IKBKE (NM_014002) Human Untagged Clone

CAT#: SC115206

IKBKE (untagged)-Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKBKE), transcript variant 1


  "NM_014002" in other vectors (5)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol IKBKE
Synonyms IKK-E; IKK-i; IKKE; IKKI
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_014002 edited
ATGCAGAGCACAGCCAATTACCTGTGGCACACAGATGACCTGCTGGGGCAGGGGGCCACT
GCCAGTGTGTACAAGGCCCGCAACAAGAAATCCGGAGAGCTGGTTGCTGTGAAGGTCTTC
AACACTACCAGCTACCTGCGGCCCCGCGAGGTGCAGGTGAGGGAGTTTGAGGTCCTGCGG
AAGCTGAACCACCAGAACATCGTCAAGCTCTTTGCGGTGGAGGAGACGGGCGGAAGCCGG
CAGAAGGTACTGGTGATGGAGTACTGCTCCAGTGGGAGCCTGCTGAGTGTGCTGGAGAGC
CCTGAGAATGCCTTTGGGCTGCCTGAGGATGAGTTCCTGGTGGTGCTGCGCTGTGTGGTG
GCCGGCATGAACCACCTGCGGGAGAACGGCATTGTGCATCGCGACATCAAGCCGGGGAAC
ATCATGCGCCTCGTAGGGGAGGAGGGGCAGAGCATCTACAAGCTGACAGACTTCGGCGCT
GCCCGGGAGCTGGATGATGATGAGAAGTTCGTCTCGGTCTATGGGACTGAGGAGTACCTG
CATCCCGACATGTATGAGCGGGCGGTGCTTCGAAAGCCCCAGCAAAAAGCGTTCGGGGTG
ACTGTGGATCTCTGGAGCATTGGAGTGACCTTGTACCATGCAGCCACTGGCAGCCTGCCC
TTCATCCCCTTTGGTGGGCCACGGCGGAACAAGGAGATCATGTACCGGATCACCACGGAG
AAGCCGGCTGGGGCCATTGCAGGTGCCCAGAGGCGGGAGAACGGGCCCCTGGAGTGGAGC
TACACCCTCCCCATCACCTGCCAGCTGTCACTGGGGCTGCAGAGCCAGCTGGTGCCCATC
CTGGCCAACATCCTGGAGGTGGAGCAGGCCAAGTGCTGGGGCTTCGACCAGTTCTTTGCG
GAGACCAGTGACATCCTGCAGCGAGTTGTCGTCCATGTCTTCTCCCTGTCCCAGGCAGTC
CTGCACCACATCTATATCCATGCCCACAACACGATAGCCATTTTCCAGGAGGCCGTGCAC
AAGCAGACCAGTGTGGCCCCCCGACACCAGGAGTACCTCTTTGAGGGTCACCTCTGTGTC
CTCGAGCCCAGCGTCTCAGCACAGCACATCGCCCACACGACGGCAAGCAGCCCCCTGACC
CTCTTCAGCACAGCCATCCCTAAGGGGCTGGCCTTCAGGGACCCTGCTCTGGACGTCCCC
AAGTTCGTCCCCAAAGTGGACCTGCAGGCGGATTACAACACTGCCAAGGGCGTGTTGGGC
GCCGGCTACCAGGCCCTGCGGCTGGCACGGGCCCTGCTGGATGGGCAGGAGCTAATGTTT
CGGGGGCTGCACTGGGTCATGGAGGTGCTCCAGGCCACATGCAGACGGACTCTGGAAGTG
GCAAGGACATCCCTCCTCTACCTCAGCAGCAGCCTGGGAACTGAGAGGTTCAGCAGCGTG
GCTGGAACGCCTGAGATCCAGGAACTGAAGGCGGCTGCAGAACTGAGGTCCAGGCTGCGG
ACTCTAGCGGAGGTCCTCTCCAGATGCTCCCAAAATATCACGGAGACCCAGGAGAGCCTG
AGCAGCCTGAACCGGGAGCTGGTGAAGAGCCGGGATCAGGTACATGAGGACAGAAGCATC
CAGCAGATTCAGTGCTGTTTGGACAAGATGAACTTCATCTACAAACAGTTCAAGAAGTCT
AGGATGAGGCCAGGGCTTGGCTACAACGAGGAGCAGATTCACAAGCTGGATAAGGTGAAT
TTCAGTCATTTAGCCAAAAGACTCCTGCAGGTGTTCCAGGAGGAGTGCGTGCAGAAGTAT
CAAGCGTCCTTAGTCACACACGGCAAGAGGATGAGGGTGGTGCACGAGACCAGGAACCAC
CTGCGCCTGGTTGGCTGTTCTGTGGCTGCCTGTAACACAGAAGCCCAGGGGGTCCAGGAG
AGTCTCAGCAAGCTCCTGGAAGAGCTATCTCACCAGCTCCTTCAGGACCGAGCAAAGGGG
GCTCAGGCCTCGCCGCCTCCCATAGCTCCTTACCCCAGCCCTACACGAAAGGACCTGCTT
CTCCACATGCAAGAGCTCTGCGAGGGGATGAAGCTGCTGGCATCTGACCTCCTGGACAAC
AACCGCATCATCGAACGGCTAAATAGAGTCCCAGCACTTCCTGATGTCTGA
>OriGene 5' read for NM_014002 unedited
AGCATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGNAAAAAACCC
ACTAGTCCCAGCTCCTGGGGTGGCACAGACATTGCAACTGGCCCTGCCTGTGGGTCCTAG
GGGCCCTTGGCTACCAGGAGGCTAAGAACACTGCTCATGAATGACAGTGAGCCCTGAAAG
CTCTGGGGGTGTCACCCAGTCCCACAAGCCTGCATCCCCTGCAGTGGAGATGGGCTCAGC
TCCTGGACGTGCCACAGACAGAAAGCATAACATACACTCGCCAGGAAGAGCCTTTGCCTG
ACTCAGGGCAGCTCAGAGTGTGGGGCAGAAGGTGACCAGCCAGCTCAGGGCAGGAGATGC
AGAGCACAGCCAATTACCTGTGGCACACAGATGACCTGCTGGGGCAGGGGGCCACTGCCA
GTGTGTACAAGGCCCGCAACAAGAAATCCGGAGAGCTGGTTGCTGTGAAGGTCTTCAACA
CTACCAGCTACCTGCGGCCCCGCGAGGTGCAGGTGAGGGAGTTTGAGGTCCTGCGGAAGC
TGAACCACCAGAACATCGTCAAGCTCTTTGCGGTGGAGGAGACGGGCGGAAGCCGGCAGA
AGGTACTGGTGATGGAGTACTGCTCCAGTGGGAGCCTGCTGAGTGTGCTGGAGAGCCCTG
AGAATGCCTTTGGGCTGCCTGAGGATGAGTTCCTGGTGGTGCTGCGCTGTGTGGTGGCCG
GCATGAACCACCTGCGGGAGAACGGCATTGTGCATCGCGACATCAAGCCGGNGACATCAT
GCGCCTNCCTTAAGGGAAGGAGGGGCAGAGCATCTACNAGCTGACAGACTTTCGCGCTGC
CCGGGAGCTGGATGATGATGAGAAGTTTCGTCTCGTCTATGGGACTGAGGAGTACCTGCA
TCCCNGAATGTATGAGCCGGGCGTGCTTTCAAAGCCNCCAGCAAAAAGCGTCGNGTGACT
GTTGGATCTCTGGAGCATGGANTGACCTTGTACAGN
>OriGene 3' read for NM_014002 unedited
AGTCTTGNACCGCGCCGCAATCTANATCGAGTTTTTTTTTTTTTTTTTTAACAAAAGCAA
AGGCCACATTTATTCCACTTCTTGAAGGTGCAGGCCTTGGACCTGCCCAGACTCACAGTC
CTGGCTGCATGTCCCAGGACCAGCTGGAGCCTCAGAGAGTGAGGGAGAGCCAAAGGGGCC
CCAAGACACTGGCACTGGCCTTGGCCACCCATTTTCTCAACTTTAGGCTCAGTCAGACCA
AGCATAGAAAGAACAGGAGGCTCTCTATGTTGCCTGAGGCTGGCAGTGGTGACCCTCAGA
AATCACAAGGGAGCGGAGAGAGCTGTGTTCAACATGAAACGCTTGAAGAGGAAGGAAGAC
TGTGATGAGGTCGTTTGACCTACTGCCCTGGGGAAACCCCAGGAGGCCTCCTCTCCTGTT
GGCTAGGGAGTGAAGTCCTATAAACCAGAGGGAGTGGGAAGGCGTATGAGAGCTTCTTCT
CCCCACGGCCCAGCCATGGGCATGGAGGAGCAGTACCTGAGCCTAGAGAAGATAGAAAGG
TCAGCCAGGCAGTTGCTGCCACACTCTTTCCTGTGGGTCCCAACAGAGGTGGCCTGGTGC
CCAGTCTCAGCTGTGCTGCTTCCCAGGGAGAAAGGCAGTGGAAGGTAATGCTGGCGACAT
CCTGGCCAGCAGCCAGGAGGGAGGTAGGCTGATGTGATGGGAATGGGATCTTGCCCTGGG
TTGGTCTCATGGTGCAGAAGAGCAGTGTTGGAATCATTCTAATGCTTCAGGATGCCTCAT
GTGCCCCATGGAGCTCAGACATCAGGAAGTGCTGGGACTCTATTTAGCCGTCGATGATGC
GGTTTGTGTCCAAGAGTCAGATGCCGCAGCTTCATCCCTCGCAGACTCTGCATGTGGAGA
GCAGTCCTTTCTGTAGGCTTGGGTAAGGACTATGGGAGCGGCCAGCCTGACCCCCT
Restriction Sites NotI-NotI     
ACCN NM_014002
ORF Size 2151 bp
Insert Size 4000
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_014002.2, NP_054721.1
RefSeq Size 3263
RefSeq ORF 2151
Locus ID 9641
Domains pkinase
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway
Gene Summary IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]). [supplied by OMIM, Oct 2009]
Transcript Variant: This variant (1) is the longest transcript and it encodes the longest protein (isoform 1).

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