EIF4A3 (NM_014740) Human Untagged Clone

CAT#: SC114843

EIF4A3 (untagged)-Human eukaryotic translation initiation factor 4A3 (EIF4A3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EIF4A3
• Synonyms: DDX48; eIF-4A-III; eIF4A-III; eIF4AIII; Fal1; MUK34; NMP265; NUK34; RCPS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114843 sequence for NM_014740 edited (data generated by NextGen Sequencing)
  ATGGCGACCACGGCCACGATGGCGACCTCGGGCTCGGCGCGAAAGCGGCTGCTCAAAGAG
  GAAGACATGACTAAAGTGGAATTCGAGACCAGCGAGGAGGTGGATGTGACCCCCACGTTC
  GACACCATGGGCCTGCGGGAGGACCTGCTGCGGGGCATCTACGCTTACGGTTTTGAAAAA
  CCATCAGCAATCCAGCAACGAGCAATCAAGCAGATCATCAAAGGGAGAGATGTCATCGCA
  CAGTCTCAGTCCGGCACAGGAAAAACAGCCACCTTCAGTATCTCAGTCCTCCAGTGTTTG
  GATATTCAGGTTCGTGAAACTCAAGCTTTGATCTTGGCTCCCACAAGAGAGTTGGCTGTG
  CAGATCCAGAAGGGGCTGCTTGCTCTCGGTGACTACATGAATGTCCAGTGCCATGCCTGC
  ATTGGAGGCACCAATGTTGGCGAGGACATCAGGAAGCTGGATTACGGACAGCATGTTGTC
  GCGGGCACTCCAGGGCGTGTTTTTGATATGATTCGTCGCAGAAGCCTAAGGACACGTGCT
  ATCAAAATGTTGGTTTTGGATGAAGCTGATGAAATGTTGAATAAAGGTTTCAAAGAGCAG
  ATTTACGATGTATACAGGTACCTGCCTCCAGCCACACAGGTGGTTCTCATCAGTGCCACG
  CTGCCACACGAGATTCTGGAGATGACCAACAAGTTCATGACCGACCCAATCCGCATCTTG
  GTGAAACGTGATGAATTGACTCTGGAAGGCATCAAGCAATTTTTCGTGGCAGTGGAGAGG
  GAAGAGTGGAAATTTGACACTCTGTGTGACCTCTACGACACACTGACCATCACTCAGGCG
  GTCATCTTCTGCAACACCAAAAGAAAGGTGGACTGGCTGACGGAGAAAATGAGGGAAGCC
  AACTTCACTGTATCCTCAATGCATGGAGACATGCCCCAGAAAGAGCGGGAGTCCATCATG
  AAGGAGTTCCGGTCGGGCGCCAGCCGAGTGCTTATTTCTACAGATGTCTGGGCCAGGGGG
  TTGGATGTCCCTCAGGTGTCCCTCATCATTAACTATGATCTCCCTAATAACAGAGAATTG
  TACATACACAGAATTGGGAGATCAGGTCGATACGGCCGGAAGGGTGTGGCCATTAACTTT
  GTAAAGAATGACGACATCCGCATCCTCAGAGATATCGAGCAGTACTATTCCACTCAGATT
  GATGAGATGCCGATGAACGTTGCTGATCTTATCTGA
  
