Peroxiredoxin 3 (PRDX3) (NM_006793) Human Untagged Clone

CAT#: SC115851

PRDX3 (untagged)-Human peroxiredoxin 3 (PRDX3), nuclear gene encoding mitochondrial protein, transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRDX3
• Synonyms: AOP-1; AOP1; HBC189; MER5; PRO1748; prx-III; SP-22
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_006793, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCTGCTGTAGGACGGTTGCTCCGAGCGTCGGTTGCCCGACATGTGAGTGCCATTCCTTGGGGCA
  TTTCTGCCACTGCAGCCCTCAGGCCTGCTGCATGTGGAAGAACGAGCTTGACAAATTTATTGTGTTCTGG
  TTCCAGTCAAGCAAAATTATTCAGCACCAGTTCCTCATGCCATGCACCTGCTGTCACCCAGCATGCACCC
  TATTTTAAGGGTACAGCCGTTGTCAATGGAGAGTTCAAAGACCTAAGCCTTGATGACTTTAAGGGGAAAT
  ATTTGGTGCTTTTCTTCTATCCTTTGGATTTCACCTTTGTGTGTCCTACAGAAATTGTTGCTTTTAGTGA
  CAAAGCTAACGAATTTCACGACGTGAACTGTGAAGTTGTCGCAGTCTCAGTGGATTCCCACTTTAGCCAT
  CTTGCCTGGATAAATACACCAAGAAAGAATGGTGGTTTGGGCCACATGAACATCGCACTCTTGTCAGACT
  TAACTAAGCAGATTTCCCGAGACTACGGTGTGCTGTTAGAAGGTTCTGGTCTTGCACTAAGAGGTCTCTT
  CATAATTGACCCCAATGGAGTCATCAAGCATTTGAGCGTCAACGATCTCCCAGTGGGCCGAAGCGTGGAA
  GAAACCCTCCGCTTGGTGAAGGCGTTCCAGTATGTAGAAACACATGGAGAAGTCTGCCCAGCGAACTGGA
  CACCGGATTCTCCTACGATCAAGCCAAGTCCAGCTGCTTCCAAAGAGTACTTTCAGAAGGTAAATCAGTA
  G
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006793 unedited
  ACCCGATTTGTAATCCGACTTTTATATAGGGCGGCAGCGCAATTCGCACGAGGGCGCCCG
  AGTGCACTGAAGATGGCGGCTGCTGTAGGACGGTTGCTCCGAGCGTCGGTTGCCCGACAT
  GTGAGTGCCATTCCTTGGGGCATTTCTGCCACTGCAGCCCTCAGGCCTGCTGCATGTGGA
  AGAACGAGCTTGACAAATTTATTGTGTTCTGGTTTTCTTCAAGCAAAATTATTCAGCACC
  AGTTCCTCATGCCATGCACCTGCTGTCACCCAGCATGCACCCTATTTTAAGGGTACAGCC
  GTTGTCAATGGAGAGTTCAAAGACCTAAGCCTTGATGACTTTAAGGGGAAATATTTGGTG
  CTTTTCTTCTATCCTTTGGATTTCACCTTTGTGTGTCCTACAGAAATTGTTGCTTTTAGT
  GACAAAGCTAACGAATTTCACGATGTGAACTGTGAAGTTGTCGCAGTCTCAGTGGATTCC
  CACTTTAGCCATCTTGCCTGGATAAATACACCAAGAAAGAATGGTGGTTTGGGCCACATG
  AACATCGCACTCTTGTCAGACTTAACTAAGCAGATTTCCCGAGACTACGGTGTGCTGTTA
  GAAGGTTCTGGTCTTGCACTAAGAGGTCTCTTCATAATTGACCCCAATGGAGTCATCAAG
  CATTTGAGCGTCAACGATCTCCCAGTGGGCCGAAGCGTGGAAGAAACCCTCCGCTTGGTG
  AAAGCGTTCCAGTATGTAGAAACACATGGAGAAGTCTGCCCAGCGAACTGGACACCCGNA
  TTCTCCTACGATCAAGCCAAGTTCAGCTGCTTCCAAGAGTACTTTCAGAAAGGTAATCAG
  TAGATCACCATGTGTATCTGCACCTTCTTCACTGAGAGAAGAACCACAGTGAAACCCTGC
  TTTATCATTTTCAGATGGTAATTGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006793 unedited
  GTAATTCTTGNCCGCGGCCGCATTCTANATCGAGTTTTTTTTTTTTTTTTTTGTTAAAAT
  GCAAATGTTTTAAAATATGTTTATTTTGTATGTTTTACAATGAATACTTCAGCAAAGAAA
  ATAATTATAATTTCAAAATGCAATCCCTGGATTTGATAAATATCCTTTATAATCGATTAC
  ACTAATCAATATCTAGAAATATACATAGACAAAGTTAGCTAATGAATAAAATAAGTAAAA
  TGACTACATAAACTCAATTTCAGGGATGAGGGATCATGCATGATCAATTAAGTCACTCTG
  CCACTTTTTAAAATAATACGATTCACATTTGCTTCAATCACATAAACATTCATTGCAGGA
  GTTACACGGCTAATCATGGAAAATTATGATCTTTGTTAGCTTAAAAGAAAATTCAGTTTA
  ATACAAAGACATTCAAGATGAAAATTTCAGGACCGTTGATCAGAAGCTTTCAATGTGTGT
  TGCTCTACTTTATTATAGGCAAGATTCAAGTAAGGCTAAGAAAGAAGAGTGTTTCCATTG
  AGACATGATCTAAGAATAGCCTTCTATAGAGGCAAATTATGTTCTGTAGAAACTAGCTAG
  CCAGCCACCAAGATGTTACCAATAAAGGATTCCTTGTACTAGCAACTAACCATGTTTAAA
  AGGTCTTAGCCAGAATTACAAAAACAAAACATTTAGAGTAATACTTATGAATACAAGCAT
  AATTGGTTCCTTGCCTTCTACAAATACCATCTTNGAAATGATAAAAGCAGGTTTCAACTG
  TGGGTCTTCTCTCAGTTGAGAGGTGCAGATCACATGGGTGATCTACTGATTTACCTCCTG
  AATACTCTTTGAAACAGCTGGACTTGCCTGTATCGTAGAGAATCCGTGTCAGTTGCTGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006793
• ORF Size: 771 bp
• Insert Size: 1710
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_006793.2, NP_006784.1
• RefSeq Size: 1591
• RefSeq ORF: 771
• Locus ID: 10935
• Domains: AhpC-TSA
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).