CD168 (HMMR) (NM_012485) Human Untagged Clone

CAT#: SC115375

HMMR (untagged)-Human hyaluronan-mediated motility receptor (RHAMM) (HMMR), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HMMR
• Synonyms: CD168; IHABP; RHAMM
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012485, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCCTTTCCTAAGGCGCCCTTGAAACGATTCAATGACCCTTCTGGTTGTGCACCATCTCCAGGTGCTT
  ATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGATTTAAACAACA
  AAAAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAG
  TCTTCGGAATCAAAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCCAGGATCTGG
  AAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAAAAACATCTCTCTCTGCAAA
  TAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTAATGAACTACTAAAATCTAAGTTTTCT
  GAAAATGGTAACCAGAAGAATTTGAGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAA
  CAAAGATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAGTCT
  CGAAGAGTCTCAAGGGAAAATAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGAT
  GAAAAATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATCAAGTGGAAA
  AATACAAGCTAGATATTGCCCAGTTAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTTTAAGCCTTAA
  GCAGTCTCTTGAGGAGAATATTGTTATATTATCTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTG
  CTTGAAAAAGAAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAAATCTAAATGCAGAGATGC
  AAAACTTAAAACAGAAGTTTATTCTTGAACAACAGGAACGTGAAAAGCTTCAACAAAAAGAATTACAAAT
  TGATTCACTTCTGCAACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTTTTCAAGAG
  GAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAGAATTAAAGCAAACACTGGATGAGCTTGATAAATTAC
  AGCAAAAGGAGGAACAAGCTGAAAGGCTGGTCAAGCAATTGGAAGAGGAAGCAAAATCTAGAGCTGAAGA
  ATTAAAACTCCTAGAAGAAAAGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAGTAGTGCTGCTCATACC
  CAGGCCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGGTGCAAAGCCTTGAAGATGTTACTGCTCAAT
  TTGAAAGCTATAAAGCGTTAACAGCCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCATCATTACAGGA
  AAAAGCGGCCAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATCAGATTTTGGCAACTGAGAGCTCAAAT
  CAAGAATATGTAAGGATGCTTCTAGATCTGCAGACCAAGTCAGCACTAAAGGAAACAGAAATTAAAGAAA
  TCACAGTTTCTTTTCTTCAAAAAATAACTGATTTGCAGAACCAACTCAAGCAACAGGAGGAAGACTTTAG
  AAAACAGCTGGAAGATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAACAGCAGAATTAACTGAAGAA
  ATTAACAAGTGGCGTCTCCTCTATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAACTAGATG
  CTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTGCAGCTCAGGAACAGCTAAATAAAATAAG
  AGATTCATATGCTAAATTATTGGGTCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGAAGTTGAAA
  GATGAAAATAGCCAACTCAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTGCTAAAAAAAAACAAAGTG
  AGACAAAACTTCAAGAGGAATTGAATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAAAGGCTTTTCA
  TCATGAAAGTAAAGAAAATTTTGCCCTGAAGACCCCATTAAAAGAAGGCAATACAAACTGTTACCGAGCT
  CCTATGGAGTGTCAAGAATCATGGAAGTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012485 unedited
  NNGGTTCAAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGCCAGTC
  ACCTTCAGTTTCTGGAGCTGGCCGTCAACATGTCCTTTCCTAAGGCGCCCTTGAAACGAT
  TCAATGACCCTTCTGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAG
  TATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGATTTAAACAACAAAAAGAATCTA
  AACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAGT
  CTTCGGAATCAAAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCC
  AGGATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAA
  AAACATCTCTCTCTGCAAATAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGA
  CTAATGAACTACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATTTGAGAATTC
  TAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAACAAAGATGAGGGGTATGATGG
  CTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAGTCTCGAAGAGTCTC
  AAGGGAAAATAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGATG
  AANAATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATC
  AAGTGGAAAAATACAAGCTAGATATTGCCCAGTTAGAAGAAATTTGAAGAGAAGATGATG
  AATTNNTAGCCTTAGCAGTCTCTTGAGGAGATATTGNTATATATCTAACAGNTAGAGAAC
  TAATG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012485 unedited
  GGCTTCTGTGTATTTTTTTCATTTACACAAAGTTAATCAAATGCTGAGTAGACATGCAGA
  TGACAAGCAGTNATATGACAAACTCTGAAGAAATAGTTACATGTAGAGTTTCTCAGATTT
  TTAGTGTATCTAAGAATTAACTGAAGAGTTTGTTAAGAATGCAGGCTTAAAGGCCAATCC
  ACAGATTATAATTTCATACAAACAGGATGGAGCCTAAGAACCTGTAAATTATTAAACAAC
  TGATTAAAAATAGAGAGGTTTCTATGAAGTTAGGCTTGTCCTTATTTCTTATTTGAACTG
  GACAAGTAGAAGGATAATAGGTAGGACCAAGTGAGCATTATCAGAATCAAAGTAGAGGCA
  ATAACAAGCCAAGGTGTTTTAGCCTAGCTAAAGAAGCTCAGACTAGAAAAGACCTCCAGG
  ATCAAGCTGAAGAATCTGGGGTTTAGACTCTTGAAACTAAGGTTTCAGAACAGGAGGATA
  ATAATATGATACTGACTTTTAAGTTGATGAGATGCATTCTAAGCTGGAAAGCCAGCGAAA
  GGGTTCAGAATGAGGTGATAAAGGTGAGCATTAGGGAGGAGGTATTTGCAAGAAAAAATA
  AAATGTCAAAAGACACTTTGGTAAAAAATGTTCCTTTCACATATTTAAGGATTGGCAGTT
  AAAATTAAATACAACATTATAAAATACCCATGTCAAATATAATAACAGCAACATCAATAA
  CAACAAGACGAATGAAATAATCTTCAACAGGTTTCTCAGATGTTTACTTCCATGATTCTT
  GACACTCCATAGGAGCTCGGGGTACAGTTGTATTGCCTTCTTTTATGGNNGGTCTCAGGN
  CANAATTTTCTTTACTTTCATGATGAANAGCCTTTGAGGATCAAAGTGTTTGATACCTAG
  AAACTTATTCAATNCTNCTGAAGTNTTGNCTCACTNTGTTTTTTTTAGCAGCTGACAGCG
  AGTTTGAATCTTCGATNGATGGCTATTTCATCTTCAACTTACACAGCTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012485
• Insert Size: 3000 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012485.1, NP_036617.1
• RefSeq Size: 2957 bp
• RefSeq ORF: 2130 bp
• Locus ID: 3161
• Cytogenetics: 5q34
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: ECM-receptor interaction
• Gene Summary: 'The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]'
  Transcript Variant: This variant (3) is missing an in-frame coding exon compared to transcript variant 1, resulting in an isoform (c) which lacks an internal 16 aa segment compared to isoform a.