SPFH2 (ERLIN2) (NM_007175) Human Untagged Clone

CAT#: SC115663

ERLIN2 (untagged)-Human ER lipid raft associated 2 (ERLIN2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ERLIN2
• Synonyms: C8orf2; Erlin-2; NET32; SPFH2; SPG18
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115663 sequence for NM_007175 edited (data generated by NextGen Sequencing)
  ATGGCTCAGTTGGGAGCAGTTGTGGCTGTGGCTTCCAGTTTCTTTTGTGCATCTCTCTTC
  TCAGCTGTGCACAAGATAGAAGAGGGACATATTGGGGTATATTACAGAGGCGGTGCCCTG
  CTGACTTCGACCAGCGGCCCTGGTTTCCATCTCATGCTCCCTTTCATCACATCATATAAG
  TCTGTGCAGACCACACTCCAGACAGATGAGGTGAAGAATGTACCTTGTGGGACTAGTGGT
  GGTGTGATGATCTACTTTGACAGAATTGAAGTGGTGAACTTCCTGGTCCCGAACGCAGTG
  TATGATATAGTGAAGAACTATACTGCTGACTATGACAAGGCCCTCATCTTCAACAAGATC
  CACCACGAACTGAACCAGTTCTGCAGTGTGCACACGCTTCAAGAGGTCTACATTGAGCTG
  TTTGATCAGATTGATGAAAATCTCAAACTGGCTTTGCAACAGGACCTGACCTCCATGGCC
  CCTGGGCTGGTCATTCAAGCTGTGCGGGTAACAAAGCCCAACATACCAGAGGCAATCCGC
  AGAAACTACGAGTTGATGGAAAGTGAGAAGACAAAGCTTCTCATTGCCGCCCAGAAACAG
  AAGGTGGTGGAAAAGGAAGCAGAGACAGAGCGGAAGAAGGCGCTCATTGAGGCAGAAAAA
  GTGGCCCAGGTGGCTGAGATCACCTACGGGCAGAAGGTGATGGAGAAGGAGACTGAGAAG
  AAGATTTCAGAAATTGAAGATGCTGCATTTCTGGCCCGGGAGAAGGCAAAGGCAGATGCT
  GAGTGCTACACTGCTATGAAAATAGCCGAAGCCAATAAGCTGAAGCTAACCCCTGAATAT
  CTGCAGCTGATGAAGTACAAGGCCATTGCTTCCAACAGCAAGATTTACTTTGGCAAAGAC
  ATTCCTAACATGTTCATGGACTCTGCGGGCAGTGTGAGCAAGCAGTTTGAGGGGCTAGCT
  GACAAGCTAAGCTTTGGCTTAGAAGATGAACCCTTGGAGACGGCCACTAAGGAGAATTGA
  
  Clone variation with respect to NM_007175.6
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007175 unedited
  TACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGAATAGGCAGAGGAGCGCCTGCA
  GGGACAGCCTGGATAAAGGCTCACTGATGGCTCAGTTGGGAGCAGTTGTGGCTGTGGCTT
  CCAGTTTCTTTTGTGCATCTCTCTTCTCAGCTGTGCACAAGATAGAAGAGGGACATATTG
  GGGTATATTACAGAGGCGGTGCCCTGCTGACTTCGACCAGCGGCCCTGGTTTCCATCTCA
  TGCTCCCTTTCATCACATCATATAAGTCTGTGCAGACCACACTCCAGACAGATGAGGTGA
  AGAATGTACCTTGTGGGACTAGTGGTGGTGTGATGATCTACTTTGACAGAATTGAAGTGG
  TGAACTTCCTGGTCCCGAACGCAGTGTATGATATAGTGAAGAACTATACTGCTGACTATG
  ACAAGGCCCTCATCTTCAACAAGATCCACCACGAACTGAACCAGTTCTGCAGTGTGCACA
  CGCTTCAAGAGGTCTACATTGAGCTGTTTGATCAGATTGATGAAAATCTCAAACTGGCTT
  TGCAACAGGACCTGACCTCCATGGCCCCTGNGCTGGTCATTCAAGCTGTGCGGGTAACAA
  AGCCCAACATACCAGAGGCAATCCGCAGAAACTACGAGTTGATGGAAAGTGAGAAGACAA
  AGCTTCTCATTGCCCGCCAGAAACAGAAGGTGGTGGGAAAGGAAGCAGAGACAGAGCGGA
  AGAAGGCGCTCATTGANGCAGAAAAAGTGCCCCAGTGGCTGAAATCACCTACNGGCANAA
  AGTGATGGAGAAAGAGACTGANAANAANATTTCANNAATTGAAGATGCTGCATTTNCTGG
  CCCGGGAGAAGGCAAGGCAGATGCTGAGTGCTACACTGCTATGAAATAGCCCGAGCCATA
  ACTGAAGCTAACCCTTGATTCTGCACTGATGAGTCCAAGGCCTTTGCTTCACGGCAGATT
  ACTTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007175 unedited
  GCCTTTAGCTTGNACCGCGGCCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACA
  CTTCTGCAAAGTTTAATGAAGTGAGAAAACATTCAACCACGGCGATTTTTCCTTGGAAAA
  CCCTACAAAAACTGAATTTTATAACCAGTTACTTACTTCGCAAGATGTTCCATTTATAAA
  TAGTAGCCATTACTTCACTGTCTACAAAATTGCAGGCTGTCACATTTTACATGTCCCACA
  ATTCAAATGTTTTAAGATTAGATTTTCTAGTAACAGCCAAAATAAAACCAAAGTCTACAC
  ACACAGGTTAGTTGTCCTATGCAAATAAACCAGTCGATTCTCATGATTTCGCTACTCCGA
  CCGATCACAGACCCCCCTCGCTCTGCACACTAATGGGTAGGACACCCCATTTCCTTGCTC
  AAAGAGCGACACGCTCCCCCCTCGGCGCGCGCTACTCCCACCACGACTCGACCTTCACTG
  CCGCCCCCCTGCCGCCCTGGGCACCGTCCTTCCATGCCCCCCATCCCCCGCATCCGCTTC
  CCCGCCCATCACCTCACCTCCATCGCTTTTCTTCTAAACCAACTTGTCCCTCCATTCTGT
  TTCCCTCCCCCGTCCCGCGCTCACCTGGCCCGCTCCCCTGCATTCCTATTGTTCCTCTAT
  CCCCACTTCCCCTTCATGGATCTTTCCACTCACCTCCTTTACCATCGTCCGCCCCCTATC
  CGCCCATCGTCCTTCCCCCCTCTTCACCTATTCCCTTTCTACCGCCCAACGGGACTGTCC
  CCATACCAATTCTTCCCTTCCCATTGCCTTCCTTCCGCCTTCTCCCCCTACCTTTCGCTG
  TACCGACAACATCTCCGTTCCCTTCGCACCGTCATTCCTCCTTCACTTGTTTCCGCCCCT
  CTCTCTNNAATGTCCACACCCGCCTATATTGCTCCTTCCTCCTTATCCCCCCACACCCAC
  ACTTCTCCTACTCCGTACACCCACATCCCTTCTCCGATTCCTTAGCGACATCCCACCCTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007175
• ORF Size: 1020 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007175.5, NP_009106.1
• RefSeq Size: 4767
• RefSeq ORF: 1020
• Locus ID: 11160
• Domains: Band_7
• Gene Summary: This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.