WWOX (NM_016373) Human Untagged Clone

CAT#: SC114305

WWOX (untagged)-Human WW domain containing oxidoreductase (WWOX), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WWOX
• Synonyms: D16S432E; EIEE28; FOR; FRA16D; HHCMA56; PRO0128; SCAR12; SDR41C1; WOX1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_016373 edited
  ATGGCAGCGCTGCGCTACGCGGGGCTGGACGACACGGACAGTGAGGACGAGCTGCCTCCG
  GGCTGGGAGGAGAGAACCACCAAGGACGGCTGGGTTTACTACGCCAATCACACCGAGGAG
  AAGACTCAGTGGGAACATCCAAAAACTGGAAAAAGAAAACGAGTGGCAGGAGATTTGCCA
  TACGGATGGGAACAAGAAACTGATGAGAACGGACAAGTGTTTTTTGTTGACCATATAAAT
  AAAAGAACCACCTACTTGGACCCAAGACTGGCGTTTACTGTGGATGATAATCCGACCAAG
  CCAACCACCCGGCAAAGATACGACGGCAGCACCACTGCCATGGAAATTCTCCAGGGCCGG
  GATTTCACTGGCAAAGTGGTTGTGGTCACTGGAGCTAATTCAGGAATAGGGTTCGAAACC
  GCCAAGTCTTTTGCCCTCCATGGTGCACATGTGATCTTGGCCTGCAGGAACATGGCAAGG
  GCGAGTGAAGCAGTGTCACGCATTTTAGAAGAATGGCATAAAGCCAAGGTAGAAGCAATG
  ACCCTGGACCTCGCTCTGCTCCGTAGCGTGCAGCATTTTGCTGAAGCATTCAAGGCCAAG
  AATGTGCCTCTTCATGTGCTTGTGTGCAACGCAGCAACTTTTGCTCTACCCTGGAGTCTC
  ACCAAAGATGGCCTGGAGACCACCTTTCAAGTGAATCATCTGGGGCACTTCTACCTTGTC
  CAGCTCCTCCAGGATGTTTTGTGCCGCTCAGCTCCTGCCCGTGTCATTGTGGTCTCCTCA
  GAGTCCCATCGATTTACAGATATTAACGACTCCTTGGGAAAACTGGACTTCAGTCGCCTC
  TCTCCAACAAAAAACGACTATTGGGCGATGCTGGCTTATAACAGGTCCAAGCTCTGCAAC
  ATCCTCTTCTCCAACGAGCTGCACCGTCGCCTCTCCCCACGCGGGGTCACGTCGAACGCA
  GTGCATCCTGGAAATATGATGTACTCCAACATTCATCGCAGCTGGTGGGTGTACACACTG
  CTGTTTACCTTGGCGAGGCCTTTCACCAAGTCCATGCAACAGGGAGCTGCCACCACCGTG
  TACTGTGCTGCTGTCCCAGAACTGGAGGGTCTGGGAGGGATGTACTTCAACAACTGCTGC
  CGCTGCATGCCCTCACCAGAAGCTCAGAGCGAAGAGACGGCCCGGACCCTGTGGGCGCTC
  AGCGAGAGGCTGATCCAAGAACGGCTTGGCAGCCAGTCCGGCTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016373 unedited
  TCACATTTGTATCCGACTCACTATAGGGNNCGGCCGCGCAATTCGGCACGAGGGTCGGGC
  CCCGACGCGCGCGGGTCTCGTTTGGAGCGGGAGTGAGTTCCTGAGCGAGTGGACCCGGCA
  GCGGGCGATAGGGGGGCCAGGTGCCTCCACAGTCAGCCATGGCAGCGCTGCGCTACGCGG
  GGCTGGACGACACGGACAGTGAGGACGAGCTGCCTCCGGGCTGGGAGGAGAGAACCACCA
  AGGACGGCTGGGTTTACTACGCCAATCACACCGAGGAGAAGACTCAGTGGGAACATCCAA
  AAACTGGAAAAAGAAAACGAGTGGCAGGAGATTTGCCATACGGATGGGAACAAGAAACTG
