ATG4B (NM_013325) Human Untagged Clone

CAT#: SC115281

ATG4B (untagged)-Human ATG4 autophagy related 4 homolog B (S. cerevisiae) (ATG4B), transcript variant 1


  "NM_013325" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ATG4B
Synonyms APG4B; AUTL1
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC115281 sequence for NM_013325 edited (data generated by NextGen Sequencing)
ATGGACGCAGCTACTCTGACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCT
GAGACCTCAGAGCCCGTTTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGAC
GAGATCTTGTCTGATGTGGCATCTAGACTTTGGTTTACATACAGGAAAAACTTTCCAGCC
ATTGGGGGGACAGGCCCCACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACAG
ATGATCTTTGCCCAAGCCCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAA
AGGAAGAGGCAGCCAGACAGCTACTTCAGCGTCCTCAACGCATTCATCGACAGGAAGGAC
AGTTACTACTCCATTCACCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGGC
CAGTGGTACGGGCCCAACACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACG
TGGAGCTCCTTGGCGGTCCACATTGCAATGGACAACACTGTTGTGATGGAGGAAATCAGA
AGGTTGTGCAGGACCAGCGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGAC
CGGCACTGCAACGGATTCCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGA
CCCCTGGTACTTCTCATTCCCCTGCGCCTGGGGCTCACGGACATCAACGAGGCCTACGTG
GAGACGCTGAAGCACTGCTTCATGATGCCCCAGTCCCTGGGCGTCATCGGAGGGAAGCCC
AACAGCGCCCACTACTTCATCGGCTACGTTGGTGAGGAGCTCATCTACCTGGACCCCCAC
ACCACGCAGCCAGCCGTGGAGCCCACTGATGGCTGCTTCATCCCGGACGAGAGCTTCCAC
TGCCAGCACCCGCCGTGCCGCATGAGCATCGCGGAGCTTGACCCGTCCATCGCTGTGGGG
TTTTTCTGTAAGACTGAAGATGACTTCAATGATTGGTGCCAGCAAGTCAAAAAGCTGTCT
CTGCTTGGAGGTGCCCTGCCCATGTTTGAGCTGGTGGAGCAGCAGCCTTCACATCTGGCC
TGCCCCGACGTCCTGAACCTGTCCCTAGATTCTTCTGATGTAGAGCGACTGGAAAGATTC
TTCGACTCAGAAGATGAAGACTTTGAAATCCTGTCCCTTTGA

Clone variation with respect to NM_013325.4
1061 t=>a
>OriGene 5' read for NM_013325 unedited
CTATAGGGGCGGCCGCGAATTCGCACGAGGCCGGACTGGGAAGATGGACGCAGCTACTCT
GACCTACGACACTCTCCGGTTTGCTGAGTTTGAAGATTTTCCTGAGACCTCAGAGCCCGT
TTGGATACTGGGTAGAAAATACAGCATTTTCACAGAAAAGGACGAGATCTTGTCTGATGT
GGCATCTAGACTTTGGTTTACATACAGGAAAAACTTTCCAGCCATTGGGGGGACAGGCCC
CACCTCGGACACAGGCTGGGGCTGCATGCTGCGGTGTGGACAGATGATCTTTGCCCAAGC
CCTGGTGTGCCGGCACCTAGGCCGAGATTGGAGGTGGACACAAAGGAAGAGGCAGCCAGA
CAGCTACTTCAGCGTCCTCAACGCATTCATCGACAGGAAGGACAGTTACTACTCCATTCA
CCAGATAGCGCAAATGGGAGTTGGCGAAGGCAAGTCCATAGGCCAGTGGTACGGGCCCAA
CACTGTCGCCCAGGTCCTGAAGAAGCTTGCTGTCTTCGATACGTGGAGCTCCTTGGCGGT
CCACATTGCAATGGACAACACTGTTGTGATGGAGGAAATCAGAAGGTTGTGCAGGACCAG
CGTTCCCTGTGCAGGCGCCACTGCGTTTCCTGCAGATTCCGACCGGCACTGCAACGGATT
CCCTGCCGGAGCTGAGGTCACCAACAGGCCGTCGCCATGGAGACCCCTGGTACTTCTCAT
TCCCCTGCGCCTGNNGCTCACGGACATCAACGAGGCCTACGTGGAGACGCTGAAGCACTG
CTTCATGATGCCCNCAGTCCTGGGGCGTCATCGGGAGGGAAGCCCNACAGCGCCACTACT
TCATCGGT
>OriGene 3' read for NM_013325 unedited
CCCTGAAGGGTNATTTATCTCCTTACAACCACANAACCGGCGCCTGGGAGCAGTGGGACT
GAGGCCCAGGTGCTAACACGGGGCTGGCAGTGTCGAGAGAACGCTCTGGAAGCTCCTAAC
AGACGGCTCCGCGTGCGGATGCACAGGCCCTGACGGGCACTCTGAGCTGGGCAGTCTGAC
ACCAAGCAGTAAGGCCTCCCGGGCAGCGCAGCCTCAGTCCACGAGCACAGCGGGTGGCCC
TCTGGGGGGAGGCAGCACGGGGCGCAGCCCTCGGCAGGCGAGCGGGCGGGATGGATGAAA
CGCAGCGGCACCAGGAGCCCCAGGCTCTCACAGGTGCCACCCCCGACCCCAGGATTTTCA
AAGGGACAGGATTTCAAAGTCTTCATCTTCTGAGTCGAAGAATCTTTCCAGTCGCTCTAC
ATCAGAAGAATCTAGGGACAGGTTCAGGACGTCGGGGCAGGCCAGATGTGAAGGCTGCTG
CTCCACCAGCTCAAACATGGGCAGGGCACCTCCAAGCAGAGACAGCTTTTTGACTTGCTG
GCACCAATCATTGAAGTCATCTTCAGTCTTACAGAAAAACCCCACAGCGATGGACGGGTC
AAGCTCCGCGATGCTCATGCGGCACGGCGGGTGCTGGCAGTGGAAGCTCTCGTCCGGGAT
GAAGCAGCCATCAGTGGGCTCCACGGCTGGCTGCGTGGTGTGGGGGTCCAGGTAGATGAG
CTCCTCACCAACGTAGCCGATGAAGTAGTGGGCGCTGTTGGGCTTCCCTCCGATGACGCC
CAGGGACTGGGGCATCATGAAGCAGTGCTTCAGCGNTCTCACGTAGGCCTCGTTGATGTC
CGTGAGCCCCAGGCGCATGGGAATGAGAAGTACCAGGGGTCTCCATGGCGACAGCCTGTT
GGTGACCTCAGCTCCGGCAAGGAATCCGTTGCAATGCCGGTCGGATCTGCAG
Restriction Sites NotI-NotI     
ACCN NM_013325
ORF Size 1182 bp
Insert Size 1600
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_013325.4, NP_037457.3
RefSeq Size 2892
RefSeq ORF 1182
Locus ID 23192
Domains Peptidase_C54
Protein Families Protease
Protein Pathways Regulation of autophagy
Gene Summary Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (1) is the predominant transcript and it encodes the longer isoform (a).

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