ADAM28 (NM_014265) Human Untagged Clone

CAT#: SC115083

ADAM28 (untagged)-Human ADAM metallopeptidase domain 28 (ADAM28), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADAM28
• Synonyms: ADAM 28; eMDC II; eMDCII; MDC-L; MDCL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_014265 edited
  GACACCGTGCTCCTGGAATCACCCAGCATGTTGCAAGGTCTCCTGCCAGTCAGTCTCCTC
  CTCTCTGTTGCAGTAAGTGCTATAAAAGAACTCCCTGGGGTGAAGAAGTATGAAGTGGTT
  TATCCTATAAGACTTCATCCACTGCATAAAAGAGAGGCCAAAGAGCCAGAGCAACAGGAA
  CAATTTGAAACTGAATTAAAGTATAAAATGACAATTAATGGAAAAATTGCAGTGCTTTAT
  TTGAAAAAAAACAAGAACCTCCTTGCACCAGGCTACACGGAAACATATTATAATTCCACT
  GGAAAGGAGATCACCACAAGCCCACAAATTATGGATGATTGTTATTATCAAGGACATATT
  CTTAATGAAAAGGTTTCTGACGCTAGCATCAGCACATGTAGGGGTCTAAGGGGCTACTTC
  AGTCAGGGGGATCAAAGATACTTTATTGAACCTTTAAGCCCCATACATCGGGATGGACAG
  GAGCATGCACTCTTCAAGTATAACCCTGATGAAAAGAATTATGACAGCACCTGTGGGATG
  GATGGTGTGTTGTGGGCCCACGATTTGCAGCAGAACATTGCCCTACCTGCCACCAAACTA
  GTAAAATTGAAAGACAGGAAGGTTCAGGAACATGAGAAATACATAGAATATTATTTGGTC
  CTGGATAATGGTGAGTTTAAAAGGTACAATGAGAATCAAGATGAGATCAGAAAGAGGGTA
  TTTGAGATGGCTAATTATGTCAACATGCTTTATAAAAAGCTCAATACTCATGTGGCCTTA
  GTTGGTATGGAAATCTGGACTGACAAGGATAAGATAAAGATAACCCCAAATGCAAGCTTC
  ACCTTGGAGAATTTTTCTAAATGGAGGGGGAGTGTTCTCTCAAGAAGAAAGCGTCATGAT
  ATTGCTCAGTTAATCACAGCAACAGAACTTGCTGGAACGACTGTGGGTCTTGCATTTATG
  TCTACAATGTGTTCTCCTTATTCTGTTGGCGTTGTTCAGGACCACAGCGATAATCTTCTT
  AGAGTTGCAGGGACAATGGCACATGAAATGGGCCACAACTTTGGAATGTTTCATGACGAC
  TATTCTTGCAAGTGTCCTTCTACAATATGTGTGATGGACAAAGCACTGAGCTTCTATATA
  CCCACAGACTTCAGTTCCTGCAGCCGTCTCAGCTATGACAAGTTTTTTGAAGATAAATTA
  TCAAATTGCCTCTTTAATGCTCCATTGCCTACAGATATCATATCCACTCCAATTTGTGGG
  AACCAGTTGGTGGAAATGGGAGAGGACTGTGATTGTGGGACATCTGAGGAATGTACCAAT
  ATTTGCTGTGATGCTAAGACATGTAAAATCAAAGCAACTTTTCAATGTGCATTAGGAGAA
  TGTTGTGAAAAATGCCAATTTAAAAAGGCTGGGATGGTGTGCAGACCAGCAAAAGATGAG
  TGCGACCTGCCTGAAATGTGTAATGGTAAATCTGGTAATTGTCCTGATGATAGATTCCAA
  GTCAATGGCTTCCCTTGCCATCACGGGAAGGGCCACTGCTTGATGGGGACATGCCCCACA
  CTGCAGGAGCAGTGCACAGAGCTGTGGGGACCAGGAACTGAGGTTGCAGATAAGTCATGT
  TACAACAGGAATGAAGGTGGGTCAAAGTACGGGTACTGTCGCAGAGTGGATGACACACTC
  ATTCCCTGCAAAGCAAATGATACCATGTGTGGGAAGTTGTTCTGTCAAGGTGGGTCGGAT
  AATTTGCCCTGGAAAGGACGGATAGTGACTTTCCTGACATGTAAAACATTTGATCCTGAA
  GACACAAGTCAAGAAATAGGCATGGTGGCCAATGGAACTAAGTGTGGCGATAACAAGGTT
  TGCATTAATGCAGAATGTGTGGATATTGAGAAAGCCTACAAATCAACCAATTGCTCATCT
  AAGTGCAAAGGACATGCTGTGTGTGACCATGAGCTCCAGTGTCAATGTGAGGAAGGATGG
  ATCCCTCCCGACTGCGATGACTCCTCAGTGGTCTTCCACTTCTCCATTGTGGTTGGGGTG
