MRG15 (MORF4L1) (NM_006791) Human Untagged Clone

CAT#: SC115850

MORF4L1 (untagged)-Human mortality factor 4 like 1 (MORF4L1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MORF4L1
• Synonyms: Eaf3; FWP006; HsT17725; MEAF3; MORFRG15; MRG15; S863-6
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115850 sequence for NM_006791 edited (data generated by NextGen Sequencing)
  ATGGCGCCGAAGCAGGACCCGAAGCCTAAATTCCAGGAGGGTGAGCGAGTGCTGTGCTTT
  CATGGGCCTCTTCTTTATGAAGCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACAAGTG
  AAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTTCCGGAGAGC
  AGAGTACTCAAATACGTGGACACCAATTTGCAGAAACAGCGAGAACTTCAAAAAGCCAAT
  CAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTGGT
  CTGCAACAGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAAT
  GGAGATGGTGGCAGTACCAGTGAGACCCCTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTA
  GATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGATT
  CCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAG
  CTCTTTTATCTTCCTGCCAAGAAGAATGTGGATTCCATTCTTGAGGATTATGCAAATTAC
  AAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAGGG
  ATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCA
  CAGTATGCTGAAATTCTTGCAGATCATCCCGATGCACCCATGTCCCAGGTGTATGGAGCG
  CCACATCTCCTGAGATTATTTGTACGAATTGGAGCAATGTTGGCTTATACACCTCTGGAT
  GAGAAGAGCCTTGCTTTATTACTCAATTATCTTCACGATTTCCTAAAGTACCTGGCAAAG
  AATTCTGCAACTTTGTTCAGTGCCAGCGATTATGAAGTGGCTCCTCCTGAGTACCATCGG
  AAAGCTGTGTGA
  
  Clone variation with respect to NM_006791.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006791 unedited
  TACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGATGTAGAGCTGGCAGTGCC
  TGACGGCGCGTCTGACGCGGAGTTGGGTGGGGTAGAGAGTAGGGGGCGGTAGTCGGGGGT
  GGTGGGAGAAGGAGGAGGCGGCGAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGC
  CTAAATTCCAGGAGGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAAGCAA
  AGTGTGTAAAGGTTGCCATAAAGGACAAACAAGTGAAATACTTCATACATTACAGTGGTT
  GGAATAAAAATTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCA
  ATTTGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGA
  TGAGAGGGGCTGCCCCAGGAAAGAAGACATCTGGTCTGCAACAGAAAAATGTTGAAGTGA
  AAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTACCAGTGAGA
  CCCCTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAA
  CATTCATGAACAGAGTTGAAGTTAAAGTAAAGATTCCTGAAGAGCTAAAACCGTGGCTTG
  TTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGCAAGAAGAT
  GTGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATATA
  ANGAGTATGCGGNTAAATGAAAGTTGTGCAGGNATAAAAGAATACTTCACGTATGGTGGG
  TACCCAGCTACTCTATAAATTGGAGACCACATATGCTGAAATCTTGCAGATATCCCGATG
  CACCATGTNCCCAGTGTATGGAGCGCACATTNCTGAGATNATTGTACAAATGNAGCATGT
  GCTTAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006791 unedited
  NNNNNTTTTTTATTTGNANGCGGCCGCAATCTANATCGAGTTTTTTTTTTTTTTTTTTCT
  TTGAAATTTAAAGAAAAAATTATTGAAGATCTGAAAAACATTCCTAAAAAATTGACTTTT
  CCAGAAAACTAGCTACACAATGCATTGCGTCTATCATGTTAAAACGTGCATTAGACACAA
  ATACAAAAACCATGAAACAAGCCACCATTCTTCAACAATTTGAGCCAAGATAAAATGCCT
  AAGTAACAACATGGATGACTTGCAAAGGATGGGCTCTTTACTTTAAGCACCTTANAAAAA
  AACAAAAGCACAAATGGGATGAGTGGTGNNTCAGTATATACACTGAANTNGAACCTTTGG
  CACTAGGAATCAGAGCATTTTGTCATATAGCATTAACATGTATTATAAAAGTGCGTANTG
  GTCAAGGATTANAACCACCAGCATTCAAAAGCAGCTTTGTCAACTAGGCAATAAAACACT
  CTACAGCATATTCCTTCTGTTGGCCATCATTGAAAACACTGGGCAGCATTTTTGGATTGG
  AAAAAAAAAAGGAAGAAAGGAAAAAGGGGCCTTTACCCCCTTTTATTTTTTCTTTGTTAA
  ATTCCAACGGAAACCAAACTCCATTGGTATACCCTAACCTTTTAAAAGCACTTGTTTGTC
  CCAGAAATTGGCTAAAACCAAAAGGGGGTTCCGGGGAATCCAACCTAGGGGAGGGAAAGG
  CCTTTTACAACGTTTTCCCAGGGGTCCCAGGGGGGCCCCTTTTTAATTCCTGGGCCTGGA
  AAAAGTTGGAAAATTTTTGCCCGGTCCTTTGGGAAATCGGAAAAAATTTGGGTATAAAAC
  GGGGGTTTTTCTATCACAAGGGGGTAAACCAAATTTGTCCCATTTTCACAAAAAATTGGA
  GAAAAGGGGGGCCCCAACCCGGGGAAAAGGGGGCCCGGGATAAATCCCAAAAATTCACCT
  CCGGGGTTTTAAAATTTAAAAACGGGGGCCCCCCATCCGGAGGAATTTTTTCCGCCGCCA
  CTAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006791
• ORF Size: 972 bp
• Insert Size: 1790
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006791.2, NP_006782.1
• RefSeq Size: 1852
• RefSeq ORF: 972
• Locus ID: 10933
• Domains: CHROMO
• Protein Families: Transcription Factors
• Gene Summary: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes isoform 1.