CD168 (HMMR) (NM_012485) Human Untagged Clone

CAT#: SC115375

HMMR (untagged)-Human hyaluronan-mediated motility receptor (RHAMM) (HMMR), transcript variant 3


  "NM_012485" in other vectors (6)

Reconstitution Protocol

USD 1,440.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol HMMR
Synonyms CD168; IHABP; RHAMM
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_012485, the custom clone sequence may differ by one or more nucleotides


ATGTCCTTTCCTAAGGCGCCCTTGAAACGATTCAATGACCCTTCTGGTTGTGCACCATCTCCAGGTGCTT
ATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGATTTAAACAACA
AAAAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAG
TCTTCGGAATCAAAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCCAGGATCTGG
AAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAAAAACATCTCTCTCTGCAAA
TAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTAATGAACTACTAAAATCTAAGTTTTCT
GAAAATGGTAACCAGAAGAATTTGAGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAA
CAAAGATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAGTCT
CGAAGAGTCTCAAGGGAAAATAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGAT
GAAAAATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATCAAGTGGAAA
AATACAAGCTAGATATTGCCCAGTTAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTTTAAGCCTTAA
GCAGTCTCTTGAGGAGAATATTGTTATATTATCTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTG
CTTGAAAAAGAAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAAATCTAAATGCAGAGATGC
AAAACTTAAAACAGAAGTTTATTCTTGAACAACAGGAACGTGAAAAGCTTCAACAAAAAGAATTACAAAT
TGATTCACTTCTGCAACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTTTTCAAGAG
GAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAGAATTAAAGCAAACACTGGATGAGCTTGATAAATTAC
AGCAAAAGGAGGAACAAGCTGAAAGGCTGGTCAAGCAATTGGAAGAGGAAGCAAAATCTAGAGCTGAAGA
ATTAAAACTCCTAGAAGAAAAGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAGTAGTGCTGCTCATACC
CAGGCCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGGTGCAAAGCCTTGAAGATGTTACTGCTCAAT
TTGAAAGCTATAAAGCGTTAACAGCCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCATCATTACAGGA
AAAAGCGGCCAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATCAGATTTTGGCAACTGAGAGCTCAAAT
CAAGAATATGTAAGGATGCTTCTAGATCTGCAGACCAAGTCAGCACTAAAGGAAACAGAAATTAAAGAAA
TCACAGTTTCTTTTCTTCAAAAAATAACTGATTTGCAGAACCAACTCAAGCAACAGGAGGAAGACTTTAG
AAAACAGCTGGAAGATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAACAGCAGAATTAACTGAAGAA
ATTAACAAGTGGCGTCTCCTCTATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAACTAGATG
CTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTGCAGCTCAGGAACAGCTAAATAAAATAAG
AGATTCATATGCTAAATTATTGGGTCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGAAGTTGAAA
GATGAAAATAGCCAACTCAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTGCTAAAAAAAAACAAAGTG
AGACAAAACTTCAAGAGGAATTGAATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAAAGGCTTTTCA
TCATGAAAGTAAAGAAAATTTTGCCCTGAAGACCCCATTAAAAGAAGGCAATACAAACTGTTACCGAGCT
CCTATGGAGTGTCAAGAATCATGGAAGTAA


>OriGene 5' read for NM_012485 unedited
NNGGTTCAAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGCCAGTC
ACCTTCAGTTTCTGGAGCTGGCCGTCAACATGTCCTTTCCTAAGGCGCCCTTGAAACGAT
TCAATGACCCTTCTGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAG
TATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGATTTAAACAACAAAAAGAATCTA
AACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAGT
CTTCGGAATCAAAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCC
AGGATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAA
AAACATCTCTCTCTGCAAATAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGA
CTAATGAACTACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATTTGAGAATTC
TAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAACAAAGATGAGGGGTATGATGG
CTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAGTCTCGAAGAGTCTC
AAGGGAAAATAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGATG
AANAATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATC
AAGTGGAAAAATACAAGCTAGATATTGCCCAGTTAGAAGAAATTTGAAGAGAAGATGATG
AATTNNTAGCCTTAGCAGTCTCTTGAGGAGATATTGNTATATATCTAACAGNTAGAGAAC
TAATG
>OriGene 3' read for NM_012485 unedited
GGCTTCTGTGTATTTTTTTCATTTACACAAAGTTAATCAAATGCTGAGTAGACATGCAGA
TGACAAGCAGTNATATGACAAACTCTGAAGAAATAGTTACATGTAGAGTTTCTCAGATTT
TTAGTGTATCTAAGAATTAACTGAAGAGTTTGTTAAGAATGCAGGCTTAAAGGCCAATCC
ACAGATTATAATTTCATACAAACAGGATGGAGCCTAAGAACCTGTAAATTATTAAACAAC
TGATTAAAAATAGAGAGGTTTCTATGAAGTTAGGCTTGTCCTTATTTCTTATTTGAACTG
GACAAGTAGAAGGATAATAGGTAGGACCAAGTGAGCATTATCAGAATCAAAGTAGAGGCA
ATAACAAGCCAAGGTGTTTTAGCCTAGCTAAAGAAGCTCAGACTAGAAAAGACCTCCAGG
ATCAAGCTGAAGAATCTGGGGTTTAGACTCTTGAAACTAAGGTTTCAGAACAGGAGGATA
ATAATATGATACTGACTTTTAAGTTGATGAGATGCATTCTAAGCTGGAAAGCCAGCGAAA
GGGTTCAGAATGAGGTGATAAAGGTGAGCATTAGGGAGGAGGTATTTGCAAGAAAAAATA
AAATGTCAAAAGACACTTTGGTAAAAAATGTTCCTTTCACATATTTAAGGATTGGCAGTT
AAAATTAAATACAACATTATAAAATACCCATGTCAAATATAATAACAGCAACATCAATAA
CAACAAGACGAATGAAATAATCTTCAACAGGTTTCTCAGATGTTTACTTCCATGATTCTT
GACACTCCATAGGAGCTCGGGGTACAGTTGTATTGCCTTCTTTTATGGNNGGTCTCAGGN
CANAATTTTCTTTACTTTCATGATGAANAGCCTTTGAGGATCAAAGTGTTTGATACCTAG
AAACTTATTCAATNCTNCTGAAGTNTTGNCTCACTNTGTTTTTTTTAGCAGCTGACAGCG
AGTTTGAATCTTCGATNGATGGCTATTTCATCTTCAACTTACACAGCTG
Restriction Sites NotI-NotI     
ACCN NM_012485
Insert Size 3000 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_012485.1, NP_036617.1
RefSeq Size 2957 bp
RefSeq ORF 2130 bp
Locus ID 3161
Cytogenetics 5q34
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways ECM-receptor interaction
Gene Summary 'The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]'
Transcript Variant: This variant (3) is missing an in-frame coding exon compared to transcript variant 1, resulting in an isoform (c) which lacks an internal 16 aa segment compared to isoform a.

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