HERC3 (NM_014606) Human Untagged Clone

CAT#: SC114951

HERC3 (untagged)-Human hect domain and RLD 3 (HERC3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HERC3
• Synonyms: KIAA0032
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114951 sequence for NM_014606 edited (data generated by NextGen Sequencing)
  ATGTTATGTTGGGGATATTGGTCTCTGGGCCAACCTGGTATCAGCACCAACCTGCAGGGA
  ATTGTGGCTGAGCCCCAGGTGTGTGGGTTCATATCTGACAGAAGTGTCAAGGAAGTGGCC
  TGTGGGGGAAACCACTCTGTGTTCCTGCTGGAAGATGGGGAAGTTTACACATGTGGTTTG
  AACACCAAGGGGCAACTGGGCCATGAGAGGGAAGGAAACAAGCCAGAACAAATTGGAGCT
  CTGGCAGATCAGCATATCATTCATGTGGCATGTGGCGAGTCCCACAGTCTGGCCCTCAGT
  GACCGAGGCCAGCTGTTTTCTTGGGGTGCAGGGAGTGATGGTCAGCTAGGACTCATGACT
  ACTGAGGATTCTGTGGCAGTGCCCAGGTTAATACAAAAGCTGAACCAGCAAACAATATTA
  CAAGTTTCCTGTGGCAACTGGCATTGCTTGGCTCTTGCGGCTGATGGCCAGTTCTTCACC
  TGGGGAAAGAACAGCCATGGGCAGCTTGGCTTAGGGAAGGAGTTCCCCTCCCAAGCCAGC
  CCACAGAGGGTGAGGTCCCTGGAGGGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCT
  CACAGCTTTGCCCTGTCTCTCTCAGGAGCTGTTTTTGGCTGGGGGATGAATAATGCCGGG
  CAGCTAGGGCTCAGTGATGAAAAAGATCGAGAATCTCCATGCCATGTAAAACTCTTACGC
  ACGCAAAAAGTTGTCTATATTAGTTGTGGAGAAGAACACACAGCAGTTCTCACAAAGAGT
  GGAGGTGTGTTTACCTTTGGCGCTGGTTCCTGTGGGCAACTTGGACACGACTCCATGAAT
  GATGAGGTTAACCCTAGAAGAGTTCTAGAGCTGATGGGTAGTGAAGTAACTCAAATTGCT
  TGTGGCAGACAACATACCCTAGCCTTCGTGCCTTCTTCTGGACTCATCTATGCATTTGGT
  TGTGGAGCAAGAGGTCAATTAGGAACTGGGCACACTTGTAATGTTAAGTGCCCATCTCCT
  GTCAAGGGTTACTGGGCTGCCCACAGTGGCCAGCTTTCAGCCCGAGCTGATCGCTTTAAA
  TATCATATCGTTAAGCAGATCTTCTCTGGAGGAGACCAGACTTTTGTACTTTGCTCCAAA
  TACGAGAATTATTCTCCTGCTGTTGACTTCAGGACTATGAACCAAGCACATTATACCAGT
  TTAATAAATGATGAAACCATAGCAGTTTGGAGACAAAAACTCTCAGAACACAACAATGCA
  AATACAATCAATGGTGTTGTTCAGATATTATCTTCTGCAGCCTGTTGGAATGGAAGTTTT
  CTTGAAAAAAAAATTGATGAACATTTTAAAACGAGTCCCAAAATCCCTGGGATTGACCTG
  AACTCAACTAGGGTGTTATTTGAGAAGTTAATGAACTCTCAGCACTCCATGATTCTAGAA
  CAGATTTTGAACAGTTTTGAAAGTTGTCTGATTCCCCAGTTGTCAAGCTCACCACCAGAT
  GTTGAAGCCATGAGAATCTATTTAATACTACCTGAGTTTCCCCTACTCCAGGATTCCAAG
  TATTATATAACATTGACTATTCCCTTGGCTATGGCCATTCTTCGGCTGGATACAAACCCC
