SPG3A (ATL1) (NM_015915) Human Untagged Clone

CAT#: SC114592

ATL1 (untagged)-Human atlastin GTPase 1 (ATL1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATL1
• Synonyms: AD-FSP; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_015915 edited
  ATGGCCAAGAACCGCAGGGACAGAAACAGTTGGGGTGGATTTTCGGAAAAGACATATGAA
  TGGAGCTCAGAAGAGGAGGAGCCAGTGAAAAAGGCAGGACCAGTCCAAGTCCTCATTGTC
  AAAGATGACCATTCCTTTGAGTTAGATGAAACTGCATTAAATCGGATCCTTCTCTCGGAG
  GCTGTCAGAGACAAGGAGGTTGTTGCTGTATCTGTTGCTGGAGCATTTAGAAAAGGAAAA
  TCATTCCTGATGGACTTCATGTTGAGATACATGTACAACCAGGAATCAGTTGATTGGGTT
  GGAGACTACAATGAACCATTGACTGGTTTTTCATGGAGAGGTGGATCTGAACGAGAGACC
  ACAGGAATTCAGATATGGAGTGAAATCTTCCTTATCAATAAACCTGATGGTAAAAAGGTT
  GCAGTGTTATTGATGGATACTCAGGGAACCTTTGATAGTCAGTCAACTTTGAGAGATTCA
  GCCACAGTATTTGCCCTTAGCACAATGATCAGCTCAATACAGGTATATAACTTATCCCAA
  AATGTCCAGGAGGATGATCTTCAGCACCTCCAGCTTTTCACTGAGTATGGCAGACTGGCA
  ATGGAGGAAACATTCCTGAAGCCATTTCAGAGTCTGATATTTCTTGTTCGAGACTGGAGT
  TTCCCATACGAATTTTCATATGGAGCCGATGGTGGTGCCAAATTCTTGGAAAAACGCCTC
  AAGGTCTCAGGGAACCAGCATGAAGAACTACAGAACGTCAGAAAACACATCCATTCCTGT
  TTCACCAACATTTCCTGTTTTCTGCTACCTCATCCTGGCTTAAAAGTAGCTACCAATCCA
  AACTTTGATGGAAAATTGAAAGAAATAGATGATGAATTCATCAAAAACTTGAAAATACTG
  ATTCCTTGGCTACTTAGTCCCGAGAGCCTAGATATTAAAGAGATCAATGGGAATAAAATC
  ACCTGCCGGGGTCTGGTGGAGTACTTCAAGGCTTATATAAAGATCTATCAAGGTGAAGAA
  TTACCACATCCCAAATCCATGTTACAGGCCACAGCAGAAGCTAACAATTTAGCAGCCGTG
  GCAACTGCCAAGGACACATACAACAAAAAAATGGAAGAGATTTGTGGTGGTGACAAACCA
  TTTCTGGCCCCAAATGACTTGCAGACCAAACACCTGCAACTTAAGGAAGAATCTGTGAAG
  CTATTCCGAGGGGTGAAGAAGATGGGTGGGGAAGAATTTAGCCGGCGTTACCTGCAGCAG
  TTGGAGAGTGAAATAGATGAACTTTACATCCAATATATCAAGCACAATGATAGCAAAAAT
  ATCTTCCATGCAGCTCGTACCCCAGCCACACTGTTTGTAGTCATCTTTATCACATATGTG
  ATTGCTGGTGTGACTGGATTCATTGGTTTGGACATCATAGCTAGCCTATGCAATATGATA
  ATGGGACTGACCCTTATCACCCTGTGCACTTGGGCATATATCCGGTACTCTGGAGAATAC
  CGAGAGCTGGGAGCTGTAATAGACCAGGTGGCTGCAGCTCTGTGGGACCAGGGAAGTACA
  AATGAGGCTTTGTACAAGCTTTACAGTGCAGCAGCAACCCACAGACATCTGTATCATCAA
  GCTTTCCCTACACCAAAGTCGGAATCTACTGAACAATCAGAAAAGAAAAAAATGTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015915 unedited
  ATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGCGCCCAGCGCGGGCA
