CHMP2B (NM_014043) Human Untagged Clone

CAT#: SC115190

CHMP2B (untagged)-Human chromatin modifying protein 2B (CHMP2B)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CHMP2B
• Synonyms: ALS17; CHMP2.5; DMT1; VPS2-2; VPS2B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014043, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGTCCCTCTTCAAGAAGAAAACCGTGGATGATGTAATAAAGGAACAGAATCGAGAGTTACGAGGTA
  CACAGAGGGCTATAATCAGAGATCGAGCAGCTTTAGAGAAACAAGAAAAACAGCTGGAATTAGAAATTAA
  GAAAATGGCCAAGATTGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAA
  CAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGTTACTTCTATGTCTACACAAACAAAAGTGATGAATT
  CCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGTTAACAAGAAGATGGA
  TCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAA
  ATGATCAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGA
  ATCAAGTTCTTGATGAAATTGGAATTGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAG
  CTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAACGGCAACTCAAGGCTTTA
  GGAGTAGATTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014043 unedited
  GTCAGAATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGTTCCCGGTC
  ACCTGAGCTCCGGGTGACGCGGCTGCGGTAGCTGCGNGAACAAGCCTTCCGCGGGTCCTG
  CCTGGCGACCCCGACCTCCTCCTGCTGTCTCTCCGCTCCGCCACCCCGAACCCGCCAAGG
  TCCTGTCCTTTTCCTCCTGTCCTTTGCCAGCGTTGGGCCGGACCGGGCCGAGCCGGGCCG
  CCCGGGCGCAGTCTTTAACCATGGCGTCCCTCTTCAAGAAGAAAACCGTGGATGATGTAA
  TAAAGGAACAGAATCGAGAGTTACGAGGTACACAGAGGGCTATAATCAGAGATCGAGCAG
  CTTTAGAGAAACAAGAAAAACAGCTGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTA
  ATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGA
  GAACTTTTGCTGTAAGTTCAAAAGTTACTTCTATGTCTACACAAACAAAAGTGATGAATT
  CCCAAATGAAGATGGCTGGAGCAATGTCTACCACAGCAAAAACAATGCAGGCAGTTAACA
  AGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGA
  AAATGGAAATGACTGAAGAAATGATCAATGATACACTTGATGACATCTTTGACGGTTCTG
  ATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTNGAA
  ATTCTGGAAAGATGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACGTC
  ANAGGGCTACATCTCAGATGAAGAGAATGAACGGCACTCAGGNNCTTTAGAGTAGTATAG
  TCAAAAGAGTCATACTATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014043 unedited
  AGCTATGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGCAAAAAC
  ATGTGTTTTGTAAAAAAAATCTGCACTGTGCTTGGTTTATACTACATAATTATAAGTAAG
  CAAAATAGTATGACTTCTTTTGACTAATCTACTCCTAAAGCCTTGAGTTGCCGTTCAATC
  TCTTCATCTGAGATTGTAGCCTTTGACGTAGAGGCAGATGGTAAGCTTCGAGCAGCTGAT
  GGAGCTTTGGCCATCTTTCCAGAAATTTCAATTCCAATTTCATCAAGAACTTGATTCACA
  ATATCCTGGCTTTCTTCTTCGTCATCAGAACCGTCAAAGATGTCATCAAGTGTATCATTG
  ATCATTTCTTCAGTCATTTCCATTTTCATGTTTTCCTTCTGGAAATTCTGCATTGTTTGT
  AATGTCTTTTGTGGATCCATCTTCTTGTTAACTGCCTGCATTGTTTTTGCTGTGGTAGAC
  ATTGCTCCAGCCATCTTCATTTGGGAATTCATCACTTTTGTTTGTGTAGACATAGAAGTA
  ACTTTTGAACTTACAGCAAAAGTTCTCGTCTTCTGTTTCCGTAGATGCACAAGTTGTTTG
  GCTAAAACTTTGCAAGCTTCCTTATTACCAATCTTGGCCATTTTCTTAATTTCTAATTCC
  AGCTGTTTTTCTTGTTTCTCTAAAGCTGCTCGATCTCTGATTATAGCCCTCTGTGTACCT
  CGTAACTCTCGATTCTGTTCCTTTATTACATCATCCACGGGTTTCTTCTTGAAGAGGGAC
  GCCATGGTTAAAGACCTGCGCCGGGCGGCCCGGCTCGGNCCGGTCCCGCCCAACCGCTGC
  AAGGGACAGAGAAAAGGACAGGACCTGNCGGGNTCGGGGTGCGNNNACGAAAACNNNCAG
  AGAGTCGGGTCCCCAGCCAGACGCCGAAGGCTGTTTCCACTACCGANNCCGTACCCGAGC
  TAGTGACGGAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014043
• ORF Size: 642 bp
• Insert Size: 890
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014043.2, NP_054762.2
• RefSeq Size: 2410
• RefSeq ORF: 642
• Locus ID: 25978
• Domains: DUF279
• Protein Pathways: Endocytosis
• Gene Summary: This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).