Aminoadipate aminotransferase (AADAT) (NM_016228) Human Untagged Clone

CAT#: SC114349

AADAT (untagged)-Human aminoadipate aminotransferase (AADAT), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AADAT
• Synonyms: KAT2; KATII; KYAT2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114349 sequence for NM_016228 edited (data generated by NextGen Sequencing)
  ATGAATTACGCACGGTTCATCACGGCAGCGAGCGCAGCCAGAAACCCTTCTCCCATCCGG
  ACCATGACTGACATATTGAGCAGAGGACCAAAATCGATGATCTCCTTGGCTGGTGGCTTA
  CCAAATCCAAACATGTTTCCTTTTAAGACTGCCGTAATCACTGTAGAAAATGGAAAGACC
  ATCCAATTTGGAGAAGAGATGATGAAGAGAGCACTTCAGTATTCTCCGAGTGCTGGAATT
  CCAGAGCTTTTGTCCTGGCTAAAACAGTTACAAATAAAATTGCATAATCCTCCTACCATC
  CATTACCCACCCAGTCAAGGACAAATGGATCTATGTGTCACATCTGGCAGCCAACAAGGT
  CTTTGTAAGGTGTTTGAAATGATCATTAATCCTGGAGATAATGTCCTCCTAGATGAACCT
  GCTTATTCAGGAACTCTTCAAAGTCTGCACCCACTGGGCTGCAACATTATTAATGTTGCC
  AGTGATGAAAGTGGGATTGTTCCAGATTCCCTAAGAGACATACTTTCCAGATGGAAACCA
  GAAGATGCAAAGAATCCCCAGAAAAACACCCCCAAATTTCTTTATACTGTTCCAAATGGC
  AACAACCCTACTGGAAACTCATTAACCAGTGAACGCAAAAAGGAAATCTATGAGCTTGCA
  AGAAAATATGATTTCCTCATAATAGAAGATGATCCTTACTATTTTCTCCAGTTTAACAAG
  TTCAGGGTACCAACATTTCTTTCCATGGATGTTGATGGACGTGTCATCAGAGCTGACTCT
  TTTTCAAAAATCATTTCCTCTGGGTTGAGAATAGGATTTTTAACTGGTCCAAAACCCTTA
  ATAGAGAGAGTTATTTTACACATACAAGTTTCAACATTGCACCCCAGCACTTTTAACCAG
  CTCATGATATCACAGCTTCTACACGAATGGGGAGAAGAAGGTTTCATGGCTCATGTAGAC
  AGGGTTATTGATTTCTATAGTAACCAGAAGGATGCAATACTGGCAGCTGCAGACAAGTGG
  TTAACTGGTTTGGCAGAATGGCATGTTCCTGCTGCTGGAATGTTTTTATGGATTAAAGTT
  AAAGGCATTAATGATGTAAAAGAACTGATTGAAGAAAAGGCCGTTAAGATGGGGGTATTA
  ATGCTCCCTGGAAATGCTTTCTACGTCGATAGCTCAGCTCCTAGCCCTTACTTGAGAGCA
  TCCTTCTCTTCAGCTTCTCCAGAACAGATGGATGTGGCCTTCCAGGTATTAGCACAACTT
  ATAAAAGAATCTTTATGA
  
