NCKAP1 (NM_013436) Human Untagged Clone

CAT#: SC115236

NCKAP1 (untagged)-Human NCK-associated protein 1 (NCKAP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NCKAP1
• Synonyms: HEM2; NAP1; NAP125; p125Nap1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115236 sequence for NM_013436 edited (data generated by NextGen Sequencing)
  ATGTCGCGCTCAGTGCTGCAGCCCAGTCAGCAGAAGCTGGCGGAGAAGCTCACCATCCTC
  AACGACCGGGGCGTCGGCATGCTCACCCGCCTCTACAACATCAAGAAGGCATGTGGAGAC
  CCCAAGGCAAAACCATCCTATCTTATCGACAAAAACCTGGAATCTGCTGTGAAATTCATA
  GTCAGAAAATTCCCTGCTGTAGAAACCCGCAACAACAATCAACAGCTTGCACAACTACAG
  AAAGAAAAATCAGAGATTCTGAAAAATCTGGCATTATATTACTTCACATTTGTAGATGTT
  ATGGAATTTAAGGACCATGTTTGTGAATTGCTGAATACTATTGACGTTTGCCAAGTCTTC
  TTTGATATTACTGTAAACTTTGATTTAACAAAGAACTACTTAGATTTAATTATAACCTAT
  ACAACACTAATGATACTGCTGTCTCGAATTGAAGAAAGGAAGGCAATCATTGGATTATAC
  AACTATGCCCATGAAATGACTCATGGAGCAAGTGACAGAGAATACCCACGCCTTGGCCAG
  ATGATTGTGGATTATGAAAACCCTTTAAAGAAGATGATGGAAGAATTTGTACCCCATAGC
  AAGTCTCTTTCAGATGCACTAATTTCTCTTCAAATGGTATATCCTCGAAGGAATCTTTCA
  GCTGACCAGTGGAGAAATGCCCAGTTATTGAGCCTCATCAGTGCACCTAGTACAATGCTT
  AATCCAGCACAGTCCGACACTATGCCTTGTGAATACCTCTCTTTGGATGCAATGGAAAAG
  TGGATTATCTTTGGCTTTATTTTGTGCCATGGGATCCTAAATACTGACGCTACAGCACTG
  AACCTTTGGAAACTAGCTCTTCAAAGTAGCTCTTGCCTCTCTCTCTTTCGGGATGAAGTT
  TTCCACATTCACAAAGCTGCAGAAGACTTATTTGTAAACATACGAGGCTATAATAAACGT
  ATTAATGACATAAGAGAATGCAAGGAGGCAGCCGTGTCACATGCTGGTTCAATGCACAGA
  GAAAGACGCAAGTTTTTAAGATCTGCACTGAAGGAATTGGCTACTGTCCTCTCTGATCAA
  CCTGGATTGCTAGGTCCCAAGGCACTTTTTGTTTTTATGGCATTATCCTTTGCCCGTGAT
  GAAATCATCTGGCTACTTCGTCATGCAGATAACATGCCAAAGAAGAGTGCAGACGACTTT
  ATAGATAAGCACATTGCTGAATTAATATTTTACATGGAAGAACTTAGAGCACATGTGAGG
  AAATACGGACCTGTAATGCAGAGGTATTACGTGCAGTACCTTTCTGGCTTTGATGCTGTT
  GTCCTCAATGAACTCGTGCAGAATCTTTCTGTTTGCCCTGAAGATGAATCAATCATCATG
  TCCTCTTTTGTTAACACTATGACTTCCCTAAGTGTAAAACAAGTTGAAGATGGGGAAGTA
  TTTGATTTCAGAGGAATGAGATTAGATTGGTTTAGGTTACAGGCATATACTAGTGTCTCA
  AAGGCTTCACTTGGCCTTGCAGATCACAGAGAACTTGGAAAGATGATGAATACAATAATT
  TTTCATACAAAAATGGTAGATTCCTTGGTGGAAATGTTGGTGGAAACATCAGATCTCTCC
  ATATTTTGTTTTTATAGTCGTGCTTTTGAGAAGATGTTTCAACAGTGTTTGGAGTTACCC
  TCTCAATCAAGATACTCAATTGCATTTCCACTACTTTGCACTCATTTTATGAGTTGCACG
