TDP43 (TARDBP) (NM_007375) Human Untagged Clone

CAT#: SC115570

TARDBP (untagged)-Human TAR DNA binding protein (TARDBP)


  "NM_007375" in other vectors (7)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TARDBP
Synonyms ALS10; TDP-43
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC115570 sequence for NM_007375 edited (data generated by NextGen Sequencing)
ATGTCTGAATATATTCGGGTAACCGAAGATGAGAACGATGAGCCCATTGAAATACCATCG
GAAGACGATGGGACGGTGCTGCTCTCCACGGTTACAGCCCAGTTTCCAGGGGCGTGTGGG
CTTCGCTACAGGAATCCAGTGTCTCAGTGTATGAGAGGTGTCCGGCTGGTAGAAGGAATT
CTGCATGCCCCAGATGCTGGCTGGGGAAATCTGGTGTATGTTGTCAACTATCCAAAAGAT
AACAAAAGAAAAATGGATGAGACAGATGCTTCATCAGCAGTGAAAGTGAAAAGAGCAGTC
CAGAAAACATCCGATTTAATAGTGTTGGGTCTCCCATGGAAAACAACCGAACAGGACCTG
AAAGAGTATTTTAGTACCTTTGGAGAAGTTCTTATGGTGCAGGTCAAGAAAGATCTTAAG
ACTGGTCATTCAAAGGGGTTTGGCTTTGTTCGTTTTACGGAATATGAAACACAAGTGAAA
GTAATGTCACAGCGACATATGATAGATGGACGATGGTGTGACTGCAAACTTCCTAATTCT
AAGCAAAGCCAAGATGAGCCTTTGAGAAGCAGAAAAGTGTTTGTGGGGCGCTGTACAGAG
GACATGACTGAGGATGAGCTGCGGGAGTTCTTCTCTCAGTACGGGGATGTGATGGATGTC
TTCATCCCCAAGCCATTCAGGGCCTTTGCCTTTGTTACATTTGCAGATGATCAGATTGCG
CAGTCTCTTTGTGGAGAGGACTTGATCATTAAAGGAATCAGCGTTCATATATCCAATGCC
GAACCTAAGCACAATAGCAATAGACAGTTAGAAAGAAGTGGAAGATTTGGTGGTAATCCA
GGTGGCTTTGGGAATCAGGGTGGATTTGGTAATAGCAGAGGGGGTGGAGCTGGTTTGGGA
AACAATCAAGGTAGTAATATGGGTGGTGGGATGAACTTTGGTGCGTTCAGCATTAATCCA
GCCATGATGGCTGCCGCCCAGGCAGCACTACAGAGCAGTTGGGGTATGATGGGCATGTTA
GCCAGCCAGCAGAACCAGTCAGGCCCATCGGGTAATAACCAAAACCAAGGCAACATGCAG
AAGGAGCCAAACCAGGCCTTCGGTTCTGGAAATAACTCTTATAGTGGCTCTAATTCTGGT
GCAGCAATTGGTTGGGGATCAGCATCCAATGCAGGGTCGGGCAGTGGTTTTAATGGAGGC
TTTGGCTCAAGCATGGATTCTAAGTCTTCTGGCTGGGGAATGTAG

