CD2AP (NM_012120) Human Untagged Clone

CAT#: SC115518

CD2AP (untagged)-Human CD2-associated protein (CD2AP)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD2AP
• Synonyms: CMS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012120, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTTGACTATATTGTGGAGTATGACTATGATGCTGTACATGATGATGAATTAACTATTCGAGTTGGAG
  AAATCATCAGGAATGTGAAAAAGCTACAGGAGGAAGGGTGGCTGGAAGGAGAACTAAATGGGAGAAGAGG
  AATGTTCCCTGACAATTTCGTTAAGGAAATTAAAAGAGAGACGGAATTCAAGGATGACAGTTTGCCCATC
  AAACGGGAAAGGCATGGGAATGTAGCAAGTCTTGTACAACGAATAAGCACCTATGGACTTCCAGCTGGAG
  GAATTCAGCCACATCCACAAACCAAAAACATTAAGAAGAAGACCAAGAAGCGTCAGTGTAAAGTTCTTTT
  TGAGTACATTCCACAAAATGAGGATGAACTGGAGCTGAAAGTGGGAGATATTATTGATATTAATGAAGAG
  GTAGAAGAAGGCTGGTGGAGTGGAACCCTGAATAACAAGTTGGGACTGTTTCCCTCAAATTTTGTGAAAG
  AATTAGAGGTAACAGATGATGGTGAAACTCATGAAGCCCAGGACGATTCAGAAACTGTTTTGGCTGGGCC
  TACTTCACCTATACCTTCTCTGGGAAATGTGAGTGAAACTGCATCTGGATCAGTTACACAGCCAAAGAAA
  ATTCGAGGAATTGGATTTGGAGACATTTTTAAAGAAGGCTCTGTGAAACTTCGGACAAGAACATCCAGTA
  GTGAAACAGAAGAGAAAAAACCAGAAAAGCCCTTAATCCTACAGTCACTGGGACCCAAAACTCAGAGTGT
  GGAGATAACAAAAACAGATACCGAAGGTAAAATTAAAGCTAAAGAATATTGTAGAACATTATTTGCCTAT
  GAAGGTACTAATGAAGATGAACTTACTTTTAAAGAGGGGGAGATAATCCATTTGATAAGTAAGGAGACTG
  GAGAAGCTGGCTGGTGGAGGGGCGAACTTAATGGTAAAGAAGGAGTATTTCCAGACAATTTTGCTGTCCA
  GATAAATGAACTTGATAAAGACTTTCCAAAACCAAAGAAACCACCACCTCCTGCTAAGGCTCCAGCTCCA
  AAGCCTGAACTGATAGCTGCAGAGAAGAAATATTTTTCTTTAAAGCCTGAAGAAAAGGATGAAAAATCAA
  CACTGGAACAGAAACCTTCTAAACCAGCAGCTCCACAAGTCCCACCCAAGAAACCTACTCCACCTACCAA
  AGCCAGTAATTTACTGAGATCTTCTGGAACAGTGTACCCAAAGCGACCTGAAAAACCAGTTCCTCCACCA
  CCTCCTATAGCCAAGATTAATGGGGAAGTTTCTAGCATTTCATCAAAATTTGAAACTGAGCCAGTATCAA
  AACTAAAGCTAGATTCTGAACAGCTGCCCCTTAGACCAAAATCAGTAGACTTTGATTCACTTACAGTAAG
  GACCTCCAAAGAAACAGATGTTGTAAATTTTGATGACATAGCTTCCTCAGAAAACTTGCTTCATCTCACT
  GCAAATAGACCAAAGATGCCTGGAAGAAGGTTGCCGGGCCGTTTCAATGGTGGACATTCTCCAACTCACA
  GCCCCGAAAAAATCTTGAAGTTACCAAAAGAAGAAGACAGTGCCAACCTGAAGCCATCTGAATTAAAAAA
  AGATACATGCTACTCTCCAAAGCCATCTGTGTACCTTTCAACACCTTCCAGTGCTTCTAAAGCAAATACA
  ACTGCTTTCCTGACTCCATTAGAAATCAAAGCTAAAGTGGAAACAGATGATGTGAAAAAAAATTCCCTGG
  ATGAACTTAGAGCCCAGATTATTGAATTGTTGTGCATTGTAGAAGCACTGAAAAAGGATCACGGGAAAGA
  ACTGGAAAAACTGCGAAAAGATTTGGAAGAAGAGAAGACAATGAGAAGTAATCTAGAGATGGAAATAGAG
  AAGCTGAAAAAAGCTGTCCTGTCTTCTTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012120 unedited
  GTCAAATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGCAGCATGGTTG
