DKK3 (NM_015881) Human Untagged Clone

CAT#: SC114569

DKK3 (untagged)-Human dickkopf homolog 3 (Xenopus laevis) (DKK3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DKK3
• Synonyms: REIC; RIG
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114569 sequence for NM_015881 edited (data generated by NextGen Sequencing)
  ATGCAGCGGCTTGGGGCCACCCTGCTGTGCCTGCTGCTGGCGGCGGCGGTCCCCACGGCC
  CCCGCGCCCGCTCCGACGGCGACCTCGGCTCCAGTCAAGCCCGGCCCGGCTCTCAGCTAC
  CCGCAGGAGGAGGCCACCCTCAATGAGATGTTCCGCGAGGTTGAGGAACTGATGGAGGAC
  ACGCAGCACAAATTGCGCAGCGCGGTGGAAGAGATGGAGGCAGAAGAAGCTGCTGCTAAA
  GCATCATCAGAAGTGAACCTGGCAAACTTACCTCCCAGCTATCACAATGAGACCAACACA
  GACACGAAGGTTGGAAATAATACCATCCATGTGCACCGAGAAATTCACAAGATAACCAAC
  AACCAGACTGGACAAATGGTCTTTTCAGAGACAGTTATCACATCTGTGGGAGACGAAGAA
  GGCAGAAGGAGCCACGAGTGCATCATCGACGAGGACTGTGGGCCCAGCATGTACTGCCAG
  TTTGCCAGCTTCCAGTACACCTGCCAGCCATGCCGGGGCCAGAGGATGCTCTGCACCCGG
  GACAGTGAGTGCTGTGGAGACCAGCTGTGTGTCTGGGGTCACTGCACCAAAATGGCCACC
  AGGGGCAGCAATGGGACCATCTGTGACAACCAGAGGGACTGCCAGCCGGGGCTGTGCTGT
  GCCTTCCAGAGAGGCCTGCTGTTCCCTGTGTGCACACCCCTGCCCGTGGAGGGCGAGCTT
  TGCCATGACCCCGCCAGCCGGCTTCTGGACCTCATCACCTGGGAGCTAGAGCCTGATGGA
  GCCTTGGACCGATGCCCTTGTGCCAGTGGCCTCCTCTGCCAGCCCCACAGCCACAGCCTG
  GTGTATGTGTGCAAGCCGACCTTCGTGGGGAGCCGTGACCAAGATGGGGAGATCCTGCTG
  CCCAGAGAGGTCCCCGATGAGTATGAAGTTGGCAGCTTCATGGAGGAGGTGCGCCAGGAG
  CTGGAGGACCTGGAGAGGAGCCTGACTGAAGAGATGGCGCTGAGGGAGCCTGCGGCTGCC
  GCCGCTGCACTGCTGGGAGGGGAAGAGATTTAG
  
  Clone variation with respect to NM_015881.5
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015881 unedited
  AGGTCAAATTTGTATACGACTCCTATAGGCGGCCGGCGAATCGGCACGAGGACAGGCGGC
  GGCTGCGGGCGCAGAGCGGAGATGCAGCGGCTTGGGGCCACCCTGCTGTGCCTGCTGCTG
  GCGGCGGCGGTCCCCACGGCCCCCGCGCCCGCTCCGACGGCGACCTCGGCTCCAGTCAAG
  CCCGGCCCGGCTCTCAGCTACCCGCAGGAGGAGGCCACCCTCAATGAGATGTTCCGCGAG
  GTTGAGGAACTGATGGAGGACACGCAGCACAAATTGCGCAGCGCGGTGGAAGAGATGGAG
  GCAGAAGAAGCTGCTGCTAAAGCATCATCAGAAGTGAACCTGGCAAACTTACCTCCCAGC
  TATCACAATGAGACCAACACAGACACGAAGGTTGGAAATAATACCATCCATGTGCACCGA
  GAAATTCACAAGATAACCAACAACCAGACTGGACAAATGGTCTTTTCAGAGACAGTTATC
  ACATCTGTGGGAGACGAAGAAGGCAGAAGGAGCCACGAGTGCATCATCGACGAGGACTGT
  GGGCCCAGCATGTACTGCCAGTTTGCCAGCTTCCAGTACACCTGCCAGCCATGCCGGGGC
  CAGAGGATGCTCTGCACCCGGGACAGTGAGTGCTGTGGAGACCAGCTGTGTGTCTGGGGT
  CACTGCACCAAAATGGCCACCAGGGGCAGCAATGGGACCATCTGTGACAACCAGAGGGAC
  TGCCAGCCGGNGCTGTGCTGTGCCTTCCAGAGAGGCCTGCTGTTCCCTGTGTGCACACCC
  CTGCCCGTGGAGGGCGAGCTNTGCCATGACCCCGCCAGCCGGCTTCTGGACCTCATCACC
  TGGGAGCTAGAGCCTGATGGAGCCTTGGACCGATGCCCCTGTGCCAGTGGCCTCCTCTGC
  CAGCCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015881 unedited
  TGGAGTGCTTTATGCTTGGTTTCTAAAGGCAACTTATGTTTATACATAATTTAAAACTCA
  AGNAAAGCATGCTTATACAATCATGTGCAACTTTAAACTTTAAGAACTCTGGATGAATAC
  ATGGTGGCAACAGTCCATGACACCTGAAAACATCATTTGTGGAGTGGCGTAGAGTTCAGT
  GTTCGCAGTCGCATATTACAACCATGTTTCACACAGCCCTGCTCGGTTTGATTTTCTCCA
  CGTGGTTGATAATTGTCTTCAGTTGCTGCTAAGTGATTTTGCAAATTTCATTTATAATCC
  TCGCCCTACAATTACCTAAGTACTGTTTCTGCAGGTTAACCTGTATGCTACGCTCAGTCA
  TATACCTTTCAAAGTTACTAATGCAACTGCCAAAGAGGGACAGTGTCAATATCATTGTCT
  TCATTAGAAGGACGGCTGCCCCACACTGTGAGAACACTGCTGTTCCTAACAGTAGTTTAC
  TTTTAGAGGGATGTGAGAATTAGTTTGACCTTAATTCCAGATGTGCATGCCTCAAAAGAA
  AAATCCCATTCTCCTTCCTTTTGGGGAGCACTTTTGGTGGCACCAAGGCTGGTGTGGGGT
  AGTGGAGAGAGCACTGAGCTTAGAGTCACAACCAGATGAAACTGCTCTGGTCTTCACTAG
  CTGTGTGACTTGNGCAAGCAGCTTGCAGTCTCTGAGCCTCTGAGATCCCTGATGGACGAG
  GAGAACAAATGACCCCTCCCCAGGCTGTGCTGAGAGAAGGAATTGATCTTGGATATGAAA
  TGCTGCCCTGGCACAGAGTAGGAGCTGAGCACACTGCTGGATGAATANCACATNGTATGC
  AGGNNTGACAGNACATTTCATCCTGCACAGCTGAAAGCACAGCTTACCTATGCCCATGGN
  AAGAACTGCGTGNAAAATCCATTTGTGCATTTTTGCCAGNNTGATGTTGCAAGCAGGGCA
  CTCTTTTTCAATTTTCCCAAAACAATCAAGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015881
• ORF Size: 1053 bp
• Insert Size: 2850
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_015881.5, NP_056965.3
• RefSeq Size: 2769
• RefSeq ORF: 1053
• Locus ID: 27122
• Domains: dickkopf_N
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2, and 3 encode the same protein.