  CATGAACTATGTCCAGAAGAGCGACATCATATTGGAGATCGCAGTCTTTCCTTATGTAAT
  ATGTTCCTAGATGAAATGGCCAAACAAGCTCGAAATCTCATCACTGATATTTGCACAGAA
  CAGTGTACCCTTAGTGACCAGTTGCTACCCAAGCATTGTGCCAAAACTATCAGTCAAGCA
  GTGAATAAGAAATCAAAAAAGCAGACTGGTAAGAAAGGGGAACCTGAAAGGGAGAAACCA
  GGTGTTGAGAGCATGAGGAAAAACAGGCTGGTTGTGACCAACCTTGATAAATTGCACACT
  GCACTTTCTGAGTTATGCTTCTCTATAAATTATGTACCAAACATGGTGGTATGGGAACAT
  ACCTTTACCCCACGAGAATATTTGACTTCTCATCTGGAAATACGCTTTACCAAGTCAATT
  GTTGGGATGACTATGTATAATCAAGCCACACAGGAAATTGCAAAACCTTCAGAACTTCTA
  ACAAGTGTAAGAGCATACATGACCGTACTCCAGTCAATAGAAAACTATGTGCAGATTGAT
  ATTACAAGAGTATTTAATAATGTGCTTCTTCAACAAACACAACATTTAGACAGTCATGGA
  GAGCCAACCATTACAAGTCTATACACAAATTGGTATTTGGAAACTTTGTTACGACAAGTC
  AGCAATGGCCATATAGCATATTTTCCTGCAATGAAAGCGTTTGTGAACTTACCTACAGAA
  AATGAATTAACATTCAATGCAGAGGAATATTCTGACATATCAGAAATGAGGTCATTATCA
  GAACTACTAGGCCCATATGGTATGAAGTTTCTAAGTGAAAGCCTTATGTGGCATATTTCA
  TCACAAGTTGCTGAACTTAAGAAACTTGTGGTGGAGAATGTTGATGTGTTAACACAAATG
  AGGACCAGCTTTGACAAACCAGACCAGATGGCTGCACTGTTTAAAAGATTATCATCTGTT
  GACAGTGTCTTGAAGAGGATGACAATAATTGGTGTAATTTTATCCTTCCGATCATTGGCA
  CAAGAAGCACTTAGAGATGTGTTATCCTACCACATTCCTTTTCTTGTAAGTTCAATTGAA
  GATTTTAAGGATCACATTCCAAGGGAAACTGATATGAAGGTTGCAATGAATGTGTATGAG
  TTATCATCAGCTGCCGGATTACCTTGTGAGATTGATCCTGCATTGGTCGTAGCTCTTTCT
  TCACAAAAATCGGAAAACATTAGTCCAGAAGAAGAGTATAAAATTGCCTGCCTTCTCATG
  GTGTTTGTGGCAGTTTCTTTGCCAACACTGGCCAGTAATGTGATGTCTCAGTACAGCCCT
  GCTATAGAAGGGCATTGCAACAACATACATTGCTTGGCCAAAGCCATCAACCAGATTGCT
  GCAGCTTTGTTTACAATTCACAAAGGAAGCATTGAAGACCGTCTTAAAGAATTTCTGGCG
  CTTGCATCCTCCAGTCTACTGAAAATTGGCCAGGAGACAGATAAAACTACAACAAGAAAT
  AGAGAATCTGTTTATTTACTGCTAGATATGATTGTACAAGAATCTCCATTCCTTACAATG
  GATCTTTTGGAATCTTGTTTTCCTTATGTCTTGCTGAGAAATGCATACCATGCTGTCTAC
  AAACAAAGTGTTACATCTTCTGCATAA
  
  Clone variation with respect to NM_013436.3
  2781 c=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013436 unedited
  NGTCGGCTTTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGCCGGGGCGC
  GGGCTGCTGCGGGAGAAGGGCTCCGAGGAGTCCGCCGCGGCTCGCTCTGTCGCCGGCGCG
  GGATTGGGGCGCGAGGGCCATGGGCGCGCTCTCCTAAGGCGGAGGTCGCGGGCGGGAGGG
  GAGGAGGCCCGAGAGAGGCTGCTGCGAAGGCCGCGGGCCCGTGACTGGGCGCGAGGCGGC
  CGGCGGCGGCGGCGGCACCAGCACCACCATGTCGCGCTCAGTGCTGCAGCCCAGTCAGCA