  ATGAGAACGGACAAGTGTTTTTTGTTGACCATATAAATAAAAGAACCACCTACTTGGACC
  CAAGACTGGCGTTTACTGTGGATGATAATCCGACCAAGCCAACCACCCGGCAAAGATACG
  ACGGCAGCACCACTGCCATGGAAATTCTCCAGGGCCGGGATTTCACTGGCAAAGTGGTTG
  TGGTCACTGGAGCTAATTCAGGAATAGGGTTCGAAACCGCCAAGTCTTTTGCCCTCCATG
  TTGCACATGTGATCTTTGCCTGCAGGAACATGGCAAGGGCGAGTGAAGCAGTGCCACGCA
  TTTTAGAAGAATGGCATAAAGCCAAGGTAGAAGCAATGACCCTGGACCTCGCTCTGCTCC
  GTAACGTGCAGCATTTTTGCTGAAGCATTCAAAGCCCNGAATGTGCCTCCTTATGTGCTT
  GTGTGCAACGCACCAACTTTTGCTCTACCCTGGAGTCTCACCCAAGATGGCCTGGAGACC
  ACCTTTCAGATGAATCATTTGGGGGCACTTTTACCTTGTCCAGCTCCTTCAAGAAGTNTT
  GGGGCCCTTAACTTCTGCCCGGGTCATTGTGGTCTCCTCAGAACN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016373 unedited
  CGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGATATTCAAGCATGTTCTT
  TTATTAAGCGTAGGATGCGAGGCACAGCAGGAGGTTTAAGTACAATGTGAAAGCAAGAGA
  ACTGAGACTGTGATTGACAGACAAAGGGATTAACTAACGTTTTATTCTCTGCCCCCCAAA
  ATATCCTGTGTATTCTTAAGTATATACGCTTCCCTTCCTGCCTTTCAAGGTATCTAAGGA
  ATGATTTGAAAAATTTGTTATAATCTCTAAAGAATTTTTTGTATAGCATTAGCAAAGGAG
  TCTATGACAAGTACTTTGCCACCTGGTAGTTCTGCGTATTCTACTCCCTCTGGGTGTCAC
  TGTCATCCTCACTGGCTGGGACAAGGTTCTGAGATTTGTCTCCCCAGCAGTTGCTAAGCT
  GGCTCAGTCTTGGTCAGGATGAATGAAACAATTATCTCCTGGATCAATGCAGCAAGGAGC
  AGTGAACACTTGCTTTTTCTTCCCTAAGTAGGAGAAGGCCAGCCCCTGGCTGCAGTGGTG
  GCCGTGGTGGTAGCTGGATGGGACGAGGGGACCTCAGGCTATTCTATAACAGTAAAAGAA
  AGAGAATTGCTGGTGCTTCTCCAGGGAGATACGGAACCTACACGCCAACCAGGTTTTTAC
  TTTCAAACAGGCCACCACCAGAAAGCAAAGAGACTATGCCTAGCCCAGCCCAGAAAGTGA
  TACTNNTACCCCAGAATTCCCCTGCTTCCCATTGTACTTAAGATTNTTCACTCTGNTGGG
  AATGCTNCTATTNCCTTTNACTCTGCNGATCTGTGTGGNAGGNACATTNGNAAGGGGGCC
  ANCCNTGNCACTNGCGTGAGGGGACCACACAGGNNNCGGTGGGTGTGGCCCANCCCGCTC
  TGAGCTCACTTTACCGACTGGCTGNNCAGCCGTNCTTGGATCANCCCTCCCTGGACGCCC
  CAGGNT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016373
• ORF Size: 1245 bp
• Insert Size: 2380
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016373.1, NP_057457.1
• RefSeq Size: 2264
• RefSeq ORF: 1245
• Locus ID: 51741
• Domains: WW, adh_short
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).