DRP1 (DNM1L) (NM_012062) Human Untagged Clone

CAT#: SC115574

DNM1L (untagged)-Human dynamin 1-like (DNM1L), transcript variant 1


  "NM_012062" in other vectors (6)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol DNM1L
Synonyms DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_012062 edited
GGCGAACTGTGGGCCCCGGCCCCATTCATTGCCGTGGCCGGCGGGCACTGGGGCCCCGTG
TTTTCAGAGTCATGGAGGCGCTAATTCCTGTCATAAACAAGCTCCAGGACGTCTTCAACA
CGGTGGGCGCCGACATCATCCAGCTGCCTCAAATCGTCGTAGTGGGAACGCAGAGCAGCG
GAAAGAGCTCAGTGCTAGAAAGCCTGGTGGGGAGGGACCTGCTTCCCAGAGGTACTGGAA
TTGTCACCCGGAGACCTCTCATTCTGCAACTGGTCCATGTTTCACAAGAAGATAAACGGA
AAACAACAGGAGAAGAAAATGGGGTGGAAGCAGAAGAATGGGGTAAATTTCTTCACACCA
AAAATAAGCTTTACACGGATTTTGATGAAATTCGACAAGAAATTGAAAATGAAACAGAAA
GAATTTCAGGAAATAATAAGGGAGTAAGCCCTGAACCAATTCATCTTAAGATTTTTTCAC
CCAACGTTGTCAATTTGACACTTGTGGATTTGCCAGGAATGACCAAGGTGCCTGTAGGTG
ATCAACCTAAGGATATTGAGCTTCAAATCAGAGAGCTCATTCTTCGGTTCATCAGTAATC
CTAATTCCATTATCCTCGCTGTCACTGCTGCTAATACAGATATGGCAACATCAGAGGCAC
TTAAAATTTCAAGAGAGGTAGATCCAGATGGTCGCAGAACCCTAGCTGTAATCACTAAAC
TTGATCTCATGGATGCGGGTACTGATGCCATGGATGTATTGATGGGAAGGGTTATTCCAG
TCAAACTTGGAATAATTGGAGTAGTTAACAGGAGCCAGCTAGATATTAACAACAAGAAGA
GTGTAACTGATTCAATCCGTGATGAGTATGCTTTTCTTCAAAAGAAATATCCATCTCTGG
CCAATAGAAATGGAACAAAGTATCTTGCTAGGACTCTAAACAGGTTACTGATGCATCACA
TCAGAGATTGTTTACCAGAGTTGAAAACAAGAATAAATGTTCTAGCTGCTCAGTATCAGT
CTCTTCTAAATAGCTACGGTGAACCCGTGGATGATAAAAGTGCTACTTTACTCCAACTTA
TTACCAAATTTGCCACAGAATATTGTAACACTATTGAAGGAACTGCAAAATATATTGAAA
CTTCGGAGCTATGCGGTGGTGCTAGAATTTGTTATATTTTCCATGAGACTTTTGGGCGAA
CCTTAGAATCTGTTGATCCACTTGGTGGCCTTAACACTATTGACATTTTGACTGCCATTA
GAAATGCTACTGGTCCTCGTCCTGCTTTATTTGTGCCTGAGGTTTCATTTGAGTTACTGG
TGAAGCGGCAAATCAAACGTCTAGAAGAGCCCAGCCTCCGCTGTGTGGAACTGGTTCATG
AGGAAATGCAAAGGATCATTCAGCACTGTAGCAATTACAGTACACAGGAATTGTTACGAT
TTCCTAAACTTCATGATGCCATAGTTGAAGTGGTGACTTGTCTTCTTCGTAAAAGGTTGC
CTGTTACAAATGAAATGGTCCATAACTTAGTGGCAATTGAACTGGCTTATATCAACACAA
AACATCCAGACTTTGCTGATGCTTGTGGGCTAATGAACAATAATATAGAGGAACAAAGGA
GAAACAGGCTAGCCAGAGAATTACCTTCAGCTGTATCACGAGACAAGTCTTCTAAAGTTC
CAAGTGCTTTGGCACCTGCCTCCCAGGAGCCCTCCCCCGCTGCTTCTGCTGAGGCTGATG
GCAAGTTAATTCAGGACAGCAGAAGAGAAACTAAAAATGTTGCATCTGGAGGTGGTGGGG
TTGGAGATGGTGTTCAAGAACCAACCACAGGCAACTGGAGAGGAATGCTGAAAACTTCAA
AAGCTGAAGAGTTATTAGCAGAAGAAAAATCAAAACCCATTCCAATTATGCCAGCCAGTC
CACAAAAAGGTCATGCCGTGAACCTGCTAGATGTGCCAGTTCCTGTTGCACGAAAACTAT
CTGCTCGGGAACAGCGAGATTGTGAGGTTATTGAACGACTCATTAAATCATATTTTCTCA
TTGTCAGAAAGAATATTCAAGACAGTGTGCCAAAGGCAGTAATGCATTTTTTGGTTAATC
ATGTGAAAGACACTCTTCAGAGTGAGCTAGTAGGCCAGCTGTATAAATCATCCTTATTGG
ATGATCTTCTGACAGAATCTGAGGACATGGCACAGCGCAGGAAAGAAGCAGCTGATATGC
TAAAGGCATTACAAGGAGCCAGTCAAATTATTGCTGAAATCCGGGAGACTCATCTTTGGT
