TC10 (RHOQ) (NM_012249) Human Untagged Clone

CAT#: SC115459

RHOQ (untagged)-Human ras homolog gene family, member Q (RHOQ)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RHOQ
• Synonyms: ARHQ; HEL-S-42; RASL7A; TC10; TC10A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_012249 edited
  ATGGCTCACGGGCCCGGCGCGCTGATGCTCAAGTGCGTGGTGGTCGGCGACGGGGCGGTG
  GGCAAGACGTGCCTACTCATGAGCTATGCCAACGACGCCTTCCCGGAGGAGTACGTGCCC
  ACCGTCTTCGACCACTACGCAGTCAGCGTCACCGTGGGGGGCAAGCAGTACCTCCTAGGA
  CTCTATGACACGGCCGGACAGGAAGACTATGACCGTCTGAGGCCTTTATCTTACCCAATG
  ACCGATGTCTTCCTTATATGCTTCTCGGTGGTAAATCCAGCCTCATTTCAAAATGTGAAA
  GAGGAGTGGGTACCGGAACTTAAGGAATACGCACCAAATGTACCCTTTTTATTAATAGGA
  ACTCAGATTGATCTCCGAGATGACCCCAAAACTTTAGCAAGACTGAATGATATGAAAGAA
  AAACCTATATGTGTGGAACAAGGACAGAAACTAGCAAAAGAGATAGGAGCATGCTGCTAT
  GTGGAATGTTCAGCTTTAACCCAGAAGGGATTGAAGACTGTTTTTGATGAGGCTATCATA
  GCCATTTTAACTCCAAAGAAACACACTGTAAAAAAAAGAATAGGATCAAGATGTATAAAC
  TGTTGTTTAATTACGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012249 unedited
  TTTCGCGATTTGAAACCGATTTACTATAGGCGGCCCGCGAATCGGCACGAGGCCGCGGCG
  GCGGCAGCGCCCCGGGCCCGCCGCCCCCTCCCCTCCTGCGAGGGGAGCCGCTGCATGGGG
  CCGGGGGGGCGGCCCTGCGGCGCGGAGCGGCGGCGACGGCGGCGGACCCCCCAGGCGGGC
  TGGGGCTGAGCCCGGGGCCGGGGCGGGGGCTCCGGGGGGACCATGCCCGGAGGCCGGCCG
  GCAGCAGCATGGCTCACGGGCCCGGCGCGCTGATGCTCAAGTGCGTGGTGGTCGGCGACG
  GGGCGGTGGGCAAGACGTGCCTACTCATGAGCTATGCCAACGACGCCTTCCCGGAGGAGT
  ACGTGCCCACCGTCTTCGACCACTACGCAGTCAGCGTCACCGTGGGGGGCAAGCAGTACC
  TCCTAGGACTCTATGACACGGCCGGACAGGAAGACTATGACCGTCTGAGGCCTTTATCTT
  ACCCAATGACCGATGTCTTCCTTATATGCTTCTCGGTGGTAAATCCAGCCTCATTTCAAA
  ATGTGAAAGAGGAGTGGGTACCGGAACTTAAGGAATACGCACCAAATGTACCCTTTTTAT
  TAATAGGAACTCAGATTGATCTCCGAGATGACCCCAAAACTTTAGCAAGACTGAATGATA
  TGAAAGAAAAACCTATATGTGTGGAACAAGGACAGANACTAGCAAAAGAGATAGGAGCAT
  GCTGCTATGTGGAATGTTCAGCTNTAACCCCAGAAGGATTGAAGACTGTTTTTGATGAGG
  CTATCATAGCCATTTTAACTCCAAAAAAACACACTGTAAAAAAAAGAATAGGGATCAGAT
  GTATAAACTGTTGGTTTATTACGTGAGAAACATCTTCAGTGCCCAGAACTGGCCATTNCT
  CTCAGAAAGCANAGANATGCTACAGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012249
• ORF Size: 618 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012249.2, NP_036381.2
• RefSeq Size: 2127
• RefSeq ORF: 618
• Locus ID: 23433
• Domains: ras, RAS, RHO, RAB
• Protein Pathways: Insulin signaling pathway
• Gene Summary: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14. [provided by RefSeq, Aug 2011]