  GAAGCTGGCGGAGAAGCTCACCATCCTCAACGACCGGGGCGTCGGCATGCTCACCCGCCT
  CTACAACATCAAGAAGCAAGGACAAGTTTGGAAGGCATGTGGAGACCCCAAGGCAAAACC
  ATCCTATCTTATCGACAAAAACCTGGAATCTGCTGTGAAATTCATAGTCAGAAAATTCCC
  TGCTGTAGAAACCCGCAACAACAATCAACAGCTTGCACAACTACAGAAAGAAAAATCAGA
  GATTCTGAAAAATCTGGCATTATATTACTTCACATTTGTAGATGTTATGGAATTTAAGGA
  CCATGTTTGTGAATTGCTGAATACTATTGACGTTTGCCAAGTCTTCTTTGATATTACTGT
  AAACTTTGATTTAACANAGAACTACTTAGATTTAATTATAACCTATACCACACTAATGAT
  ACTGCTGTCTCGAANTGNAGAAAGGGAAGGCATCATTTGGATATACAACTATGCCCATGA
  AATGACTCATGGGAGCAGTGACAGAGAATACCCACGCCTTGGGCCAGATGATGTGGNATN
  ATGAAACCCCTTTAAGAAGATGATGGNANGAATTTGTACCCCATAGCAAGTCTCCTTCAG
  AGCACTAATC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_013436 unedited
  CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGTGATACAGTCTAGTGTTT
  ATTTTATGTTATGGAAGGTACACTTGAATTTCAAAAATTTAAAACATATATAAAAAGTGG
  TTAGGGACTAACATTTGTATCAACAGTTGATAAATGTCTAAGATTGTTTATTATACAGCA
  GGGTACAATGGTAGTGCTAATGCCAACAGGGCACCATGGAAGTTAGTCTAAAAATTATCG
  CTAGGCTTTATACAAGCAACAACATATGCTGCTGCTCTTAAAATTTTGGGAAATGATCTG
  CTTCTAATACTAAGCAGTTCTTTAACATTTTTAAATGTTATACAGTGTTACAGTATTTAG
  TTTGGCAAATGTTTCAAAATAAAGTAGAAATGTATTCATAACATCACAGAAATGCACATC
  CAATGTTGTTTTCAATAAGAACCATAGGTACAGATCAGAACTCTTCCCTATATGAAATAA
  TTTACACACAGATGAATGCTATAATATCACTATCTAAAATAATCACTAAATACAGTTCTT
  TTTCAGAAATAAACAAGCAAAGATTTTTTTCATTATCAAATATCAAAAACATGTTGATAA
  TGTATGTTTTTCAAATAAATGATACTTTAAAATTATAGGAATAATCTCAGTGAATTCAGT
  GAATGTGCAACCTAAATCAACCAAGTATACTGTAGTACAACCATATTAAGAAACCAATGA
  TCAGAAAATACAACCGTATGAAAGAAATTTATAATCCACAAAACTTTTTCAGGTCTTAAG
  GTAAAATAGCTCCACAGTCTACAGGTAAAACCAAGGGCACANAAATGCGTGCTTATCTTG
  ATTAAGTANNGTATTCTATGCAGAAGATGTACACTTTGTTTGTAGCAGCATGTTATGCAT
  TTCTCAGCAGACTAAGGAAACAGATTCCAAGATCATTGTAGGATGGAGATCTTGACATCA
  TTCTAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_013436
• ORF Size: 3387 bp
• Insert Size: 4200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_013436.3, NP_038464.1
• RefSeq Size: 4619
• RefSeq ORF: 3387
• Locus ID: 10787
• Protein Families: Druggable Genome
• Protein Pathways: Regulation of actin cytoskeleton
• Gene Summary: Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).