KLHL2 (NM_007246) Human Untagged Clone

CAT#: SC115613

KLHL2 (untagged)-Human kelch-like 2, Mayven (Drosophila) (KLHL2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLHL2
• Synonyms: ABP-KELCH; MAV; MAYVEN
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115613 sequence for NM_007246 edited (data generated by NextGen Sequencing)
  ATGGAGACGCCGCCGCTGCCTCCCGCATGCACAAAGCAGGGTCATCAGAAGCCTCTCGAT
  TCAAAAGATGATAATACCGAAAAACACTGCCCAGTGACAGTGAATCCTTGGCATATGAAG
  AAAGCTTTCAAAGTCATGAACGAATTAAGAAGTCAAAATTTGCTGTGCGATGTCACAATT
  GTGGCAGAAGACATGGAAATTTCTGCTCATAGAGTGGTGCTGGCCGCCTGTAGTCCTTAT
  TTTCATGCCATGTTTACAGGTGAGATGAGTGAGAGCCGAGCAAAGAGAGTTAGAATAAAA
  GAGGTAGATGGCTGGACCCTGAGGATGCTAATTGATTATGTTTACACTGCAGAAATTCAG
  GTTACAGAAGAAAATGTACAGGTACTTCTCCCAGCAGCTGGTCTCTTACAGTTACAGGAT
  GTGAAGAAGACTTGTTGTGAATTTTTGGAATCCCAGCTTCACCCTGTCAACTGCTTAGGA
  ATCCGGGCTTTTGCTGATATGCATGCATGTACCGACCTTCTGAACAAGGCCAACACCTAT
  GCAGAGCAACATTTTGCAGATGTTGTACTTAGTGAAGAATTTCTCAATCTTGGCATCGAA
  CAAGTGTGCAGCTTAATCTCAAGTGACAAACTTACCATTTCTTCAGAAGAGAAGGTATTT
  GAAGCAGTAATAGCATGGGTGAACCATGACAAGGATGTGAGGCAAGAGTTTATGGCCCGA
  CTGATGGAACATGTACGGTTACCTTTGCTTCCTCGGGAATATTTAGTTCAGAGGGTTGAA
  GAGGAAGCATTGGTCAAGAATAGCAGTGCTTGCAAAGATTACCTCATTGAAGCAATGAAG
  TACCATTTGCTGCCAACAGAGCAGCGTATATTAATGAAGAGTGTCCGGACCCGGCTGAGG
  ACACCCATGAACCTTCCCAAATTGATGGTGGTGGTTGGGGGCCAAGCACCAAAGGCTATC
  CGGAGTGTGGAATGCTATGACTTTAAAGAAGAAAGGTGGCACCAAGTAGCAGAGTTGCCT
  TCCAGGAGGTGCAGGGCAGGCATGGTCTACATGGCTGGACTTGTTTTTGCTGTTGGTGGC
  TTTAATGGCTCATTAAGAGTTCGCACTGTAGATTCCTACGACCCTGTGAAGGACCAGTGG
  ACCAGCGTTGCTAACATGAGAGACCGGAGAAGCACTTTGGGAGCTGCTGTGTTAAATGGA
  TTATTATACGCTGTGGGAGGCTTTGATGGGAGTACAGGTTTGTCATCTGTGGAAGCATAC
  AACATAAAGTCTAATGAGTGGTTTCATGTAGCTCCCATGAATACAAGGAGGAGCAGTGTT
  GGTGTGGGTGTTGTTGGAGGTTTGCTCTATGCTGTAGGAGGTTATGATGGAGCATCACGT
  CAGTGTCTTAGCACAGTAGAATGCTATAATGCTACAACAAATGAGTGGACCTATATAGCA
  GAAATGAGCACCAGGCGGAGTGGAGCAGGTGTTGGTGTGTTAAACAATTTATTGTATGCT
  GTAGGAGGTCATGATGGCCCTTTAGTACGAAAAAGTGTTGAAGTATATGATCCCACCACT
  AACGCATGGAGACAGGTTGCAGATATGAACATGTGCAGAAGAAATGCAGGAGTTTGTGCA
  GTTAATGGTCTGTTATATGTTGTTGGAGGGGATGATGGTTCCTGTAACTTGGCGTCAGTA
  GAATATTATAACCCAACAACCGATAAATGGACAGTTGTGTCATCGTGTATGAGCACAGGG
  AGAAGTTATGCAGGGGTCACAGTTATTGATAAACCATTATGA
  
