ERp19 (TXNDC12) (NM_015913) Human Untagged Clone

CAT#: SC114591

TXNDC12 (untagged)-Human thioredoxin domain containing 12 (endoplasmic reticulum) (TXNDC12)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TXNDC12
• Synonyms: AG1; AGR1; ERP16; ERP18; ERP19; hAG-1; hTLP19; PDIA16; TLP19
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114591 sequence for NM_015913 edited (data generated by NextGen Sequencing)
  ATGGAGACGCGGCCTCGTCTCGGGGCCACCTGTTTGCTGGGCTTCAGTTTCCTGCTCCTC
  GTCATCTCTTCTGATGGACATAATGGGCTTGGAAAGGGTTTTGGAGATCATATTCATTGG
  AGGACACTGGAAGATGGGAAGAAAGAAGCAGCTGCCAGTGGACTGCCCCTGATGGTGATT
  ATTCATAAATCCTGGTGTGGAGCTTGCAAAGCTCTAAAGCCCAAATTTGCAGAATCTACG
  GAAATTTCAGAACTCTCCCATAATTTTGTTATGGTAAATCTTGAGGATGAAGAGGAACCC
  AAAGATGAAGATTTCAGCCCTGACGGGGGTTATATTCCACGAATCCTTTTTCTGGATCCC
  AGTGGCAAGGTGCATCCTGAAATCATCAATGAGAATGGAAACCCCAGCTACAAGTATTTT
  TATGTCAGTGCCGAGCAAGTTGTTCAGGGGATGAAGGAAGCTCAGGAAAGGCTGACGGGT
  GATGCCTTCAGAAAGAAACATCTTGAAGATGAATTGTAA
  
  Clone variation with respect to NM_015913.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015913 unedited
  TTGGGATTTGTAATCCGACTTCACTATAGGCGGCCGCGCAATTCGCACGAGGGGGAAGTA
  GAGGTGTTGTGCTGAGCGGCGCTCGGCGAACTGTGTGGACCGTCTGCTGGGACTCCGGCC
  CTGCGTCCGCTCAGCCCCGTGGCCCCGCGCACCTACTGCCATGGAGACGCGGCCTCGTCT
  CGGGGCCACCTGTTTGCTGGGCTTCAGTTTCCTGCTCCTCGTCATCTCTTCTGATGGACA
  TAATGGGCTTGGAAAGGGTTTTGGAGATCATATTCATTGGAGGACACTGGAAGATGGGAA
  GAAAGAAGCAGCTGCCAGTGGACTGCCCCTGATGGTGATTATTCATAAATCCTGGTGTGG
  AGCTTGCAAAGCTCTAAAGCCCAAATTTGCAGAATCTACGGAAATTTCAGAACTCTCCCA
  TAATTTTGTTATGGTAAATCTTGAGGATGAAGAGGAACCCAAAGATGAAGATTTCAGCCC
  TGACGGGGGTTATATTCCACGAATCCTTTTTCTGGATCCCAGTGGCAAGGTGCATCCTGA
  AATCATCAATGAGAATGGAAACCCCAGCTACAAGTATTTTTATGTCAGTGCCGAGCAAGT
  TGTTCAGGGGATGAAGGAAGCTCATGATAGGCTGACGGGTGATGCCTTCAGATAGATACA
  TCTTGAAGATGAATTGGTACATGAATGTGCCCCTTCTTTCATCAGAGTTAGTGTTCTGGA
  ANGGAAGCAGCAGGGAAGGGATATTGANGAATCATCTAGAACAATTAGCCGACCAGGAAA
  CCTCATTCCTACCTACACTGGAAAGAGCGCTCTCACTGTGGAAAAGTTCTGCTAACAGAA
  GCTGGTCTGCATGTTTGTGGTATCCAGCGGAGAGTGGCAGACTTTTCTCTCCTTTTCCTC
  TNACCTAATGTCAACTGGCATGGATG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015913 unedited
  GTTGAATGCGCCCGCTGNCTANANNCGAAAAATTTTTTTTTTTTTTTGTTAATGCCAGTT
  CAAAAAACAGTTGATGACTTGACAAAATGGCTACACCTAGGGCTTGAAGGTTTGAGTTTC
  TCCAACAGTAACAAGGGAAAGCATGCTTCCACCTGGAGCCGAGTCCAAGCACACAGCCAG
  TCCTGCACACGCATGCGTGCAAACAGGGAAGCTCAAGCATGAGAAGAGGAAAGAGGCTGT
  AGAAATTTGGGAAGAAGCCCACAATTATTCCCAGGAGAAAAAAGGGAAAAAACAGGCTGA
  TATCCTTGGTAGGGGGTAGAATAACTGATTTACACTTAGGATTTATTGTTATTGTTGTTG
  TTGTTGTTTTTTAATGATAAGCTACTTCTGCAATTTTAACGTTGTAGAAAAGATGCTACT
  AGTCTCCTTTCACCACTAAGGTGAGTAAAGTGGGAGGAAATGGGAAAAGACTCAAATACT
  TAAGTGCGAGGAGTAAACATCCAAGTGGCTCAAGTTTTGTGTCAGAAGGTTTCATTCTTT
  ACATTCAATGACAAGTTGACATTTAGGTGAGAGGGAAAAGGAGAAGAAAGTCTGCCACTC
  TCCGCTGGATCCACAAACATGCAGACCAGCTTCTGTTAGCAGAACTCTTCCACAGTGAGA
  GCGCTCCTTTCAGTGTANGTAGGAATGAGGTTTCCTGGTCGGCTTAATTGTTCTAGATGA
  TTCCTCAATATTCCCTTNCCTGCTNGCTTCCTTTCAGAACACTAACTCTGATGAAAGAAG
  GNGCACATTTCTGTTACCATTCATCCTCCAGATGTTTCTTTCTGAAAGGCATCACCCGTC
  AGCCTTTTCTGAGCTTCCTTCATCCCTGACAACTTGCTCCGCACTGACATAAAATACTNG
  NAGCCTGGGCTTCCATTTTCATTGAGAATTCAGGATGCCCCTGCCACTGGATCANAAAAG
  GATCGGGAAAATACCCCGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015913
• ORF Size: 519 bp
• Insert Size: 1430
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015913.2, NP_056997.1
• RefSeq Size: 1616
• RefSeq ORF: 519
• Locus ID: 51060
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Glutathione metabolism
• Gene Summary: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]
  Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.