CDC42 binding protein kinase alpha (CDC42BPA) (NM_014826) Human Untagged Clone

CAT#: SC114791

CDC42BPA (untagged)-Human CDC42 binding protein kinase alpha (DMPK-like) (CDC42BPA), transcript variant A


  "NM_014826" in other vectors (5)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CDC42BPA
Synonyms MRCK; MRCKA; PK428
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_014826 edited
CAGCAAGATTTAGAAATAAAAAACTTAAAAGAAGAAATTGAAAAACTAAGAAAACAAGTA
ACAGAATCAAGTCATTTGGAACAGCAACTTGAAGAAGCTAATGCTGTGAGGCAAGAACTA
GATGATGCTTTTAGACAAATCAAGGCTTATGAAAAACAAATCAAAACGTTACAACAAGAA
AGAGAAGATCTAAATAAGCTGGAAGTTCATACAGAAGCTCTAGCTGCTGAAGCATCTAAA
GACAGGAAGCTACGTGAACAGAGTGAGCACTATTCTAAGCAACTGGAAAATGAATTGGAG
GGACTGAAGCAAAAACAAATTAGTTACTCACCAGGAGTATGCAGCATAGAACATCAGCAA
GAGATAACCAAACTAAAGACTGATTTGGAAAAGAAAAGTATCTTTTATGAAGAAGAATTA
TCTAAAAGAGAAGGAATACATGCAAATGAAATAAAAAATCTTAAGAAAGAACTGCATGAT
TCAGAAGGTCAGCAACTTGCTCTCAACAAAGAAATTATGATTTTAAAAGACAAATTGGAA
AAAACCAGAAGAGAAAGTCAAAGTGAAAGGGAGGAATTTGAAAGTGAGTTCAAACAACAA
TATGAACGAGAAAAAGTGTTGTTAACTGAAGAAAATAAAAAGCTGACGAGTGAACTTGAT
AAGCTTACTACTTTGTATGAGAACTTAAGTATACACAACCAGCAGTTAGAAGAAGAGGTT
AAAGATCTAGCAGACAAGAAAGAATCAGTTGCACATTGGGAAGCCCAAATCACAGAAATA
ATTCAGTGGGTCAGCGATGAAAAGGATGCACGAGGGTATCTTCAGGCCTTAGCTTCTAAA
ATGACTGAAGAATTGGAGGCATTAAGAAATTCCAGCTTGGGTACACGAGCAACAGATATG
CCCTGGAAAATGCGTCGTTTTGCGAAACTGGATATGTCAGCTAGACTGGAGTTGCAGTCG
GCTCTGGATGCAGAAATAAGAGCCAAACAGGCCATCCAAGAAGAGTTGAATAAAGTTAAA
GCATCTAATATCATAACAGAATGTAAACTAAAAGATTCAGAGAAGAAGAACTTGGAACTA
CTCTCAGAAATCGAACAGCTGATAAAGGACACTGAAGAGCTTAGATCTGAAAAGGGTATA
GAGCACCAAGACTCACAGCATTCTTTCTTGGCATTTTTGAATACGCCTACCGATGCTCTG
GATCAATTTGAAACTGATCCCGTTGAGAACACATATGTATGGAACCCGAGCGTCAAGTTT
CACATCCAGTCACGGTCCACATCTCCTTCCACATCTAGTGAAGCTGAGCCAGTTAAGACT
GTAGACTCCACTCCACTTTCAGTTCACACACCAACCTTAAGGAAAAAAGGATGTCCTGGT
TCAACTGGCTTTCCACCTAAGCGCAAGACTCACCAGTTTTTTGTAAAATCTTTTACTACT
CCTACCAAGTGTCATCAGTGTACCTCCTTGATGGTGGGTTTAATAAGACAGGGCTGTTCA
TGTGAAGTGTGTGGATTCTCATGCCATATAACTTGTGTAAACAAAGCTCCAACCACTTGT
CCAGTTCCTCCTGAACAGACAAAAGGTCCCCTGGGTATAGATCCTCAGAAAGGAATAGGA
ACAGCATATGAAGGTCATGTCAGGATTCCTAAGCCAGCTGGAGTGAAGAAAGGGTGGCAG
AGAGCACTGGCTATAGTGTGTGACTTCAAACTCTTTCTGTACGATATTGCTGAAGGAAAA
GCATCTCAGCCCAGTGTTGTCATTAGTCAAGTGATTGACATGAGGGATGAAGAATTTTCT
GTGAGTTCAGTCTTGGCTTCTGATGTTATCCATGCAAGTCGGAAAGATATACCCTGTATA
TTTAGGGTCACAGCTTCCCAGCTCTCAGCATCTAATAACAAATGTTCAATCCTGATGCTA
GCAGACACTGAGAATGAGAAGAATAAGTGGGTGGGAGTGCTGAGTGAATTGCACAAGATT