  Clone variation with respect to NM_014740.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014740 unedited
  GTTACCATTTGTATACGACTCACTATAGGCGGCCCGCGAATTCGCACGAGGCACAGCGAG
  GTCGGCAGCGGCACAGCGAGGTCGGCAGCGGCACAGCGAGGTCGGCAGCGGCAGCGAGGT
  CGGCAGCGGCGCGCGCTGTGCTCTTCCGCGGACTCTGAATCATGGCGACCACGGCCACGA
  TGGCGACCTCGGGCTCGGCGCGAAAGCGGCTGCTCAAAGAGGAAGACATGACTAAAGTGG
  GATTCGAGACCAGCGAGGAGGTGGATGTGACCCCCACGTTCGACACCATGGGCCTGCGGG
  AGGACCTGCTGCGGGGCATCTACGCTTACGGTTTTGAAAAACCATCAGCAATCCAGCAAC
  GAGCAATCAAGCAGATCATCAAAGGGAGAGATGTCATCGCACAGTCTCAGTCCGGCACAG
  GAAAAACAGCCACCTTCAGTATCTCAGTCCTCCAGTGTTTGGATATTCAGGTTCGTGAAA
  CTCAAGCTTTGATCTTGGCTCCCACAAGAGAGTTGGCTGTGCAGATCCAGAAGGGGCTGC
  TTGCTCTCGGTGACTACATGAATGTCCAGTGCCATGCCTGCATTGGAGGCACCAATGTTG
  GCGAGGACATCAGGAAGCTGGATTACGGACAGCATGTTGTCGCGGGCACTCCAGGGCGTG
  TTTTTGATATGATTCGTCGCAGAAGCCTAAGGACACGTGCTATCAAAATGTTGGTTTTGG
  ATGAAGCTGATGAAACGCTGAATAAAGGTTTCAAAGAGCAGATTTACGATGTATACAGGT
  ACCTGCCTTCAGCCACACAGGTGGTTCTCATCAGTGGCACGCTGGCACACCAGATTCTGG
  AGATGACCAACAAGTTCATGACCGACCCCATCCGCATTTTGGTGAAAACGGGATGAATTG
  ACCTCTGGAAGTCTCCAGCCAATTTTTCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014740 unedited
  GACCGCGGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGGGAAAAGTTTTAAA
  TTTTTAATGAAAAAGACTTAGAACAATGTATTATTTACATGTAAATAAGAAAAGAGAGCA
  GAATCCCCATATCCTCTTCAAAGGAAGGGAGACGGCAGGCCATTTATGAGAAGAAAGTCC
  ATATAAACCCCATTAAGTAGAATCTGGATCTAAATACTTCCAAACAGGAGTACACAGCAG
  GTGAACAGTCTCCCTCATCCCACTGATCTGCTGCTTCAGATAAGATCAGCAACGTTCATC
  GGCATCTCATCAATCTGAGTGGAATAGTACTGCTCGATATCTCTGAGGATGCGGATGTCG
  TCATTCTTTACAAAGTTAATGGCCACACCCTTCCGGCCGTATCGACCTGATCTCCCAATT
  CTGTGTATGTACAATTCTCTGTTATTAGGGAGATCATAGTTAATGATGAGGGACACCTGA
  GGGACATCCAACCCCCTGGCCCAGACATCTGTAGAAATAAGCACTCGGCTGGCGCCCGAC
  CGGAACTCCTTCATGATGGACTCCCGCTCTTTCTGGGGCATGTCTCCATGCATTGAGGAT
  ACAGTGAAGTTGGGCTTCCCTCATTTTCTCCGTCAGCCAGTCCACCTTTCTTTTGGTGTT
  GCANAAGATGACCGCCTGAGTGATGGGCAGTGTGTCGTACAGGGCACACAGAGTGTCAAA
  TTTTCACCTCTTCCTTTTCACTGCCACGAAAAATTGCTTGATGCCTCCAGAGTCATTCAT
  CACGTTTCACCCAGAGCCGGATTGGGTCGGCATGACCTTGTTGGTATCTCCAGAATTCGG
  GGGGACCGTGCCCTGAGAAAACCCCTGGGGGGTGGAGCAGGCCTGATACATGGAAACGGT
  TTTGAACCTTTTCAATTTATCACT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014740
• ORF Size: 1236 bp
• Insert Size: 1740
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014740.2, NP_055555.1
• RefSeq Size: 1702
• RefSeq ORF: 1236
• Locus ID: 9775
• Domains: DEAD, helicase_C
• Protein Families: Druggable Genome
• Protein Pathways: Spliceosome
• Gene Summary: This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. [provided by RefSeq, Jul 2008]