Mitofusin 2 (MFN2) (NM_014874) Human Untagged Clone

CAT#: SC114726

MFN2 (untagged)-Human mitofusin 2 (MFN2), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MFN2
• Synonyms: CMT2A; CMT2A2; CMT2A2A; CMT2A2B; CPRP1; HMSN6A; HSG; MARF
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014874, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCCCTGCTCTTCTCTCGATGCAACTCTATCGTCACAGTCAAGAAAAATAAGAGACACATGGCTGAGG
  TGAATGCATCCCCACTTAAGCACTTTGTCACTGCCAAGAAGAAGATCAATGGCATTTTTGAGCAGCTGGG
  GGCCTACATCCAGGAGAGCGCCACCTTCCTTGAAGACACGTACAGGAATGCAGAACTGGACCCCGTTACC
  ACAGAAGAACAGGTTCTGGACGTCAAAGGTTACCTATCCAAAGTGAGAGGCATCAGTGAGGTGCTGGCTC
  GGAGGCACATGAAAGTGGCTTTTTTTGGCCGGACGAGCAATGGGAAGAGCACCGTGATCAATGCCATGCT
  CTGGGACAAAGTTCTGCCCTCTGGGATTGGCCACACCACCAATTGCTTCCTGCGGGTAGAGGGCACAGAT
  GGCCATGAGGCCTTTCTCCTTACCGAGGGCTCAGAGGAAAAGAGGAGTGCCAAGACTGTGAACCAGCTGG
  CCCATGCCCTCCACCAGGACAAGCAGCTCCATGCCGGCAGCCTAGTGAGTGTGATGTGGCCCAACTCTAA
  GTGCCCACTTCTGAAGGATGACCTCGTTTTGATGGACAGCCCTGGTATTGATGTCACCACAGAGCTGGAC
  AGCTGGATTGACAAGTTTTGTCTGGATGCTGATGTGTTTGTGCTGGTGGCCAACTCAGAGTCCACCCTGA
  TGCAGACGGAAAAGCACTTCTTCCACAAGGTGAGTGAGCGTCTCTCCCGGCCAAACATCTTCATCCTGAA
  CAACCGCTGGGATGCATCTGCCTCAGAGCCCGAGTACATGGAGGAGGTGCGGCGGCAGCACATGGAGCGT
  TGTACCAGCTTCCTGGTGGATGAGCTGGGCGTGGTGGATCGATCCCAGGCCGGGGACCGCATCTTCTTTG
  TGTCTGCTAAGGAGGTGCTCAACGCCAGGATTCAGAAAGCCCAGGGCATGCCTGAAGGAGGGGGCGCTCT
  CGCAGAAGGCTTTCAAGTGAGGATGTTTGAGTTTCAGAATTTTGAGAGGAGATTTGAGGAGTGCATCTCC
  CAGTCTGCAGTGAAGACCAAGTTTGAGCAGCACACGGTCCGGGCCAAGCAGATTGCAGAGGCGGTTCGAC
  TCATCATGGACTCCCTGCACATGGCGGCTCGGGAGCAGCAGGTTTACTGCGAGGAAATGCGTGAAGAGCG
  GCAAGACCGACTGAAATTTATTGACAAACAGCTGGAGCTCTTGGCTCAAGACTATAAGCTGCGAATTAAG
  CAGATTACGGAGGAAGTGGAGAGGCAGGTGTCGACTGCAATGGCCGAGGAGATCAGGCGCCTCTCTGTAC
  TGGTGGACGATTACCAGATGGACTTCCACCCTTCTCCAGTAGTCCTCAAGGTTTATAAGAATGAGCTGCA
  CCGCCACATAGAGGAAGGACTGGGTCGAAACATGTCTGACCGCTGCTCCACGGCCATCACCAACTCCCTG
  CAGACCATGCAGCAGGACATGATAGATGGCTTGAAACCCCTCCTTCCTGTGTCTGTGCGGAGTCAGATAG
  ACATGCTGGTCCCACGCCAGTGCTTCTCCCTCAACTATGACCTAAACTGTGACAAGCTGTGTGCTGACTT
  CCAGGAAGACATTGAGTTCCATTTCTCTCTCGGATGGACCATGCTGGTGAATAGGTTCCTGGGCCCCAAG
  AACAGCCGTCGGGCCTTGATGGGCTACAATGACCAGGTCCAGCGTCCCATCCCTCTGACGCCAGCCAACC
  CCAGCATGCCCCCACTGCCACAGGGCTCGCTCACCCAGGAGGAGTTCATGGTTTCCATGGTTACCGGCCT
  GGCCTCCTTGACATCCAGGACCTCCATGGGCATTCTTGTTGTTGGAGGAGTGGTGTGGAAGGCAGTGGGC
  TGGCGGCTCATTGCCCTCTCCTTTGGGCTCTATGGCCTCCTCTACGTCTATGAGCGTCTGACCTGGACCA
  CCAAGGCCAAGGAGAGGGCCTTCAAGCGCCAGTTTGTGGAGCATGCCAGCGAGAAGCTGCAGCTTGTCAT
  CAGCTACACTGGCTCCAACTGCAGCCACCAAGTCCAGCAGGAACTGTCTGGGACCTTTGCTCATCTGTGT
  CAGCAAGTTGACGTCACCCGGGAGAACCTGGAGCAGGAAATTGCCGCCATGAACAAGAAAATTGAGGTTC