  CTGTTCCCAATGGCGGTCATTTTTGTGGTGGTTGCTATGGTAATCCGGCACCAGAGCTCC
  AGAGAAAAGCAGAAGAAAGATCAGAGGCCACTATCTACCACTGGCACCAGGCCACACAAA
  CAGAAGAGGAAACCCCAGATGGTAAAGGCTGTTCAACCCCAAGAGATGAGTCAGATGAAG
  CCCCATGTGTATGATCTGCCAGTAGAAGGCAATGAGCCCCCAGCCTCTTTTCATAAAGAC
  ACAAACGCACTTCCCCCTACTGTTTTCAAGGATAATCCAATGTCTACACCTAAGGACTCA
  AATCCAAAAGCATGAAGCAACAGCTAAGCAAGAACTAATGGCTAAATTATCAACTTGGAA
  AACTGGAAAATCTGGATGGCAGAGAAATATACTATCTCACCAGTATTTGCTCTCGACTCA
  AGAAGGTTAACATTTTCTGATTCATGTTAGACTTTGAAGAGACTAAAGAAAATTTTCAAG
  AGGAACATATGCCTGAGAACCTTTGCATGAATTTAAAATTTCAATTATCCATTCTTATAA
  GAAGGAAGATGATTGTAAAGAAATATCTCCGAAGTTAAAATCTGTAATAGGAATTGATTC
  ATTCTCTAATGAAAACAAAACATAAAAACATCACACTAATCTTGGAGGAATAAGAAAAAT
  TGTACATCCATTAAATGTACAATTGATTGCAACAAAAAAAAAAAAAAAAAACTCGAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014265 unedited
  CGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTTGCAATCAATTGTACATTTAATG
  GATGTACAATTTTTCTTATTCCTCCAAGATTAGTGTGATGTTTTTATGTTTTGTTTTCAT
  TAGAGAATGAATCAATTCCTATTACAGATTTTAACTTCGGAGATATTTCTTTACAATCAT
  CTTCCTTCTTATAAGAATGGATAATTGAAATTTTAAATTCATGCAAAGGTTCTCAGGCAT
  ATGTTCCTCTTGAAAATTTTCTTTAGTCTCTTCAAAGTCTAACATGAATCAGAAAATGTT
  AACCTTCTTGAGTCGAGAGCAAATACTGGTGAGATAGTATATTTCTCTGCCATCCAGATT
  TTCCAGTTTTCCAAGTTGATAATTTAGCCATTAGTTCTTGCTTAACTGCTGCTTCATGCT
  TTTGGATTTGAGTCCTTACGTGTAGACATTGGATTATCCTTGAAAACAGTAGGGGGAAGC
  GCGTTTGTGTCTTTATGAAAAGAGGCTGGGGGCTCATTGCCTTCTACTGGCAGATCATAC
  ACATGGGGCTTCATCTGACTCATCTCTTGGAGTTGAACAGCCTTTACCATCTGGGGTTTC
  CTCTTCTGTTTGTGTGGCCTGGCGCCAGTGGCAGATAGTGGCCTCTGATCTTTTTTCTGC
  TCTTCTCTGGAGCTCTGGTGCCGGATTCCATTTGCACCCCCACAAAATGACCCGCCTTGG
  GAACAGCACCCCACCCACATGGAAAATGGAAGACCACTGAGGATCATCGAGCCGGGAGGG
  ACCATCCTTCTTACATTGACCTTGAGCTCATGGCCCACCCAGATAGTCCTTGCCTTANAT
  GACAATTGGGTGATTGAGGCTCTCCATTCCCCCCTTTCGCTATGCAACCTTGTTTCCCCC
  TTATTCCTGGCCCCTGCCTATTTTGGCTGGGTTAGGAAAAAGTTTATGAGGAAAGACTTC
  GCCTTCACGAATTTCCCCCCCTGACAACC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014265
• ORF Size: 2328 bp
• Insert Size: 1500
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: no

Reference Data

• RefSeq: NM_014265.3, NP_055080.1
• RefSeq Size: 3181
• RefSeq ORF: 2328
• Locus ID: 10863
• Domains: Reprolysin, DISIN, Pep_M12B_propep, ACR
• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane
• Gene Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. This gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  Transcript Variant: This variant (1, also known as MDC-Lm) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.