CALM1 (NM_006888) Human Untagged Clone

CAT#: SC115829

CALM1 (untagged)-Human calmodulin 1 (phosphorylase kinase, delta) (CALM1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CALM1
• Synonyms: CALML2; caM; CAM2; CAM3; CAMB; CAMC; CAMI; CAMIII; CPVT4; DD132; LQT14; PHKD
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115829 sequence for NM_006888 edited (data generated by NextGen Sequencing)
  ATGGCTGATCAGCTGACCGAAGAACAGATTGCTGAATTCAAGGAAGCCTTCTCCCTATTT
  GATAAAGATGGCGATGGCACCATCACAACAAAGGAACTTGGAACTGTCATGAGGTCACTG
  GGTCAGAACCCAACAGAAGCTGAATTGCAGGATATGATCAATGAAGTGGATGCTGATGGT
  AATGGCACCATTGACTTCCCCGAATTTTTGACTATGATGGCTAGAAAAATGAAAGATACA
  GATAGTGAAGAAGAAATCCGTGAGGCATTCCGAGTCTTTGACAAGGATGGCAATGGTTAT
  ATCAGTGCAGCAGAACTACGTCACGTCATGACAAACTTAGGAGAAAAACTAACAGATGAA
  GAAGTAGATGAAATGATCAGAGAAGCAGATATTGATGGAGACGGACAAGTCAACTATGAA
  GAATTCGTACAGATGATGACTGCAAAATGA
  
  Clone variation with respect to NM_006888.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006888 unedited
  TGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGTGGACGCCGTGCCGTTACT
  CGTAGTCAGGCGGCGGCGCAGGCGGCGGCGGCGGCATAGCGCACAGCGCGCCTTAGCAGC
  AGCAGCAGCAGCAGCAGCATCGGAGGTACCCCCGCCGTCGCAGCCCCCGCGCTGGTGCAG
  CCACCCTCGCTCCCTCTGCTCTTCCTCCCTTCGCTCGCACCATGGCTGATCAGCTGACCG
  AAGAACAGATTGCTGAATTCAAGGAAGCCTTCTCCCTATTTGATAAAGATGGCGATGGCA
  CCATCACAACAAAGGAACTTGGAACTGTCATGAGGTCACTGGGTCAGAACCCAACAGAAG
  CTGAATTGCAGGATATGATCAATGAAGTGGATGCTGATGGTAATGGCACCATTGACTTCC
  CCGAATTTTTGACTATGATGGCTAGAAAAATGAAAGATACAGATAGTGAAGAAGAAATCC
  GTGAGGCATTCCGAGTCTTTGACAAGGATGGCAATGGTTATATCAGTGCAGCAGAACTAC
  GTCACGTCATGACAAACTTAGGAGAAAAACTAACAGATGAAGAAGTAGATGAAATGATCA
  GAGAAGCAGATATTGATGGAGACGGACAAGTCAACTATGAAGAATTCGTACAGATGATGA
  CTGCAAAATGAAGACCTACTTTCAACTCCTTTTTTCCCCCCTCTAGAAGAATCAAATTGA
  ATCTTTTACTTTACCTCTTGCAAAAAAAGAAAAAGAANAAGTTCATTTATTCATTCTGTT
  TCTATATAGCAAACTGATGTCAAAGTACCTTCTGTCCACAACACAAATCTGCAGNATGGG
  TGGGNGGGCCCTGTCCCTAAGATCAGCTCACATCAGTTTACATATAATACTGGGACTACC
  TTATGAAAAGGATC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006888 unedited
  GCTATGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAGTTAATG
  GTCTTTTTATTGGAAAAAAAAAAAAAAAGACTAGCATTTACAACTTGGAATGGACGTAAA
  CTGTAATTTCTTTGAACAGCAATGTTGATGGTTGTGCTGAAGTCCACAGCCACAGCCTAC
  TCTGCCGGCTCCAAGTCATGGTTCAAAAGGTTTTAAAAACAGAGAGTCCAAAGATGCTCC
  CTTGGTAAATGTTTCTTATTAAAAATTTGTGTGAACAGTGACAGCCTGACACCTGTTTCA
  CTCTAGAACAATGCAGACAACGCTAAACCAACATACACGGGCATGCCACCAGGGTGTGTC
  ATCGTCACCATGGGTCGGAGCACACGAAGTACAAGAGGACCATCCTACCAGTGGGGCCAC
  GTCTCAACGGTTTATCCTTCACCCATTTTTCTGCACGTCATCCTGAGGTAAACCAATTTT
  AAATGTGTTTGTTTTCAGTAAACCAGCTATGACAATTTATACTAAACAAATTGAACTAGA
  ACCCATTTGAATAGGTTTTGAATTTGTTTTTTCATTTTTCATTTTTAATACAAAGGCCTG
  ACTGTGCTCAATCGTCAAGCTGCATGCATGAAAAACTGGCCAGCCCAAACAGTGTATTAA
  TCATTAGCAAATGGAACTTTAAGGAGTCCTTATCATTAAGGTAGTACAAGTATTTATATT
  GTAAAACTGATGTGTAGCTTGATCTTTANGGGACAGGACCACCAACCAATACATGCAGAT
  TTTGTGTGTGTGGACAGAAGGTACTTTTGACATTCAGNTNTGCTTATAGAAACAGATGAT
  AAATGACTTTTTTCTTTTTCTTTTTTGCAGAGGTAGTAAAGATCATTTGATTCTCTAAGC
  GGAAAAGAGTGAAAGAGTCTATTTGCAGCATATCTGACAATCTCTANTGACTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006888
• Insert Size: 1500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006888.2, NP_008819.1
• RefSeq Size: 3718 bp
• RefSeq ORF: 450 bp
• Locus ID: 801
• Cytogenetics: 14q32.11
• Domains: EFh
• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway, Glioma, GnRH signaling pathway, Insulin signaling pathway, Long-term potentiation, Melanogenesis, Neurotrophin signaling pathway, Olfactory transduction, Oocyte meiosis, Phosphatidylinositol signaling system, Vascular smooth muscle contraction
• Gene Summary: 'This gene encodes one of three calmodulin proteins which are members of the EF-hand calcium-binding protein family. Calcium-induced activation of calmodulin regulates and modulates the function of cardiac ion channels. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.A missense mutation in the CALM1 gene has been associated with ventricular tachycardia.[provided by RefSeq, May 2020]'