TRPS1 (NM_014112) Human Untagged Clone

CAT#: SC115158

TRPS1 (untagged)-Human trichorhinophalangeal syndrome I (TRPS1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRPS1
• Synonyms: GC79; LGCR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115158 sequence for NM_014112 edited (data generated by NextGen Sequencing)
  ATGCCTTATGAAGTCAATGCTGGGTATGATTTTACAAATATGGTCCGGAAAAAGAACCCC
  CCTCTGAGAAACGTTGCAAGTGAAGGCGAGGGCCAGATCCTGGAGCCTATAGGTACAGAA
  AGCAAGGTATCTGGAAAGAACAAAGAATTTTCTGCAGATCAGATGTCAGAAAATACGGAT
  CAGAGTGATGCTGCAGAACTAAATCATAAGGAGGAACATAGCTTGCATGTTCAAGATCCA
  TCTTCTAGCAGTAAGAAGGACTTGAAAAGCGCAGTTCTGAGTGAGAAGGCTGGCTTCAAT
  TATGAAAGCCCCAGTAAGGGAGGAAACTTTCCCTCCTTTCCGCATGATGAGGTGACAGAC
  AGAAATATGTTGGCTTTCTCATCTCCAGCTGCTGGGGGAGTCTGTGAGCCCTTGAAGTCT
  CCGCAAAGAGCAGAGGCAGATGACCCTCAAGATATGGCCTGCACCCCCTCAGGGGACTCA
  CTGGAGACAAAGGAAGATCAGAAGATGTCACCAAAGGCTACAGAGGAAACAGGGCAAGCA
  CAGAGTGGTCAAGCCAATTGTCAAGGTTTGAGCCCAGTTTCAGTGGCCTCAAAAAACCCA
  CAAGTGCCTTCAGATGGGGGTGTAAGACTGAATAAATCCAAAACTGACTTACTGGTGAAT
  GACAACCCAGACCCGGCACCTCTGTCTCCAGAGCTTCAGGACTTTAAATGCAATATCTGT
  GGATATGGTTACTACGGCAACGACCCCACAGATCTGATTAAGCACTTCCGAAAGTATCAC
  TTAGGACTGCATAACCGCACCAGGCAAGATGCTGAGCTGGACAGCAAAATCTTGGCCCTT
  CATAACATGGTGCAGTTCAGCCATTCCAAAGACTTCCAGAAGGTCAACCGTTCTGTGTTT
  TCTGGTGTGCTGCAGGACATCAATTCTTCAAGGCCTGTTTTACTAAATGGGACCTATGAT
  GTGCAGGTGACTTCAGGTGGAACATTCATTGGCATTGGACGGAAAACACCAGATTGCCAA
  GGGAACACCAAGTATTTCCGCTGTAAATTCTGCAATTTCACTTATATGGGCAACTCATCC
  ACCGAATTAGAACAACATTTTCTTCAGACTCACCCAAACAAAATAAAAGCTTCTCTCCCC
  TCCTCTGAGGTTGCAAAACCTTCAGAGAAAAACTCTAACAAGTCCATCCCTGCACTTCAA
  TCCAGTGATTCTGGAGACTTGGGAAAATGGCAGGACAAGATAACAGTCAAAGCAGGAGAT
  GACACTCCTGTTGGGTACTCAGTGCCCATAAAGCCCCTCGATTCCTCTAGACAAAATGGT
  ACAGAGGCCACCAGTTACTACTGGTGTAAATTTTGTAGTTTCAGCTGTGAGTCATCTAGC
  TCACTTAAACTGCTAGAACATTATGGCAAGCAGCACGGAGCAGTGCAGTCAGGCGGCCTT
  AATCCAGAGTTAAATGATAAGCTTTCCAGGGGCTCTGTCATTAATCAGAATGATCTAGCC
  AAAAGTTCAGAAGGAGAGACAATGACCAAGACAGACAAGAGCTCGAGTGGGGCTAAAAAG
  AAGGACTTCTCCAGCAAGGGAGCCGAGGATAATATGGTAACGAGCTATAATTGTCAGTTC
  TGTGACTTCCGATATTCCAAAAGCCATGGCCCTGATGTAATTGTAGTGGGGCCACTTCTC
  CGTCATTATCAACAGCTCCATAACATTCACAAGTGTACCATTAAACACTGTCCATTCTGT
  CCCAGAGGACTTTGCAGCCCAGAAAAGCACCTTGGAGAAATTACTTATCCGTTTGCTTGT
  AGAAAAAGTAATTGTTCCCACTGTGCACTCTTGCTTCTGCACTTGTCTCCTGGGGCGGCT
  GGAAGCTCGCGAGTCAAACATCAGTGCCATCAGTGTTCATTCACCACCCCTGACGTAGAT