TTGAAGAAAAACAAATTCAGAGACCGCTCAGTCTATGTTCCCAAAGAGGCTTATGACAGC
ACTCTACCCCTCATTAAAACAACCCAGGCAGCCGCAATCATAGATCATGAAAGAATTGCT
TTGGGAAACGAAGAAGGGTTATTTGTTGTACATGTCACCAAAGATGAAATTATTAGAGTT
GGTGACAATAAGAAGATTCATCAGATTGAACTCATTCCAAATGATCAGCTTGTTGCTGTG
ATCTCAGGACGAAATCGTCATGTACGACTTTTTCCTATGTCAGCATTGGATGGGCGAGAG
ACCGATTTTTACAAGCTGTCAGAAACTAAAGGGTGTCAAACCATAACTTCTGGAAAGGTG
CGCCATGGAGCTCTCACATGCCTGTGTGTGGCTATGAAAAGGCAGGTCCTCTGTTATGAA
CTATTTCAGAGCAAGACCCGTCACAGAAAATTTAAGGAAATTCAAGTCCCATATAATGTC
CAGTGGATGGCAATCTTCAGTGAACAACTCTGTGTGGGATTCCAGTCAGGATTTCTAAGA
TACCCCTTGAATGGAGAAGGAAATCCATACAGTATGCTCCATTCAAATGACCATACACTA
TCATTTATTGCACATCAACCAATGGATGCTATCTGCGCAGTTGAGATCTCCAGTAAAGAA
TATCTGCTGTGTTTTAACAGCATTGGGATATACACTGACTGCCAGGGCCGAAGATCTAGA
CAACAGGAATTGATGTGGCCAGCAAATCCTTCCTCTTGTTGTTACAATGCACCATATCTC
TCGGTGTACAGTGAAAATGCAGTTGATATCTTTGATGTGAACTCCATGGAATGGATTCAG
ACTCTTCCTCTCAAAAAGGTTCGACCCTTAAACAATGAAGGATCATTAAATCTTTTAGGG
TTGGAGACCATTAGATTAATATATTTCAAAAATAAGATGGCAGAAGGGGACGAACTGGTA
GTACCTGAAACATCAGATAATAGTCGGAAACAAATGGTTAGAAACATTAACAATAAGCGG
CGTTATTCCTTCAGAGTCCCAGAAGAGGAAAGGATGCAGCAGAGGAGGGAAATGCTACGA
GATCCAGAAATGAGAAATAAATTAATTTCTAATCCAACTAATTTTAATCACATAGCACAC
ATGGGTCCTGGAGATGGAATACAGATCCTGAAAGATCTGCCCATGAACCCTCGGCCTCAG
GAAAGTCGGACAGTATTCAGTGGCTCAGTCAGTATTCCATCTATCACCAAATCCCGCCCT
GAGCCAGGCCGCTCCATGAGTGCTAGCAGTGGCTTGTCAGCAAGGTCATCCGCACAGAAT
GGCAGCGCATTAAAGAGGGAATTCTCTGGAGGAAGCTACAGTGCCAAGCGGCAGCCCATG
CCCTCCCCGTCAGAGGGCTCTTTGTCCTCCGGAGGCATGGACCAAGGAAGTGATGCCCCA
GCGAGGGACTTTGACGGAGAGGACTCTGACTCTCCGAGGCATTCCACAGCTTCCAACAGT
TCCAACCTAAGCAGCCCCCCAAGCCCAGTTTCACCCCGAAAAACCAAGAGCCTCTCCCTG
GAGAGCACTGACCGCGGGAGCTGGGACCCGTGAGCTGCCTTAGCACTGGGACCTCTCGCT
CTCCGCTCCCTGCCACTCGCCTCCTCTCACTTTCATCTCTTCCCTCCACCTCGCCTGCTC
GGCCTGAAAGCCACCAGGGGCTGGCAGCAGTAGCAGGACAGGGATTCAGGAGTTCTGACG
ACACGACTCTCAGATCCACGCCCCCAGCCTAACAGCAACAACAAAGACAGACTTTCCGTA
GCAGCTTAGATTAACGTTGATTTCATTCCATGCACTTAGAGTTGCTTTCAGTAACATTTT
ACCCCTACTCCCAAAGGTAGCTTAAATAGACAGATTACACAAATGTAAGTGATAAGAATA
AGATTAGACAGATTTTGCTTTCACAGTAGAGTCTCATTATAGTCCTAAAATAGCTCATGG
GCTTCTCCGCATCCAGAAGGGAGAATTGGTCCCTGGAGTGGCTCACTAAGCTCTTAATCA
GCAAACGCAGTGAGTATCAACCTGATTGTTGCCAGGAAATCCTTATGAATTAAAACAATG
CATATTTTACTACAGTACAGAGTTTAAATGAATACATAAATGTAGAAGTACTGAATGTAT
ATATTTAAAAGGAGCCTCTTGTATTCAACAAAAGATGGATGCATATATAAGAGAGATGAT
TTAATTTAAAAAAAAAAAAAAAAAAAACTCGAC
>OriGene 5' read for NM_014826 unedited
NGGGTCANAATTTGTATACGACTCCTATAGGCCGGCCGCGAATTCGGCACGAGGGAAAAT