  ACTATATTGTGGAGTATGACTATNATGCTGTACATGATGATGAATTAACTATTCGAGTTG
  GAGAAATCATCAGGAATGTGAAAAAGCTACAGGAGGAAGGGTGGCTGGAAGGAGAACTAA
  ATGGGAGAAGAGGAATGTTCCCTGACAATTTCGTTAAGGAAATTAAAAGAGAGACGGAAT
  TCAAGGATGACAGTTTGCCCATCAAACGGGAAAGGCATGGGAATGTAGCAAGTCTTGTAC
  AACGAATAAGCACCTATGGACTTCCAGCTGGAGGAATTCAGCCACATCCACAAACCAAAA
  ACATTAAGAAGAAGACCAAGAAGCGTCAGTGTAAAGTTCTTTTTGAGTACATTCCACAAA
  ATGAGGATGAACTGGAGCTGAAAGTGGGAGATATTATTGATATTAATGAAGAGGTAGAAG
  AAGGCTGGTGGAGTGGAACCCTGAATAACAAGTTGGGACTGTTTCCCTCAAATTTTGTGA
  AAGAATTAGAGGTAACAGATGATGGTGAAACTCATGAAGCCCAGGACGATTCAAAAACTG
  TTTTGGCTGGGCCTACTTCACCTATACCTTCTCTGGGAAATGTGAGTGAAACTGCATCTG
  GTTCAGTTACACAGCCAAAGAAAATTCGAGGAATTGGATTTGGAGACATTTTTAAAGAAG
  GCTCTGTGANACTTNCGGACAGACATCCAGTAGTGAAACAGAAGAGAAAAACCAGAAAGC
  CCTTATCCTACAGTCACTGGGACCCANACTCANAGTGTGGAGATNACANAACAGATACCG
  AAGTAAAATTAAGCTAAAGATATTGTAGACATTATTGCTATGANGGTACTAATGAGAGAA
  CTACTTTAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012120 unedited
  ACATTCAACTGGGCATTATGTAACANNGTTATTGAAAGCAAGTCAGGGTAAAATTTTATA
  GCCAAAAATATTCATAGCAGCAACTTTTAAAATATGATTTTATTAAATCAAGTCATTGCA
  CTTGGTCATTTTATTGCTACAGCAAAACAAGGCCTTTACATTATAATACTTCTCATTTCT
  GATTTAACTGATTGTCTCATTCTGCTCATACATTTCAAGTTTAAATGCAAGCATAAAATG
  TTTATCAACAAATCTAGAGAGCACTTGGATTTTTAATTTTTCTGTGATCACAGTAAGGAG
  CATAAAAAAGAGTATCTTCTGTTACACAAGGCCTGTTCTCTCTTTACATCTTCAGACTTA
  AATTCTGTAGAAGGTAACAGCTTTGTATTAAGACAGAAGCTTAGTGGTCACAAACAAAAA
  ATAACACTGAAATACAATTCGGAAATTAATGATACTGTGTGTCTCAAAGAATACCTGAAC
  TATACATTCACTAATAATTTGGCAATGAGATTCCATGCTGTTCAACTTTTGTCTTTTATA
  CTCACACGTAGAAAAAAAATTCATGATTTACCCCAAGGTTATTATTAAATATCATTTTGT
  GATATGAACTNNTAGTATAGAAATTAATACATTTCCCATACCAACAGAAAGTAAAGTGCT
  AGAATAAAGGATCATTNTTCCCATCANGCCTGNGTTTGTTTGGGTTTTCTTACTATTTTA
  TCAAGGACAGAAAGGGTAAAGTATTTCAGTTACCTTTTCTATTCTGACTGAGGGAGACAC
  CAGCAAAAACTTTAAATACATTTCCATGCTCATAAGCATNNCTGATTCATGTACTATTGA
  GAAAATGACCACCAAAACTTTAGAACAGCCTGAAACTGCTGNAAACTTCCTCATCCCATA
  TAGGATGACCAGGNATCACTTCATNGATTTTCAGGTGAAAAAGCTGAGAATAATNCTAGA
  TACAAATTTTTGTTTACCTAGGTTGCCTTAAAGGAAGAGATTATTTTTTTACGAAGAAAT
  AATCTTTGCTGNCCTTTACCTTNCCTTTACGAAAGGACATTTA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012120
• ORF Size: 1920 bp
• Insert Size: 5520
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012120.1, NP_036252.1
• RefSeq Size: 5425
• RefSeq ORF: 1920
• Locus ID: 23607
• Domains: SH3
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008]