  AGCAAAGTACTAGATAACTGGTGGTCTCAGGTATGCCCGAAATATTTCATGAAGCTGGTA
  AACCTCTATAAAGGTGCAGTCCTTTATCTACTGAGGGGAAGAAAGACATTCTTAATTCCC
  GTACTGTTTAACAATTATATCACAGCAGCTCTCAAACTCTTGGAGAAGTTATATAAGGTA
  AATCTTAAAGTGAAGCATGTGGAATATGATACATTTTACATTCCTGAGATTTCCAATCTC
  GTGGACATTCAGGAAGACTACCTCATGTGGTTCTTGCATCAAGCAGGGATGAAGGCTAGA
  CCATCAATAATACAGGATACTGTAACACTTTGTTCCTACCCTTTCATCTTTGATGCCCAA
  GCCAAGACCAAAATGTTACAGACAGATGCTGAACTACAGATGCAGGTGGCAGTCAATGGA
  GCCAACCTGCAGAATGTCTTCATGCTTCTCACCCTGGAGCCTCTGCTGGCCAGAAGCCCC
  TTCCTGGTCCTTCACGTTCGCAGGAACAACCTTGTTGGAGATGCCCTAAGAGAGCTGAGC
  ATTCATTCTGATATTGATTTGAAAAAGCCTCTCAAAGTAATCTTTGATGGTGAAGAAGCA
  GTGGATGCCGGTGGTGTTACAAAGGAATTTTTTCTTTTGCTGTTAAAAGAACTTTTGAAT
  CCCATCTATGGAATGTTTACCTACTATCAAGATTCAAATCTCTTGTGGTTTTCAGACACG
  TGTTTTGTAGAGCACAACTGGTTTCACTTGATTGGTATAACCTGTGGACTAGCTATCTAC
  AACTCCACTGTGGTCGATCTCCACTTCCCATTGGCTCTCTACAAGAAGTTACTCAATGTA
  AAGCCTGGCTTGGAAGACTTAAAGGAGTTGTCACCCACTGAAGGAAGGAGTCTCCAAGAG
  CTTTTGGATTACCCCGGGGAGGATGTGGAGGAGACTTTCTGCCTCAACTTCACGATCTGC
  CGAGAAAGCTATGGAGTGATTGAACAGAAGAAGCTGATACCTGGGGGAGATAATGTAACT
  GTGTGCAAGGATAACAGGCAGGAATTTGTGGATGCTTATGTGAATTATGTCTTCCAAATC
  TCAGTTCATGAATGGTACACAGCCTTCTCTAGTGGCTTCCTAAAGGTGTGTGGTGGCAAA
  GTACTTGAGCTCTTCCAGCCTTCAGAACTGAGGGCTATGATGGTGGGGAACAGCAACTAC
  AACTGGGAAGAACTGCAAGAGACTGCCATCTACAAGGGAGATTACTCGGCCACACATCCC
  ACTGTAAAACTATTTTGGGAAACATTTCATGAGTTTCCATTGGAAAAGAAGAAGAAGTTT
  CTCTTGTTCCTGACAGGCAGCGATCGGATTCCCATCTACGGCATGGCCAGTCTGCAGATT
  GTCATCCAGTCCACAGCCAGCGGGGAGGAGTACTTGCCGGTGGCCCACACTTGCTACAAC
  CTTCTTGACCTCCCCAAGTACAGCAGCAAAGAGATTCTGAGTGCCCGGCTGACCCAGGCC
  CTTGACAACTATGAAGGGTTTAGTTTGGCCTGA
  
  Clone variation with respect to NM_014606.1
  2526 a=>g;2836 g=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014606 unedited
  GCATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACCAGGTCCGGCGAGA
  GGGGCTGTGACAGTCGGAGTCCCAAGCTGCGGTTCGGCTGCTGCCGAGAACTGCAAGGTG
  TGGAATATTTCTGGCTTCTAGTCCAATGCCAAGTGTGTGACCTGTGAGTTAATTCTGCAT
  TTTAGTTTTGGCCCTACATTTATTTAAAGCCTGAATTTGGGGAGTATCTGCAAAGCACTG
  AAGGTTTTGGACATTGTCTTTTCCTGCTGTTGAAAGAGACCCTCTTCATATATACAACAT