  Clone variation with respect to NM_016228.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016228 unedited
  ACTATAGGGCGGCCGCGAATTCGGCACGAGGCGGCCGCAGGAGCGCGTGCGGCGTGGACT
  TTGCCGGGCTCGCCACACAGCCCCAGACCCGTTTAGGACCGGGAGACCGAACGCAGCGTC
  CAGCCGGGGAGTTTCGGCGGCGTTCTCCGGGCACCGCGCGCGGGAAGCCAGACGCAGCGG
  GGGGACACATCTCGCGGTGGCGTTGCCAGAGTGAGGAGTTAGCAGGCAGGACTTGACGAG
  GCTCTTTGGTTTTTCTAGTCCTCAACCACTGAAGAAGAAGCTTGATGCTTGGCTGTCAGA
  AGACATGAATTACGCACGGTTCATCACGGCAGCGAGCGCAGCCAGAAACCCTTCTCCCAT
  CCGGACCATGACTGACATATTGAGCAGAGGACCAAAATCGATGATCTCCTTGGCTGGTGG
  CTTACCAAATCCAAACATGTTTCCTTTTAAGACTGCCGTAATCACTGTAGAAAATGGAAA
  GACCATCCAATTTGGAGAAGAGATGATGAAGAGAGCACTTCAGTATTCTCCGAGTGCTGG
  AATTCCAGAGCTTTTGTCCTGGCTAANACAGTTACAAATAAAATTGCATAATCCTTCTAC
  CATCCATTACCCACCCAGTCAAGGACAAATGGATCTATGTGTCACATCTGGCAGCCAACA
  GGTCTTTGTAAAGTGTTTGAATGATCATTATCCTGGAGATATGTCCTCCTAGATGACCTG
  CTTATCANNGACTCTTCAAGTCTGCCCCACTGGGCTGCACATATTTATGTTGCCGTGATG
  AAGTGGGATTGTCCAGATCCCTAGAGACATACTTTCAGATGGAACCCAGAGATGCAAGAA
  TCCAGAAAACACCCCAATTTCCTATACTGTTCAATGGGCACACCTCCTGAAACTCATACA
  GTGACGCAAAGGATCTTTGACTGCAGAAATGATTCTCTATANAGAGATCTACTATTCTCG
  NTACAGTGAGGTCCN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016228 unedited
  GGGGGGGGGGCAGGNAAAAACGAATAAAAACAGAGGNGGTGGGGGTTCAGCATCCTATTT
  AAGGCATTTCTGTGGCATAACATAAGGTTTATGGTACTTTTACTAAAAGTCACTTATAAT
  GACCAAATTATAACAATTTTTGCAATAAGCTCTCATTAAATTTTCCTAAAAGTAGAAAAA
  GTACACATTATATACCATTTTGCACTTAATTACTTCTTTAAAATCTCAAAATAATTCAGT
  GTAAAATGTTAGTTTCAAAGACAATTTATGGGAAATTACAAAGCAACTACAAAGTTCTTC
  ATAATAAATCCAAGATAAAAGTAACTTTTTACAGGTTGAAAGTTTTTCAAAATGCCTAAG
  TGGATTATAAATACAGTTTGGCCATCTGATGAATTTAGAGGCACTTTAAAAGGTGTCTAG
  TTGAACTACTACAGATAGGACATGTTTGAGGAAATTTAATCTTTAAGTCTAATACCAGTG
  TTCATTTCTTCCTGCCAAAACAAGAAATTTATTGGAAAAATCCATGAGCAGCATGATTAG
  TTTGATTTCTTTCTCTTTTTTTAGAGACAGGGTCTTGTTCTGCCATGCAAGCCAGAGTGC
  ATGCAGGCCAGAGAGCAGTGGTGCGATCGTAGCTTACTGCAGCCTTGAATTCCTGGGATT
  AAGTGATCCTACCTCCTGTGACTTACAAAGTGCTGGGACTATACGTGGGAGCCCCCATGC
  CCAACCTACTTTAATTTCTTCATAAAGAATTCTTTTATAGGTGGGCTAATACCTGGAAGG
  CGCCAATCCCTCTGTTTCTGGAAAGTCTGAACAACAAGGATGCTCTTCAAGTTAGGAGCT
  ACGAGCTGATCTATTCCCCTGATAAAGCCTTCCCAGGGCCCCTCTCTACCCCCCTCCTAC
  GGGCTCTTTTCTTAATCAACGATCTTCATCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016228
• ORF Size: 1278 bp
• Insert Size: 2300
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016228.3, NP_057312.1
• RefSeq Size: 2326
• RefSeq ORF: 1278
• Locus ID: 51166
• Protein Pathways: Lysine biosynthesis, Lysine degradation, Metabolic pathways, Tryptophan metabolism
• Gene Summary: This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
  Transcript Variant: This variant (1) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of the first coding exon compared to variant 3. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 1, 2, and 4 all encode the same isoform (b).