Neurokinin B (TAC3) (NM_013251) Human Untagged Clone

CAT#: SC115350

TAC3 (untagged)-Human tachykinin 3 (TAC3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TAC3
• Synonyms: HH10; NKB; NKNB; PRO1155; ZNEUROK1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_013251 edited
  ATGAGGATCATGCTGCTATTCACAGCCATCCTGGCCTTCAGCCTAGCTCAGAGCTTTGGG
  GCTGTCTGTAAGGAGCCACAGGAGGAGGTGGTTCCTGGCGGGGGCCGCAGCAAGAGGGAT
  CCAGATCTCTACCAGCTGCTCCAGAGACTCTTCAAAAGCCACTCATCTCTGGAGGGATTG
  CTCAAAGCCCTGAGCCAGGCTAGCACAGATCCTAAGGAATCAACATCTCCCGAGAAACGT
  GACATGCATGACTTCTTTGTGGGACTTATGGGCAAGAGGAGCGTCCAGCCAGACTCTCCT
  ACGGATGTGAATCAAGAGAACGTCCCCAGCTTTGGCATCCTCAAGTATCCCCCGAGAGCA
  GAATAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013251 unedited
  CACCAGCTCCACTCGGTTTCTCTCTTTGCAGGAGCACCGGCAGCACCAGTGTGTGAGGGG
  AGCAGGCAGCGGTCCTAGCCAGTTCCTTGATCCTGCCAGACCACCCAGCCCCCGGCACAG
  AGCTGCTCCACAGGCACCATGAGGATCATGCTGCTATTCACAGCCATCCTGGCCTTCAGC
  CTAGCTCAGAGCTTTGGGGCTGTCTGTAAGGAGCCACAGGAGGAGGTGGTTCCTGGCGGG
  GGCCGCAGCAAGAGGGATCCAGATCTCTACCAGCTGCTCCAGAGACTCTTCAAAAGCCAC
  TCATCTCTGGAGGGATTGCTCAAAGCCCTGAGCCAGGCTAGCACAGATCCTAAGGAATCA
  ACATCTCCCGAGAAACGTGACATGCATGACTTCTTTGTGGGACTTATGGGCAAGAGGAGC
  GTCCAGCCAGACTCTCCTACGGATGTGAATCAAGAGAACGTCCCCAGCTTTGGCATCCTC
  AAGTATCCCCCGAGAGCAGAATAGGTACTCCACTTCCGGACTCCTGGACTGCATTAGGAA
  GACCTCTTTCCCTGTCCCAATCCCCAGGTGCGCACGCCTCCTGTTACCCTTTCTCTTCCC
  TGTTCTTGTACATNTCTTGTGCTTTGACTCCTTCTCCATCTTTTCTACCTGACCCTGGTG
  TGGAAACTGCATAGTGAATATCCCCAACCCCAATGGGCATTGACTGTAGAATACCCTAGA
  GTTCCTGTAGTGTCCTACATTAAAAATATAATGTCTCTCTCTATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_013251
• Insert Size: 900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_013251.2, NP_037383.1
• RefSeq Size: 832 bp
• RefSeq ORF: 366 bp
• Locus ID: 6866
• Cytogenetics: 12q13.3
• Domains: Neurokinin_B
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: 'This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]'
  Transcript Variant: This variant (1) encodes the longer isoform (1).