  TTGACTCACTTCAGAGCAAAGCAAAGCTGCTCAGGAATAAAGCCGGTTGGTTGGACAGTGAGCTCAACAT
  GTTCACACACCAGTACCTGCAGCCCAGCAGATAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014874 unedited
  NGGTTCGAATTTTGGTATACGAACTCACTATAGGGCGGCCGCGATTCGGCACCAGGGGAG
  GTGAAGTCAGGACTGGTGGAGTCAACACAGTCAATCAATAGCCAACCTCAACCTGAGACA
  GGACAGAAGAGAACTCAGAATCTTTTTGTCTTTTGGACTTCAGCCATGTCCATGATGCCT
  ACCCTGTGAAGATCTCTCACCATCCAAAAAACGCAATGTCCCTGCTCTTCTCTCGATGCA
  ACTCTATCGTCACAGTCAAGAAAAATAAGAGACACATGGCTGAGGTGAATGCATCCCCAC
  TTAAGCACTTTGTCACTGCCAAGAAGAAGATCAATGGCATTTTTGAGCAGCTGGGGGCCT
  ACATCCAGGAGAGCGCCACCTTCCTTGAAGACACGTACAGGAATGCAGAACTGGACCCCG
  TTACCACAGAAGAACAGGTTCTGGACGTCAAAGGTTACCTATCCAAAGTGAGAGGCATCA
  GTGAGGTGCTGGCTCGGAGGCACATGAAAGTGGCTTTTTTTGGCCGGACGAGCAATGGGA
  AGAGCACCGTGATCAATGCCATGCTCTGGGACAAAGTTCTGCCCTCTGGGATTGGCCACA
  CCACCAATTGCTTCCTGCGGGTAGAGGGCACAGATGGCCATGAGGCCTTTCTCCTTACCG
  AGGGCTCAGAGGAAAAGAGGAGTGCCAAGACTGTGAACCAGCTGGCCCATGCCCTCCACC
  AGGACAAGCAGCTCCATGCCGGCAGCCTAGTGAGTGTGATGTGGCCCAACTCTAAGTGCC
  CACTTCTGAAGGATGACCTCGTTTTGATGGACAGNCCCTGGTATTGATGTCACCACAGAG
  CTGGACAGCTGGATTGACAAGTNTTGTCTGATGCTGATGNGTTTGTGCTGGTGGCCACTC
  AGAGTCANCCCTGAGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014874 unedited
  CTATGGACCCGCGGCCGCAATCTAGNAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCACCAAGAGGATTCCCACCTGGGTTTTTTT
  TTATTTCCCAATTTTTGGACCATGGATCCGGGGGTACCTCAGCCAAATCCTTCCCCTTAA
  ATCCTTCAAAAAAACCTCCTTGGGTCACCCCGTTTGGCCCCCCACCAAAGGACCTTAAAA
  CCACCATGGCCCCCACCTTAAAAGGGCTTTGGGCCATCCTTTTTTAAAAAGGGGCCTCCC
  CCTCAGGGGAAAAAATTAAATTTTCCGTTTGGAAAAACCCCAAAATTTTTTTCTTTCCCC
  GGGGGCTCCTTTAAAAAAAAATTCTTGTTCCCCCTAAAAAATTTTTTTTTTTCAAAAAAA
  CCCCAAATTCCTTGGAAATGGGGGAACAGGAATTTCCCCTAACATGCTGGAAAGGGGCCC
  TGGTCCTTTAGGGCCCCCCACCCCCCGGGACACCCCCCCCCCACCTTGCCCCCCGGCAAG
  ACTCCCACCCTTCCCCCCCAACCCAAGGCCACACGGGGGGCTCTTAACCCCCCGCGTTTC
  CCCCAACGGCCCACCACCCTGATTGCGGCGGCTCCCACATGGCGTGAGGGGGCGTTCCCA
  TCCCCCCCTCAACCAGCCCATCCGGCGCCTGGCCCNCCCCCCCCCCACACAGCGGCGCCC
  CCTTTCTGACCGATGCCATCTTCNCGCACCGTCACGCACTTACGCGTACACTGTCTCTAT
  CATCATTATTTTCATACGCATTCCTNGACCAATCCTCCCCNTTTCCCCCCCCGCTTCTCC
  GGCCCGCCACCTCTGTTTCCCCCCACGCGCCACCCGTATATTTACACCCCCGCACCCCCC
  ACGCGTTCCTCTCTCCCCNNNNCNACCCTACCTCCCCGCCGCCTCCGCCCCCCATTTGGC
  CCCGCACCACCCTCACTTACTNTCTCCACTTACTCACCCCCGTACAACCCACTCTCCCCA
  CTCCCCCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014874
• ORF Size: 2274 bp
• Insert Size: 3810
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014874.2, NP_055689.1
• RefSeq Size: 4546
• RefSeq ORF: 2274
• Locus ID: 9927
• Domains: fzo_mitofusin
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.