  GTACTCCTCTTTCACTATGAAAGTGTGCATGAGTCCCAAGCATCGGATGTCAAACAAGAA
  GCAAATCACCTGCAAGGATCGGATGGGCAGCAGTCTGTCAAGGAAAGCAAAGAACACTCA
  TGTACCAAATGTGATTTTATTACCCAAGTGGAAGAAGAGATTTCCCGACACTACAGGAGA
  GCACACAGCTGCTACAAATGCCGTCAGTGCAGTTTTACAGCTGCCGATACTCAGTCACTA
  CTGGAGCACTTCAACACTGTTCACTGCCAGGAACAGGACATCACTACAGCCAACGGCGAA
  GAGGACGGTCATGCCATATCCACCATCAAAGAGGAGCCCAAAATTGACTTCAGGGTCTAC
  AATCTGCTAACTCCAGACTCTAAAATGGGAGAGCCAGTTTCTGAGAGTGTGGTGAAGAGA
  GAGAAGCTGGAAGAGAAGGACGGGCTCAAAGAGAAAGTTTGGACCGAGAGTTCCAGTGAT
  GACCTTCGCAATGTGACTTGGAGAGGGGCAGACATCCTGCGGGGGAGTCCGTCATACACC
  CAAGCAAGCCTGGGGCTGCTGACGCCTGTGTCTGGCACCCAAGAGCAGACAAAGACTCTA
  AGGGATAGTCCCAATGTGGAGGCCGCCCATCTGGCGCGACCTATTTATGGCTTGGCTGTG
  GAAACCAAGGGATTCCTGCAGGGGGCGCCAGCTGGCGGAGAGAAGTCTGGGGCCCTCCCC
  CAGCAGTATCCTGCATCGGGAGAAAACAAGTCCAAGGATGAATCCCAGTCCCTGTTACGG
  AGGCGTAGAGGCTCCGGTGTTTTTTGTGCCAATTGCCTGACCACAAAGACCTCTCTCTGG
  CGAAAGAATGCAAATGGCGGATATGTATGCAACGCGTGTGGCCTCTACCAGAAGCTTCAC
  TCGACTCCCAGGCCTTTAAACATCATTAAACAAAACAACGGTGAGCAGATTATTAGGAGG
  AGAACAAGAAAGCGCCTTAACCCAGAGGCACTTCAGGCTGAGCAGCTCAACAAACAGCAG
  AGGGGCAGCAATGAGGAGCAAGTCAATGGAAGCCCGTTAGAGAGGAGGTCAGAAGATCAT
  CTAACTGAAAGTCACCAGAGAGAAATTCCACTCCCCAGCCTAAGTAAATACGAAGCCCAG
  GGTTCATTGACTAAAAGCCATTCTGCTCAGCAGCCAGTCCTGGTCAGCCAAACTCTGGAT
  ATTCACAAAAGGATGCAACCTTTGCACATTCAGATAAAAAGTCCTCAGGAAAGTACTGGA
  GATCCAGGAAATAGTTCATCCGTATCTGAAGGGAAAGGAAGTTCTGAGAGAGGCAGTCCT
  ATAGAAAAGTACATGAGACCTGCGAAACACCCAAATTATTCACCACCAGGCAGCCCTATT
  GAAAAGTACCAGTACCCACTTTTTGGACTTCCCTTTGTACATAATGACTTCCAGAGTGAA
  GCTGATTGGCTGCGGTTCTGGAGTAAATATAAGCTCTCCGTTCCTGGGAATCCGCACTAC
  TTGAGTCACGTGCCTGGCCTACCAAATCCTTGCCAAAACTATGTGCCTTATCCCACCTTC
  AATCTGCCTCCTCATTTTTCAGCTGTTGGATCAGACAATGACATTCCTCTAGATTTGGCG
  ATCAAGCATTCCAGACCTGGGCCAACTGCAAACGGTGCCTCCAAGGAGAAAACGAAGGCA
  CCACCAAATGTAAAAAATGAAGGTCCCTTGAATGTAGTAAAAACAGAGAAAGTTGATAGA
  AGTACTCAAGATGAACTTTCAACAAAATGTGTGCACTGTGGCATTGTCTTTCTGGATGAA
  GTGATGTATGCTTTGCATATGAGTTGCCATGGTGACAGTGGACCTTTCCAGTGCAGCATA
  TGCCAGCATCTTTGCACGGACAAATATGACTTCACAACACATATCCAGAGGGGCCTGCAT
  AGGAACAATGCACAAGTGGAAAAAAATGGAAAACCTAAAGAGTAA
  
  Clone variation with respect to NM_014112.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014112 unedited
  CGGGTTACGATTTCGTAAACGACTGCACTATAGGCGGCCGCGAAATTCGCACGAGAAAGA
  CTTTTTCTCTCCCCCCCGCAATAATCCAAGATCAACTCTGCAAACAACAGAAGACGGTTC