  TCAGGCTACATGATTCCCTGAAAGATAAGAACAATGTTATGTTGGGGATATTGGTCTCTG
  GGCCAACCTGGTATCAGCACCAACCTGCAGGGAATTGTGGCTGAGCCCCAGGTGTGTGGG
  TTCATATCTGACAGAAGTGTCAAGGAAGTGGCCTGTGGGGGAAACCACTCTGTGTTCCTG
  CTGGAAGATGGGGAAGTTTACACATGTGGTTTGAACACCAAGGGGCAACTGGGCCATGAG
  AGGGAAGGAAACAAGCCAGAACAAATTGGAGCTCTGGCAGATCAGCATATCATTCATGTG
  GCATGTGGCGAGTCCCACAGTCTGGCCCTCAGTGACCGAGGCCAGCTGTTTTCTTGGGGT
  GCAGGGAGTGATGGTCAGCTAGGACTCATGACTACTGAGGATTCTGTGGCAGTGCCCAGG
  TTAATACANAAAGCTGAACAGCANNACATATTACAAGTTTCCTGTGGCAACTGGCATTGC
  TTGGCTCTTGCNGCTGATGGCCAGNTCTTCACCTGGGGGAAGAACAGCCATGGGCAGCTT
  GGCTTAGGAAAGAGTTCCCCTCCCAGCCAGCCACAGAGGGTGAGGTCCCTGGAGGGGATC
  CACTGCCTCAGTGGCTGCCGGAGNGCTCACACTTTGCCTGCTCTTCAGAACTGTTTTGCT
  GGGGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014606 unedited
  TAGCTTTGNACNCGCGGCCGCATNCTAGNATCGAGTTTTTTTTTTTTTTTTTTTAAGTTA
  AAACACCAAATTTATTGCATAATATTGAACTATATGCACACACATAGNAAAATAAACATT
  TCATATAACTGTATATATATTTTTAATCCTGTATTTATAAAGACTGAAAAACTACCAATT
  TAGCAATTGGAATAAGTTTTAAAAACAAAAAGAAAAAGCAAAAATCTACAATCCTTCATC
  AAGATTTGATGCTTTATCACAGTTCATAAATACTTCATTTTATATAAATAAGTCTTTTCT
  CTAGTTACTAGGAATTTAAAATTAGACTTACATGGATTCTTTAATCATGTAGAATTTTCT
  TACTCCATGATGAGGAAGGTTGAGCATGTCATTATTTTTAAAATACATATATTTGATTTA
  AACACAATCCCCCCTAAAATCCCACTGTAAACAAACATTTCGAATGTGATAAAGTTTCAT
  AATAAAGAACGTCCTTAAATCTTAGCAATTAGGGAAGAGGAAAAAAAATCTGAGTAAAAA
  TTTTGCAATTTAAATAAAAATTGAAAAAAAGGCTGCATGCATCCACTAAAAGGAGAGGAG
  AGGAAGGGAGCACTGAGTCAAGTAACAGAGAATGGGATAAAATAAAGAAGAAACGAAAGG
  AAAATCAGGGAGGACGCAGGGTACGAAAAGGAGAAAATAAGGGAAGGGAGGAAGGAGAAA
  ATGGTAGAGGACATAAGGTGATAGAAAAAGGGAAAGNNAATTTATTATTTCTACTTTTCT
  TGGACATATAGAGACTCAAATAGTTATGGCACTTTGCTCAAAGCGAGAGTGCAGAGGTGT
  GGGTCTATCATTACCTTATGTAAGGNACAGGATGAGCAGAAAAATTAGCTCGCTGCACGA
  TGCTAGCTGTCTGCCATCTTTAAAGGTCTAGAATAGCCAGCATGGNAAAGTGCTATCCTC
  AGACTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014606
• ORF Size: 3153 bp
• Insert Size: 5270
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014606.1, NP_055421.1
• RefSeq Size: 4894
• RefSeq ORF: 3153
• Locus ID: 8916
• Domains: RCC1, HECT
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).