HP1 alpha (CBX5) (NM_012117) Human Untagged Clone

CAT#: SC115517

CBX5 (untagged)-Human chromobox homolog 5 (CBX5), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CBX5
• Synonyms: HEL25; HP1; HP1A
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_012117 edited
  ATGGGAAAGAAAACCAAGCGGACAGCTGACAGTTCTTCTTCAGAGGATGAGGAGGAGTAT
  GTTGTGGAGAAGGTGCTAGACAGGCGCGTGGTTAAGGGACAAGTGGAATATCTACTGAAG
  TGGAAAGGCTTTTCTGAGGAGCACAATACTTGGGAACCTGAGAAAAACTTGGATTGCCCT
  GAGCTAATTTCTGAATTTATGAAAAAGTATAAGAAGATGAAGGAGGGTGAAAATAATAAA
  CCCAGGGAGAAGTCAGAAAGTAACAAGAGGAAATCCAATTTCTCAAACAGTGCCGATGAC
  ATCAAATCTAAAAAAAAGAGAGAGCAGAGCAATGATATCGCTCGGGGCTTTGAGAGAGGA
  CTGGAACCAGAAAAGATCATTGGGGCAACAGATTCCTGTGGTGATTTAATGTTCCTAATG
  AAATGGAAAGACACAGATGAAGCTGACCTGGTTCTTGCAAAAGAAGCTAATGTGAAATGT
  CCACAAATTGTGATAGCATTTTATGAAGAGAGACTGACATGGCATGCATATCCTGAGGAT
  GCGGAAAACAAAGAGAAAGAAACAGCAAAGAGCTAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012117 unedited
  NTTGTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCTTGTG
  GTGCGGCCTCACCATACAGGAACAGGGCAGACGTTAGCGTGAGTGATCACTCTCAATCCC
  GGGGACCTGGTGGCCTTAGTCTTTCAGGTGGAACGGTGTGCGACATGGGAAAGAAAACCA
  AGCGGACAGCTGACAGTTCTTCTTCAGAGGATGAGGAGGAGTATGTTGTGGAGAAGGTGC
  TAGACAGGCGCGTGGTTAAGGGACAAGTGGAATATCTACTGAAGTGGAAAGGCTTTTCTG
  AGGAGCACAATACTTGGGAACCTGAGAAAAACTTGGATTGCCCTGAGCTAATTTCTGAAT
  TTATGAAAAAGTATAAGAAGATGAAGGAGGGTGAAAATAATAAACCCAGGGAGAAGTCAG
  AAAGTAACAAGAGGAAATCCAATTTCTCAAACAGTGCCGATGACATCAAATCTAAAAAAA
  AGAGAGAGCAGAGCAATGATATCGCTCGGGGCTTTGAGAGAGGACTGGAACCAGAAAAGA
  TCATTGGGGCAACAGATTCCTGTGGTGATTTAATGTTCCTAATGAAATGGAAAGACACAG
  ATGAAGCTGACCTGGTTCTTGCAAAAGAAGCTAATGTGAAATGTCCACAAATTGTGATAG
  CATTTTATGAAGAGAGACTGACATGGCATGCATATCCTGAGGATGCGGAAAACAAAGAGA
  AAGAAACAGCAAAGAGCTAAAGGAGGGGATGGGTCTCTGTCATTTCTCTTTGTACATAAT
  ACATTCACCTCCCTGCCTTCTCTCCTTTCTACCCACCCCTTTCTATCCTAAACACATNCA
  TAAAAAATGTGCTTATCACTGTGCTCCACAGGAAAAGTTGGTATGGNTTCTCTTGTACAT
  ACTGAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012117
• ORF Size: 576 bp
• Insert Size: 6200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012117.1, NP_036249.1
• RefSeq Size: 876
• RefSeq ORF: 576
• Locus ID: 23468
• Domains: CHROMO
• Gene Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence and transcripts to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.