  Clone variation with respect to NM_007246.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007246 unedited
  TTCCCATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGCGCGGCGCCC
  CCTCCGGGCGGATGGAACGCGGCTCGGCGGGCGGGCAGTGCCGGCGTCCGCGGCTGGAAT
  GGTGCTGGCTGTGTTGGTCGGTGCCTGCGTTCTCTGACCCGAGAGGAGCCACAATGGAGA
  CGCCGCCGCTGCCTCCCGCATGCACAAAGCAGGGTCATCAGAAGCCTCTCGATTCAAAAG
  ATGATAATACCGAAAAACACTGCCCAGTGACAGTGAATCCTTGGCATATGAAGAAAGCTT
  TCAAAGTCATGAACGAATTAAGAAGTCAAAATTTGCTGTGCGATGTCACAATTGTGGCAG
  AAGACATGGAAATTTCTGCTCATAGAGTGGTGCTGGCCGCCTGTAGTCCTTATTTTCATG
  CCATGTTTACAGGTGAGATGAGTGAGAGCCGAGCAAAGAGAGTTACAATAAAAGAGGTAG
  ATGGCTGGACCCTGAGGATGCTAATTGATTATGTTTACACTGCACAAATTCACGTTACAG
  AAGAAAATGTACATGTACTTCTCCCACCAGCTGGTCTCTTACAGTTACAGGATGTGAAGA
  AGACTTGTTGNGAATTTTTGGAATCCCAGCTTTACCCTGTCCCCTGCTTAGGAATCCGGG
  CTTTTGCTGATATGCATGCATGTACCGACCTTTTGAACAATGCCACACCTATGCAGAGCA
  ACATTTTGCACATGTTGTCCCTTATGAAAGAATNCTCAATCTTGGCATCGGACAAGTGTG
  CAGCTTAATCTCAAGGGACAAACTTACCTTTCTTTTGAAAAAAAGTTATTGAAGCATAAT
  AGCAGGGTGAACCATGAAAAGATGCGAGGCCAGAGTTATGGCCCGCCTGTAGGACTTGTC
  CGGTACCTTTGCTTCCTCGGCAAACTTATTAAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007246 unedited
  CCCCCCCCCCCCCCCNCCCTTCCCCCCTTTTTTCTTTTTCTGTNCCGNCGGCCGCATTTT
  ACGATCGAGTTTTTTTTTTTTTTTTTTGCAAACAAATAATATACAAACTTTTATTCAAAG
  TTAATTCAAGAAAGACATGTTTTGGTCATTTTTAAAGTGAGATTAATTGAAGATCTCAGA
  AAAACTGTATCTGATCAACACACATGGCTACTCACAGAAAGTTCTCTCTTCTGTTAATAG
  CAGCTAAATTTATACACACAGAAAAAATTCCGAAGACCATGCAAATTCAATTGAATTCCA
  TACATTCATTATATTCATCAAAAACCTGCAGTAATGTTCATGCCAAAGTGTTAATTTAAG
  AAAAAAATTAAAAATACACACCAAAACATGACCAAGATTAAACTAAAGAAAATAATAAAT
  AAGCATAATTTATATTGTATTTTAAAAAGTTTGGCATCACACATATTCAAGTGTGTTACA
  CCAGGTCCATTCCTCAGAAGTGGCATTTAAAGTGTTAAGCATTGTTAAATATCAAAAAAT
  ACAACTCTGTTTTACAATGTAGTACTGGCATAATTCAAAGTACTGTGCCCAATTATAAAT
  AGTATAATCAAGTTTCAAACATCTTTTCAAACATATTTAAAGGAAAGCCTATAGACACAC
  ATTTATATGCACATAATTTATTATATTCATGTAATCAAAGCTATTTTATAAAAGCACACA
  GTGTATCCCTCCCTAGTTTGTATACTTACGTAGACTTTAATATCTGTTTAAAGATTTTCA
  GTTCCTGGTATACAGATTTTTAGAAGAATAAAGATAAAATTAAATTCTTACANGAACCCC
  CATTACTTTATCCTCCTTCACCAGAAAATCTGTATCCATTCAGGGTGAAAGAACTAGCTC
  TTATTGAAAGCAACTGTTGTCTAAAGAATAAAGATTAATTCTTGCAGCCCAGTTTTTTAG
  AAAATTCATC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007246
• ORF Size: 1782 bp
• Insert Size: 3090
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007246.2, NP_009177.2
• RefSeq Size: 3159
• RefSeq ORF: 1782
• Locus ID: 11275
• Domains: BTB, Kelch
• Gene Summary: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation (By similarity). Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1.