WIF1 (NM_007191) Human Untagged Clone

CAT#: SC115674

WIF1 (untagged)-Human WNT inhibitory factor 1 (WIF1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: WIF1
• Synonyms: WIF-1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115674 sequence for NM_007191 edited (data generated by NextGen Sequencing)
  ATGGCCCGGAGGAGCGCCTTCCCTGCCGCCGCGCTCTGGCTCTGGAGCATCCTCCTGTGC
  CTGCTGGCACTGCGGGCGGAGGCCGGGCCGCCGCAGGAGGAGAGCCTGTACCTATGGATC
  GATGCTCACCAGGCAAGAGTACTCATAGGATTTGAAGAAGATATCCTGATTGTTTCAGAG
  GGGAAAATGGCACCTTTTACACATGATTTCAGAAAAGCACAACAGAGAATGCCAGCTATT
  CCTGTCAATATCCATTCCATGAATTTTACCTGGCAAGCTGCAGGGCAGGCAGAATACTTC
  TATGAATTCCTGTCCTTGCGCTCCCTGGATAAAGGCATCATGGCAGATCCAACCGTCAAT
  GTCCCTCTGCTGGGAACAGTGCCTCACAAGGCATCAGTTGTTCAAGTTGGTTTCCCATGT
  CTTGGAAAACAGGATGGGGTGGCAGCATTTGAAGTGGATGTGATTGTTATGAATTCTGAA
  GGCAACACCATTCTCCAAACACCTCAAAATGCTATCTTCTTTAAAACATGTCAACAAGCT
  GAGTGCCCAGGCGGGTGCCGAAATGGAGGCTTTTGTAATGAAAGACGCATCTGCGAGTGT
  CCTGATGGGTTCCACGGACCTCACTGTGAGAAAGCCCTTTGTACCCCACGATGTATGAAT
  GGTGGACTTTGTGTGACTCCTGGTTTCTGCATCTGCCCACCTGGATTCTATGGAGTGAAC
  TGTGACAAAGCAAACTGCTCAACCACCTGCTTTAATGGAGGGACCTGTTTCTACCCTGGA
  AAATGTATTTGCCCTCCAGGACTAGAGGGAGAGCAGTGTGAAATCAGCAAATGCCCACAA
  CCCTGTCGAAATGGAGGTAAATGCATTGGTAAAAGCAAATGTAAGTGTTCCAAAGGTTAC
  CAGGGAGACCTCTGTTCAAAGCCTGTCTGCGAGCCTGGCTGTGGTGCACATGGAACCTGC
  CATGAACCCAACAAATGCCAATGTCAAGAAGGTTGGCATGGAAGACACTGCAATAAAAGG
  TACGAAGCCAGCCTCATACATGCCCTGAGGCCAGCAGGCGCCCAGCTCAGGCAGCACACG
  CCTTCACTTAAAAAGGCCGAGGAGCGGCGGGATCCACCTGAATCCAATTACATCTGGTGA
  
  Clone variation with respect to NM_007191.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007191 unedited
  AAGTTTAGGATTTTGTATACGACTTACTATAGGGNNCGGCCGCGCAATTCGGCACGAGGG
  CGGCACGAGGAGTTTTCCCGGCAGCGAGGAGGTCCTGAGCAGCATGGCCCGGAGGAGCGC
  CTTCCCTGCCGCCGCGCTCTGGCTCTGGAGCATCCTCCTGTGCCTGCTGGCACTGCGGGC
  GGAGGCCGGGCCGCCGCAGGAGGAGAGCCTGTACCTATGGATCGATGCTCACCAGGCAAG
  AGTACTCATAGGATTTGAAGAAGATATCCTGATTGTTTCAGAGGGGAAAATGGCACCTTT
  TACACATGATTTCAGAAAAGCACAACAGAGAATGCCAGCTATTCCTGTCAATATCCATTC
  CATGAATTTTACCTGGCAAGCTGCAGGGCAGGCAGAATACTTCTATGAATTCCTGTCCTT
  GCGCTCCCTGGATAAAGGCATCATGGCAGATCCAACCGTCAATGTCCCTCTGCTGGGAAC
  AGTGCCTCACAAGGCATCAGTTGTTCAAGTTGGTTTCCCATGTCTTGGAAAACAGGATGG
  GGTGGCAGCATTTGAAGTGGATGTGATTGTTATGAATTCTGAAGGCAACACCATTCTCCA
  AACACCTCANAATGCTATCTTCTTTAAAACATGTCAACAAGCTGAGTGCCCAGGCGGGTG
  CCGAAATGGAGGCTTTTGTAATGAAAGACGCATCTGCGAGTGTCCTGATGGGTTCCACGG
  ACCTCACTGTGAGAAAGCCCTTTGTACCCCACGATGTATGAATGGTGGACTTTGTGTGAC
  TCCTGGTTTCTGCATCTGCCCACCTGGATTCTATGGAGTGAACTGTGACANAGCANACTG
  CTCAACCACCTGCTTTAATGGAGGNACCTGTTTCTACCCTGGNAAATGTANNTTGCCTCC
  CAGACTAGAGGGAGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007191 unedited
  ACCGCGGCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTAATACTGAATCTCTGGA
  ATAATGGTAAGGTCAAAATATATTGTATTGAGAGTTTAAAAATTAAGAGCAATTTTTAAA
  AATGTAACAAACATCTAAATATCTGACAATAAAATCTGAAATGCTGTAACTTCAACATTA
  ACTGCACCATCCAAATTCTTGTGACTTACGCATTTTTGCCCAATTTAACCTTTCTGATGT
  TCCCCTGCCCCCAGACACCATAAATGCATTGTAATTTTGAAAATATCTGCCAACTACACA
  CTGAAAATTTTAACCTGATCAATTGACATAATATAAAATCTGTCCCAAAGCACTGAAACA
  AGAAAATCTATACCATCATGCTACAGACGTACTTAGAAAACTTAAAAGGAAGAGTAAATA
  TCAGCTCAGTGATTTATAATGAAGCTAATAAAATTCAGGCCAGTATTCTTAAGTGTAATG
  AACATTATTTGAACATTCAACACATGAAAGGTTAACAAAGGCTATGAACTTGGTGTAACT
  TAAAACGTTTCAGATGTCGGAGTTCACCAGATGTAATTGGATTCAGGTGGATCCCGCCGC
  TCCTCGGCCTTTTTAAGTGAAGGCGTGTGCTGCCTGAGCTGGGCGCCTGCTGGCCTCAGG
  GCATGTATGACGCTGGCTCCGTACTTTTTATTGCAGTGTCTTCCATGCCAACCTTCTTGA
  CATTGCATTTGTTGGGTTATGGCAAGTTCCATGTGCACCACGCCAGCCTTGCAAACAGCT
  TTGAACAAAGTCTCCCTGTAACCTTTGGACATTAAATTGCTTTTACCATGCATTTACCTC
  CTTTCAACAGGTTGTGGGCATTTGCTGAATTAACCTGTTCTTCCTTTAGCCCGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007191
• ORF Size: 1140 bp
• Insert Size: 1830
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_007191.2, NP_009122.1
• RefSeq Size: 2020
• RefSeq ORF: 1140
• Locus ID: 11197
• Domains: WIF, EGF, EGF
• Protein Families: Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
• Protein Pathways: Wnt signaling pathway
• Gene Summary: The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers. [provided by RefSeq, Jun 2010]