  CGGAGCCTCCCACCGCCAGCAACCTGCGGCCCCGGAGAAGGCAGCGAGCGCAGTGACAGC
  GCCTCACCGCCACCAGCTCCTGGACCACCATGGCCAAGAACCGCAGGGACAGAAACAGTT
  GGGGTGGATTTTCGGAAAAGACATATGAATGGAGCTCAGAAGAGGAGGAGCCAGTGAAAA
  AGGCAGGACCAGTCCAAGTCCTCATTGTCAAAGATGACCATTCCTTTGAGTTAGATGAAA
  CTGCATTAAATCGGATCCTTCTCTCGGAGGCTGTCAGAGACAAGGAGGTTGTTGCTGTAT
  CTGTTGCTGGAGCATTTAGAAAAGGAAAATCATTCCTGATGGACTTCATGTTGAGATACA
  TGTACAACCAGGAATCAGTTGATTGGGTTGGAGACTACAATGAACCATTGACTGGTTTTT
  CATGGAGAGGTGGATCTGAACGAGAGACCACAGGAATTCAGATATGGAGTGAAATCTTCC
  TTATCAATAAACCTGATGGTAAAAAGGTTGCAGTGTTATTGATGGATACTCAGGGAACCT
  TTGATAGTCAGTCAACTTTGAGAGATTCAGCCACAGTATTTGCCCTTAGCACAATGATCA
  GCTCAATACAGGTATATAACTTATCCCANATGTCCAGGAGGATGATCTTCAGCACCTCCA
  GCTTTTCACTGAGTATGGCAGACTGGNCATGGAGGAAACATTCCTGAAGCCATTTCAGAG
  TCTGATATTTCTTGGTCGAGACTGGAGTTNNCCCATACGAATTTCATATGGAGCCGATGG
  TGGTGCCCAAATCTTGGAAAACGCTCAGGTCTCAGGAACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015915 unedited
  NTTTTAGCTCTGNACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTATC
  ATAAATAGACAAATACTTTATAACAGCATTTTTGAAGAAAAATCAGGAAATTGTACATGT
  TAACAAAATAGTATAACCATGCATACATACATCTGCTTATTAAACACTGAAGTAAAAGAA
  CTAATCCAGTTTGCAGTCTTCAGAGGTGTTTAGTATTTTACTCCGTTCTGATGGAAGCAC
  TTTGAATGTTTGCATGGAGACATAAAACTGAATATTTAATTGACAATTGGTCATGCACCT
  GTATTTCTTAAAATTTGCATTACATTTTTTTCTTTTCTGATTGTTCAGTAGATTCCGACT
  TTGGTGTAGGGAAAGCTTGATGATACAGATGTCTGTGGGTTGCTGCTGCACTGTAAAGCT
  TGTACAAAGCCTCATTTGTACTTCCCTGGTCCCACAGAGCTGCAGCCACCTGGTCTATTA
  CAGCTCCCAGCTCTCGGTATTCTCCAGAGTACCGGATATATGCCCAAGTGCACAGGGTGA
  TAAGGGTCAGTCCCATCATCATACTGCCTAGGCTAGCTATGATGTCCAAACCCATGAATT
  CAGTCACACCAGCACTTACATATGTGATCAAGATGACTCCAAACAGTGTGGCTGGGGTAC
  GAGCTGCCTGAAAGAATTTTCTGCTATCATTGCGCCTGATATATTGGATGCAAAGCTCAT
  CTATTTCACTCTCCAACTGCTGGAGGTAACGCCCGGTTAATTTTTTCCCACCCATCTTCT
  TCACCCCTCGAATACCTTATAGATTCTTCCTTAATTGCCAGTGCTTGGTCTGCAACTCAT
  CCGGTGCCACAAAGGGCTGGCACCCCACAAATCTTCCCCTTTTTCGGTGGATGGCTCCCG
  CN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015915
• ORF Size: 1677 bp
• Insert Size: 630
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015915.3, NP_056999.2
• RefSeq Size: 2271
• RefSeq ORF: 1677
• Locus ID: 51062
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (a).