GAAGAGTTTTCACCGGAATCCGTTGAAAATAGACTGACTGCAAAGCCTTAAAGAAAGAAG
GACCTCGGGAGGAGAAACGAAAAGCCGCCTCCGGGCAAGACTTGGCGTGCTCCGAGCCGA
GGGGCTGCTTCAGGGACCTCGCCCCCTCCCTTTCCTGCTGGAGAAATTGCCGCTGATGCA
TTATCCAAGTGGTGGTTGGGAGGATTTGCAGCAACATTTTTGGTTTTCCCTCCCCCTTCT
ATGCATTCTGTTTTTTTCCTCCCTTTTCTGTTTTTCTTCTTCCCGGGAAGTGAATTGCTG
ATGCAAATCGGACTTTATTCATTAATGATGCAACCGGATTGCATCAGGATTACGTTGCAC
GAGTTGAATTTTGAATGAAGGAGAAGAGTTTTTTTTTTTTTAAAGAAGTGTTGACTCTCT
AGTTCGTTGTACTTTTAATTATTATTTTATTTAAATATACGACTTAATTGTATTCTTTTA
AAAATGCATTAAGTATATATTTTATGGTAATTTACCCTCAAAATATATGTATATGGGTGA
AATTGAAGACGCTTCAGTTAAGTGAGGTTACTGGTGTGTTGGATGTTTAATTCAGCACCA
GCATTGCATGACAGTTGTTTGAATAACAAGTGGTTTATTTTTAAAACCATACCTTTTAAA
ATTTAGGTTCAGATAATAGTAAAAGTCATCATAATAATTTAAAGGANAACCAGCAGAAAT
CGAAGCANACATGTCTGGAGAAGTGCGTTTGAGGCAGTTGGAGCAGTTTATTTTGGACGG
GCCCGCTCAGACCAATGGGCAGTGCTTCAGTGTGGAGACTTACTGGATATACTCATCTGC
CTTTATGATGA
>OriGene 3' read for NM_014826 unedited
NNAAATTCAGCTTGNACCGCGCGCCGTATNCTANGATCGAGTTTTTTTTTTTTTTTTTTT
TAAATTAAATCATCTCTCTTATATATGCATCCATCTTTTGTTGAATACAAGAGGCTCCTT
TTAAATATATACATTCAGTACTTCTACATTTATGTATTCATTTAAACTCTGTACTGTAGT
AAAATATGCATTGTTTTAATTCATAAGGATTTCCTGGCAACAATCAGGTTGATACTCACT
GCGTTTGCTGATTAAGAGCTTAGTGAGCCACTCCAGGGACCAATTCTCCCTTCTGGATGC
GGAGAAGCCCATGAGCTATTTTAGGACTATAATGAGACTCTACTGTGAAAGCAAAATCTG
TCTAATCTTATTCTTATCACTTACATTTGTGTAATCTGTCTATTTAAGCTACCTTTGGGA
GTAGGGGTAAAATGTTACTGAAAGCAACTCTAAGTGCATGGAATGAAATCAACGTTAATC
TAAGCTGCTACGGAAAGTCTGTCTTTGTTGTTGCTGTTAGGCTGGGGGCGTGGATCTGAG
AGTCGTGTCGTCAGAACTCCTGAATCCCTGTCCTGCTACTGCTGCCAGCCCCTGGTGGCT
TTCAGGCCGAGCAGGCGAGGTGGAGGGAAGAGATGAAAGTGAGAGGAGGCGAGTGGCAGG
GAGCGGAGAGCGAGAGGTCCCAGTGCTAAGGCAGCTCACGGGTCCCAGCTCCCGCGGTCA
GTGCTCTCCAGGGAGAGGCTCTTGGTTTTTCGGGGTGAAACTGGGCTTTGGGGGCTGCTT
AAGTTGGAACTGTTGGAAGCTGTGGAATGCCTGGGAGAATAAAAGTCCTCTCCGTCAAGT
CCCTCGCTTGGGCATCATTCCTGGACCCATGCTCCGAAGAAAAAG
Restriction Sites NotI-NotI     
ACCN NM_014826
ORF Size 4917 bp
Insert Size 6200
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_014826.3, NP_055641.3
RefSeq Size 7776
RefSeq ORF 4917
Locus ID 8476
Protein Families Druggable Genome, Protein Kinase
Gene Summary The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018]
Transcript Variant: This variant (A) lacks a coding segment compared to variant B, resulting in an isoform (A) that lacks an internal region, as compared to isoform B.

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