CMT (ICMT) (NM_012405) Human Untagged Clone

CAT#: SC115419

ICMT (untagged)-Human isoprenylcysteine carboxyl methyltransferase (ICMT)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ICMT
• Synonyms: HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115419 sequence for NM_012405 edited (data generated by NextGen Sequencing)
  ATGGCGGGCTGCGCGGCGCGGGCTCCGCCGGGCTCTGAGGCGCGTCTCAGCCTCGCCACC
  TTCCTGCTGGGCGCCTCGGTGCTCGCGCTGCCGCTGCTCACGCGCGCCGGCCTGCAGGGC
  CGCACCGGGCTGGCGCTCTACGTGGCCGGGCTCAACGCGCTGCTGCTGCTGCTCTATCGG
  CCGCCTCGCTACCAGATAGCCATCCGAGCTTGTTTCCTGGGGTTTGTGTTCGGCTGCGGC
  ACGCTGCTAAGTTTTAGCCAGTCTTCTTGGAGTCACTTTGGCTGGTACATGTGCTCCCTG
  TCATTGTTCCACTATTCTGAATACTTGGTGACAGCAGTCAATAATCCCAAAAGTCTGTCC
  TTGGATTCCTTTCTCCTGAATCACAGCCTGGAGTATACAGTAGCTGCTCTTTCTTCTTGG
  TTAGAGTTCACACTTGAAAATATCTTTTGGCCAGAACTGAAGCAGATTACCTGGCTCAGT
  GTCACAGGGCTGCTGATGGTGGTCTTCGGAGAATGTCTGAGGAAGGCGGCCATGTTTACA
  GCTGGCTCCAATTTCAACCACGTGGTACAGAATGAAAAATCAGATACACATACTCTGGTG
  ACCAGTGGAGTGTACGCTTGGTTTCGGCATCCTTCTTACGTCGGGTGGTTTTACTGGAGT
  ATTGGAACTCAGGTGATGCTGTGTAACCCCATCTGCGGCGTCAGCTATGCCCTGACAGTG
  TGGCGATTCTTCCGCGATCGAACAGAAGAAGAAGAAATCTCACTAATTCACTTTTTTGGA
  GAGGAGTACCTGGAGTATAAGAAGAGGGTGCCCACGGGCCTGCCTTTCATAAAGGGGGTC
  AAGGTGGACCTGTGA
  
  Clone variation with respect to NM_012405.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012405 unedited
  NCGTTCGAGATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCGCCGC
  CCGCTAGTCCGCCGCCCGGCGCCATGGCGGGCTGCGCGGCGCGGGCTCCGCCGGGCTCTG
  AGGCGCGTCTCAGCCTCGCCACCTTCCTGCTGGGCGCCTCGGTGCTCGCGCTGCCGCTGC
  TCACGCGCGCCGGCCTGCAGGGCCGCACCGGGCTGGCGCTCTACGTGGCCGGGCTCAACG
  CGCTGCTGCTGCTGCTCTATCGGCCGCCTCGCTACCAGATAGCCATCCGAGCTTGTTTCC
  TGGGGTTTGTGTTCGGCTGCGGCACGCTGCTAAGTTTTAGCCAGTCTTCTTGGAGTCACT
  TTGGCTGGTACATGTGCTCCCTGTCATTGTTCCACTATTCTGAATACTTGGTGACAGCAG
  TCAATAATCCCAAAAGTCTGTCCTTGGATTCCTTTCTCCTGAATCACAGCCTGGAGTATA
  CAGTAGCTGCTCTTTCTTCTTGGTTAGAGTTCACACTTGAAAATATCTTTTGGCCAGAAC
  TGAAGCAGATTACCTGGCTCAGTGTCACAGGGCTGCTGATGGTGGTCTTCGGAGAATGTC
  TGAGGAAGGCGGCCATGTTTACAGCTGGCTCCAATTTCAACCACGTGGTACAGAATGAAA
  AATCAGATACACATACTCTGGTGACCAGTGGAGTGTACGCTTGGTTTCGGCATCCTTCTT
  ACGTCGGGTGGTTTTACTGGAGTATTGGAACTCANGTGATGCTGTGTAACCNCATCTGCG
  GCGTCAGCTATGCCCTGACAGTGTGGCGATTCTTCCGCGATCGAACAGAAGAAGAAGAAA
  TCTCACTAATTCACTTTTTTGGAGAGGAGTACCTGGAGTATAAGAAGAGGGTGCCCACGG
  GCCTGCCTTTCATAAGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012405 unedited
  TTAAATAACTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTCAAAAAATAAGTCATATTTCGGAGTTGAAAAAAGGCTTTTTTGAACATACTTTTT
  AGGGTTCGGGCCCAATTAACCAAATGTCGGCCCTTTTTTGGGGAGCTTTAAAACAGAACA
  TTTTTTTTTGGGGGCCCCCCCACATTTGAGGATAAAAAACATTTGAAATTGTTTTTTTAA
  GCCCCAAAAACCCCCCGGGGAGGGAGGGGGTTTTGACCCCTTTCCACAAATGGGGAGGTC
  TAGGCCCGGAAAGGTTTAGGGGCTCCCCACAGGCCGGGGGGGGGGGCAACAAAGGGGGGC
  TTTGGCCCCGCCCCAACCCCGCCTTAAAATTAACACTTTTTAAGGGCCCCCGAAACACTG
  GAGGGGAGGTTCTCACCCTGAGGCCAATTTCCTGTCTATTCCAAAATGAACCCAGCGTCC
  CACCTCTTAAAGCTTCGAGGGGGGACTAAAAGCCAATTTACTCTCCCAAACTTGCAAAAC
  AAACATACGGGCTGAATCTTATTGGGGACTATTGGCAGTATTAAAAATTATTTTTGAAAG
  CCAATCGGCTTGGATTTGAAGTTGTATATGCCCAAATCCCTTTGGAAAACAGTTTGAAAT
  GACTGGAGGGACAATGTTATTTTGAGAACAAAAACAGAAAAACAAAATTCTGAGACTGGC
  CTTGAAATTGGAAAATTAAGCTATGGTAAAAGGAANATCAAATCCCAATAAACGGGAAAC
  ACCCCCTTCTAAAGGTTTAAGGCCCCCCCCAGGGCAAGCCTTTCAGTAAGCCCTTTCTTG
  GAACAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012405
• ORF Size: 855 bp
• Insert Size: 2650
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012405.2, NP_036537.1
• RefSeq Size: 3547
• RefSeq ORF: 855
• Locus ID: 23463
• Domains: ICMT
• Protein Families: Transmembrane
• Gene Summary: This gene encodes the third of three enzymes that posttranslationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longer isoform (1) of this protein.