GAAGAGAACTATGTAATACTGAGACTTTGTTGACTCAAAACTTGCTAGTTACTGCCTACC
TGAGTAGAATCTTATTTATGAACTCCTGTGTATTGCAATGGTATGAATCTGCTCATGTGG
AGACTGGCTATAAACTGAAAAGTGTATTCCAAATTGCAGAACACATCACACATTTAATCC
AAATAATAAATGGCTGTTTCTAAAGTTTCCCAGTATATATAAAAAAAAA
>OriGene 5' read for NM_012062 unedited
NNNAACGTTCAAATTTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGG
GCGAACTGTGGGCCCCGGCCCCATTCATTGCCGTGGCCGGCGGGCACTGGGGCCCCGTGT
TTTCAGAGTCATGGAGGCGCTAATTCCTGTCATAAACAAGCTCCAGGACGTCTTCAACAC
GGTGGGCGCCGACATCATCCAGCTGCCTCAAATCGTCGTAGTGGGAACGCAGAGCAGCGG
AAAGAGCTCAGTGCTAGAAAGCCTGGTGGGGAGGGACCTGCTTCCCAGAGGTACTGGAAT
TGTCACCCGGAGACCTCTCATTCTGCAACTGGTCCATGTTTCACAAGAAGATAAACGGAA
AACAACAGGAGAAGAAAATGGGGTGGAAGCAGAAGAATGGGGTAAATTTCTTCACACCAA
AAATAAGCTTTACACGGATTTTGATGAAATTCGACAAGAAATTGAAAATGAAACAGAAAG
AATTTCAGGAAATAATAAGGGAGTAAGCCCTGAACCAATTCATCTTAAGATTTTTTCACC
CAACGTTGTCAATTTGACACTTGTGGATTTGCCAGGAATGACCAAGGTGCCTGTAGGTGA
TCAACCTAAGGATATTGAGCTTCAAATCAGAGAGCTCATTCTTCGGTTCATCAGTAATCC
TAATTCCATTATCCTCGCTGTCACTGCTGCTAATACAGATATGGCAACATCAGAGGCACT
TAAAATTTCAAGAGAGGTAGATCCAGATGGTCGCAGAACCCTAGCTGTAATCACTAAACT
TGATCTCATGGATGCGGGTACTGATGCCATGGATGTATTGATGGGGAAGGGTTATTCCAG
TCAAACTTGGAATAATTGGNAGTAGTTAACAGGNAGCCAGCTAGATATTAACAACAGNAA
AAGAGTGTACTGANTNCAATCCCGGGATGAGTATGGCTTTT
>OriGene 3' read for NM_012062 unedited
ATGGCCGCGGCCGCATCTAGGGTCGAGTTTTTTTTTTTTTTTTTATATATACTGGNGAAA
CTTTAGAAACAGCCATTTATTATTTGGATTAAATGTGTGATGTGTTCTGCAATTTGGAAT
ACACTTTTCAGTTTATAGCCAGTCTCCACATGAGCAGATTCATACCATTGCAATACACAG
GAGTTCATAAATAAGATTCTACTCAGGTAGGCAGTAACTAGCAAGTTTTGAGTCAACAAA
GTCTCAGTATTACATAGTTCTCTTCACCAAAGATGAGTCTCCCGGATTTCAGCAATAATT
TGACTGGCTCCTTGTAATGCCTTTAGCATATCAGCTGCTTCTTTCCTGCGCTGTGCCATG
TCCTCAGATTCTGTCAGAAGATCATCCAATAAGGATGATTTATACAGCTGGCCTACTAGC
TCACTCTGAAGAGTGTCTTTCACATGATTAACCAAAAAATGCATTACTGCCTTTGGCACA
CTGTCTTGAATATTCTTTCTGACAATGAGAAAATATGATTTAATGAGTCGTTCAATAACC
TCACAATCTCGCTGTTCCCGAGCAGATAGTTTTCGTGCAACAGGAACTGGCACATCTAGC
AGGTTCACGGCATGACCTTTTTGTGGACTGGCTGGCATAATTGGAATGGGTTTTGATTTT
TCTTCTGCTAATAACTCTTCAGCTTTTGGAGTTTTCAGCATTCCTCCTCAGNTGCCTGTG
GGNTGGTTCTTGGACACCATCTCCAACCCCACCACCTCCAGATGCACATTTTTAGCTTCT
CTCCTGCTGTCCTGAATTACCTTGCATCAGCCTCAGCCAACCACCGGGGGGGGGCTCCCG
CAAGCAGGTGGCCCACCTTGGGACTTAAAAGACCGGCCCGGACCAGCTGAGGCATTTTGG
CCCGCCGGCCCCCTGGTCTTTATCATGGCCACACCCCAGCTTCCCGCCGGGCGTCTGGCC
CGCCAGCCCCCCTTCCCT
Restriction Sites NotI-NotI     
ACCN NM_012062
ORF Size 2211 bp
Insert Size 2500
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_012062.2, NP_036192.1
RefSeq Size 3293
RefSeq ORF 2211
Locus ID 10059
Protein Pathways Endocytosis, Fc gamma R-mediated phagocytosis
Gene Summary This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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