Clone variation with respect to NM_007375.3
1082 g=>a
>OriGene 5' read for NM_007375 unedited
NGTTAAATTTGTATACACTCCTATAGGCGGCCGCGCAATTCGCACGAGGGTCGGGCTTCC
CACACGGCCTACGGGAAAGTAAAAGAGTCTGAATATATTCGGGTAACCGAAGAGAGAACG
ATGAGCCCATTGAAATACCATCGGAAGACGATGGGACGGTGCTGCTCTCCACGGTTACAG
CCCAGTTTCCAGGGGCGTGTGGGCTTCGCTACAGGAATCCAGTGTCTCAGTGTATGAGAG
GTGTCCGGCTGGTAGAAGGAATTCTGCATGCCCCAGATGCTGGCTGGGGAAATCTGGTGT
ATGTTGTCAACTATCCAAAAGATAACAAAAGAAAAATGGATGAGACAGATGCTTCATCAG
CAGTGAAAGTGAAAAGAGCAGTCCAGAAAACATCCGATTTAATAGTGTTGGGTCTCCCAT
GGAAAACAACCGAACAGGACCTGAAAGAGTATTTTAGTACCTTTGGAGAAGTTCTTATGG
TGCAGGTCAAGAAAGATCTTAAGACTGGTCATTCAAAGGGGTTTGGCTTTGTTCGTTTTA
CGGAATATGAAACACAAGTGAAAGTAATGTCACAGCGACATATGATAGATGGACGATGGT
GTGACTGCAAACTTCCTAATTCTAAGCAAAGCCAAGATGAGCCTTTGAGAAGCAGAAAAG
TGTTTGTGGGGCGCTGTACAGAGGACATGACTGAGGATGAGCTGCGGGAGTTCTTCTCTC
AGTACGGNGATGTGATGGATGTCTTCATCCCCAAGCCATTCAGGGCCTTTGCCTTTGTTA
CATTTGCAGATGATCAGATTGCGCAGTCTCTTTGTGGAGAGGACTTGATCATTAAGGAAT
CAGCGTTCATTATCCCATGCCGAACCCTAGCACAATAGCATAGAAGTTAGAAAGAGTGGA
AGATTNGTG
>OriGene 3' read for NM_007375 unedited
GGCACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTATTTAAATCAGTTTTATTTAA
GAATTTCCAACAATGACAACTCTTATAAAAAGCATCCAAGCACAGGACACAGAACTGCAG
CAAACAGCATTCTTATGGGTAGCTAACAGACATTAGAACTTCCACCCTTCTTTGAGACAC
CTGAGCTCACTGGTGAACTCTGCTTCAAGTCCTCCTGCAAAGCACACCACAAGCTCAGTC
CATGTTCTCAGCCCATCAGCTTCAGTTCACATTGCCACACTTACATATCAGTAACAGAAG
AGAACACACACCATACAGCATTCACAGCAGTTGACAAAGGGGTAGGGGGAGTACAAGTAT
CATTTCACTTAACACATTCATCTAATGTGGGTTATCTAAGAACAAAAACTCACTTAAAAG
TCTTCCAACAGATGTGGATGTCCTTTGAATGCAAAAAACATTCGTACATTATTTGCTATC
ATTGCTCTCTGCACACTCTCTCACCAAAGCCACAGGATTGAGAGACACATCTCGCCAAGT
TAAAAAATATCCATTATGCACCACCAAGTCTCTGCACGCGCTCTCTCCTTTTCTCGCTCA
TACTAGCCTTTCATGCCTCGGCACCACCATCAATCCCACACAAGGTTTCAAAAGTTCAGA
CAGCCTTCTGGTTCCATATCACAGCCTTGCGTTCATAGCGTTGATACGACTCCATGAAAT
ANAGAGTAGCGGATAAAAATGGGACACCCACCGTCAAAGACGCGGCCTGTGATGCGTGAT
GACGAATTCTTGATGAGAAAGCTTAGACAGTATCCTATGCAGATATTACACACTACTTCA
TGAGNNGCTCCCATAACATTGAATGAAGACTGCGAGATAAGAAGCTCTATGACTTTGGTT
GAGGAGACAGGTAAACAACAAGACAACTGGCACTGAC
Restriction Sites NotI-NotI     
ACCN NM_007375
ORF Size 1245 bp
Insert Size 3110
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq NM_007375.3, NP_031401.1
RefSeq Size 4236
RefSeq ORF 1245
Locus ID 23435
Domains RRM
Protein Families Transcription Factors
Gene Summary HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008]

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