  ATGGCTTTGGCCGCCGCGCCACCATCTTTCGGGCTGCCGAGGGTGTTCTTGACGATTAAT
  CAACAGATGTACAGATCAGCTCTCAAAATGTCTTCTGTGTCTTCTGAGCATCTTCTAAGA
  CAATTGCATTAGCCTCCTGCTAGTTGACTAATAGAATTAATAATTGTAAAAAGCACTCTA
  AAGCCACATGCCTTATGAAGTCAATGCTGGGTATGATTTTACAAATATGGTCCGGAAAAA
  GAACCCCCCTCTGAGAAACGTTGCAAGTGAAGGCGAGGGCCAGATCCTGGAGCCTATAGG
  TACAGAAAGCAAGGTATCTGGAAAGAACAAAGAATTTTCTGCAGATCAGATGTCAGAAAA
  TACGGATCAGAGTGATGCTGCAGAACTAAATCATAAGGAGGAACATAGCTTGCATGTTCA
  AGATCCATCTTCTAGCAGTAAGAAGGACTTGAAAAGCGCAGTTCTGAGTGAGAAGGCTGG
  CTTCAATTATGAAAGCCCCAGTAAGGGAGGAAACTTTCCCTCCTTTCCGCATGATGAGGT
  GACAGACAGAAATATGTTGGCTTTCTCATCTCCAGCTGCTGGGGGAGTCTGTGAGCCCTT
  GAAGTCTCCGCACAGAGCAGAGGCAGATGACCCTCAAGAATGGCCTGCACCCTCTCAGGG
  GACTCACTGGAGACACAGGAAGATCAGTAGATGTCACCTAAGCTACANGAGCAACAGGGC
  TAGCACAGAGTGGTCAAGCCTATTGTCAAGGTTNGAGCCCAGTTTCAGTGGCCTCAAAAA
  CC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014112 unedited
  GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAATATATATACATT
  TAATATTACTGGAGCTGTATCTGCATTGGATCATAATAGATTATGTGCACATGTGCAATT
  ATAAACATAATGTGCTACCACAGGCTTCAACAAAGAGCTGTTAAAGATACTTTTTTCCCT
  TCTCATTAATATTACCTTAGAAAAGAATCCCCATGCTTGTTTTATAAAAATCTACCTTCA
  CTAAAACAGAACAGTTTAGAACAGAACATCACTATCTTAAAAGTTGATTAAAAAAACTCT
  CAATATGTCATGTAGAGAGAATTGGGCATACTCTTTTCCTTTTGAACTACAGAGTTATCA
  ATTAGAGCTCTGTCCTTTTCTCATATACTTGGAGTCATGTAGTGTCTCTCTCAATCCACA
  ACGTTCTGAGATGGGTTGGCTCTTTATGATTTTTCTATCCCAAACAACAGAATGAATACA
  GAGGTGAGTGATGAGAGAAAGACTGAGAAAAGGAAGAATGAGAACGCATGAGCTGGTCCT
  GGCCTAAAGTTTGATCCAAAGCTCAATTTAGAATATAGACAAATAATTTTAAAATATTTT
  CAGTTTTTAAATGGCACACAATTTTAGCTGGCACATCATTTTCATCACAGGGGAAGCCTT
  TTTCAAGAGAGATAATTCCTAAATCATCATGAAATTCCTCATTAAAAAAAGTTCCGTACC
  ATAATAGCTCGGTTAAAAACACATTTTAGGATAAATAATTCAGAAAATCTAAATTAAAAA
  AATAATTTTAATATTTATTTTTGAGAGAGGGAATAAAGGCTTTTAATATGTCAAAAAAGG
  AGAGGTTAAAGGTATAATAAAATTTTGTTTTTTTCAAAAGCCCACCTTTTTTCCACCCAT
  ATGTTTATTTTGAAGCCAAATGAATTAACATTTCCTCTCACGAGTTGGATAAAATCATCG
  GTACCCTTCCAAAATCCCTTAAGAGGCGCCTCAATTCCGAAGGGATGGTTTCCCGCGCCG
  CCCCTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014112
• Insert Size: 7000 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_014112.1, NP_054831.1
• RefSeq Size: 10011 bp
• RefSeq ORF: 3846 bp
• Locus ID: 7227
• Cytogenetics: 8q23.3
• Domains: GATA, zf-C2H2
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.