCTGTCCCGGGGCCCCCACTCTCCGTCCCGCTCCGGGGACAGTGGCTCGCC
  TGCTATGCGCGGCAGCCCGCGCCGGGGCCGGCACCAGCAGCGCCCGGGCGGATGCAGCGA
  GCCCACGGAGGGGCATGCTTCCACGCACCAAGTATAACCGCTTCAGGAATGACTCGGTGA
  CATCGGTCGATGACCTTCTCCACAGCCTGTCGGTGAGCGGCGGCGGAGGCAAGGTTTCGG
  CGGCGCGCGCGACCCCGGCGGCGGCTCCCTACTTGGTGTCCGGCGAGGCGCTGCGCAAGG
  CGCCCGACGATGGGCCCGGCAGCCTGGGCCACCTGCTCCACAAGGTGTCCCACCTGAAAC
  TCTCCAGCTCGGGCCTCCGCGGCCTGTCGTCGGCCGCCCGGAGCNNGGCCCGGGCGCGCG
  GATTCTCGGGCAGCTGCAGCGCGCCCAGCCTGGCCGCCCCGGACGGCAGTGCGCCCTCGG
  CGCCCCGCGCCCCGGCCATGAGCGCCGNCAGGAAAGGGCCGGCCCGGCGACGAGCCGCTG
  CCCAGCCCCCTTCGGGGGGCGCCGCACGCCACGACCAGGTGCTGGGCCCCCGGAGCACCT
  ACGTGGGTCAGTCTTTGGGTGCATATGGAAGTTCTGCGCTCAATGAGGTCTCCTGACTTC
  AGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016848 unedited
  TGTCTCTGGGAACGCGGCACGCATTCTAGGATCGAGTTTTTTTTTTTTTTTTTTCATTAA
  AAACACACAGCACAGACATTAGTCTTACATCTTTCTTAGTCTTAAAAAATATAAATATAG
  AGGGATAATTTGTACAGGATGTATAGGTATGTACACCTTTAATATGCATATGAGAAATTC
  AGAACCAAGTTTATGAAACTTGACCTTAAAGGAAGCCTTCCTTTTGAAGCTTTTGAAGAA
  GGCTCTGAGCCACAGGCAGCTGTCCCAGTTCCAGCAGCCCCGATTCTAGTCCACTCCAGG
  TCCTCCTGACCTGGTGCGCAGTGCTGGGAGCAGTGCTGGCCAGGTCACTGCTTCCTCTCC
  ACTGGCTGCTGGAGACACAGCTCACTCCCTGCAGAGACAATGGGCAGGCTGCTTTCTAGG
  TGGTGGTTGATGAGGTGGCTGATACTGTCAAAGACTCTGTCCTTTGTCCGGATCGTGCCT
  TCTGGGTCCACGAGCAGCAGGTGCTTGGCCTGGCCATTGTGCATGCCCGTGAGGACAAAG
  GAGCCCGGGTTGGNTGGTGCTCTTCCTGACCAGGAAGTCTCCGTCTTTCTCCAGCAGCCC
  CTCTGCCTCCTTCCTGCTCATCTCTCCTTGGTACCAAGTCTCGCCTTGCAGTTCCTCCAG
  CATCTTGGCATCTGGGGCTCTAGGTGACACAGGGCTGATGCACTCCACGGAGGCTGCCTT
  GCTTACACGGGCCCCAAGGGCTGGTTCTTGAGAGCATCTTCAAAAGGTTTCATGTCAAAG
  AGGTCTTTTCCTCGGGCTGGTCTCAACACTGCTGACCGNANCCGGCCCAGCCTGTGGGGG
  GGGATCTGCTGAGGTGTGACGTAAGGGGGTGCTTTCCCCCGGGGGGCCACGGGCAGTTTC
  CTTTTGGCGTGCTGAAAAGTCCGAGGACCTTGCCTTAAAAGGGTTGCTGCAATTTTCCCC
  AAGAGGTTTCTAGGGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016848
• ORF Size: 1785 bp
• Insert Size: 2240
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016848.2, NP_058544.2
• RefSeq Size: 2400
• RefSeq ORF: 1785
• Locus ID: 53358
• Domains: SH2, PID
• Protein Pathways: Chemokine signaling pathway, Chronic myeloid leukemia, ErbB signaling pathway, Focal adhesion, Glioma, Insulin signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway
• Gene Summary: Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. [UniProtKB/Swiss-Prot Function]