ROC1 (RBX1) (NM_014248) Human Untagged Clone

CAT#: SC115112

RBX1 (untagged)-Human ring-box 1, E3 ubiquitin protein ligase (RBX1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RBX1
• Synonyms: BA554C12.1; RNF75; ROC1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_014248 edited
  AAATGGCGGCAGCGATGGATGTGGATACCCCGAGCGGCACCAACAGCGGCGCGGGCAAGA
  AGCGCTTTGAAGTGAAAAAGTGGAATGCAGTAGCCCTCTGGGCCTGGGATATTGTGGTTG
  ATAACTGTGCCATCTGCAGGAACCACATTATGGATCTTTGCATAGAATGTCAAGCTAACC
  AGGCGTCCGCTACTTCAGAAGAGTGTACTGTCGCATGGGGAGTCTGTAACCATGCTTTTC
  ACTTCCACTGCATCTCTCGCTGGCTCAAAACACGACAGGTGTGTCCATTGGACAACAGAG
  AGTGGGAATTCCAAAAGTATGGGCACTAGGAAAAGACTTCTTCCATCAAGCTTAATTGTT
  TTGTTATTCATTTAATGACTTTCCCTGCTGTTACCTAATTACAAATTGGATGGAACTGTG
  TTTTTTTCTGCTTTGTTTTTTCAGTTTGCTGTTTCTGTAGCCATATTGTATTCTGTGTCA
  AATAAAGTCCAGTTGGATTCTGAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014248 unedited
  GGGTTCACATTTGTATACTATCATATAGGGCGGCCGCGAATTCGCACCANAAAGGCGGCA
  GCGATGGATGTGGATACCCCGAGCGGCACCAACAGCGGCGCGGGCAAGAAGCGCTTTGAA
  GTGAAAAAGTGGAATGCAGTAGCCCTCTGGGCCTGGGATATTGTGGTTGATAACTGTGCC
  ATCTGCAGGAACCACATTATGGATCTTTGCATAGAATGTCAAGCTAACCAGGCGTCCGCT
  ACTTCAGAAGAGTGTACTGTCGCATGGGGAGTCTGTAACCATGCTTTTCACTTCCACTGC
  ATCTCTCGCTGGCTCAAAACACGACAGGTGTGTCCATTGGACAACAGAGAGTGGGAATTC
  CAAAAGTATGGGCACTAGGAAAAGACTTCTTCCATCAAGCTTAATTGTTTTGTTATTCAT
  TTAATGACTTTCCCTGCTGTTACCTAATTACAAATTGGATGGAACTGTGTTTTTTTCTGC
  TTTGTTTTTTCAGTTTGCTGTTTCTGTAGCCATATTGTATTCTGTGTCAAATAAAGTCCA
  GTTGGATTCTGAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCNGCCGCGGTCATAGC
  TGTTTTCCTGACAGATCCCGGGTGGCATCCCTGTGACCCCCTCCCAGTGCCTCTCCTGGC
  CCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAGTTGCATCATT
  TTGTCTGACTAGGTGTCCTTCTAAAAATTAATGGGGGTGAAGGGGGGTGGTATTGGAACA
  AGGGGGCAAGTTTGGAAAACAAAACCGGTAGGGCCTTGCGGGTGTCTATTGGGAACCCAG
  CCTGGGATGGCAGTGGCCCAAATCTTGGGTTCAATGGGATCTCCGCCCTCCCGGGTGTTA
  AGCAATTTTTCCTGGCCTCACCCTCTCCGAGTTGTTGGGAATTCCAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014248
• ORF Size: 327 bp
• Insert Size: 540
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_014248.2.

Reference Data

• RefSeq: NM_014248.2, NP_055063.1
• RefSeq Size: 521
• RefSeq ORF: 327
• Locus ID: 9978
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Nucleotide excision repair, Oocyte meiosis, Pathways in cancer, Renal cell carcinoma, TGF-beta signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway
• Gene Summary: This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5. [provided by RefSeq, Sep 2010]